Compile Data Set for Download or QSAR
maximum 50k data
Found 165 of ic50 for UniProtKB: P00469
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50226275(CHEMBL267104)
Affinity DataIC50:  0nMAssay Description:Compound was evaluated for inhibitory effect on the thymidylate synthase (TS) of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(2-[(4-{[(2,4-diaminopteridin-6-yl)methyl](methyl)a...)
Affinity DataIC50:  2.64nMAssay Description:Compound was evaluated for inhibitory effect on the thymidylate synthase (TS) of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50226277(CHEMBL273509)
Affinity DataIC50:  2.78nMAssay Description:Compound was evaluated for inhibitory effect on the thymidylate synthase (TS) of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50226276(CHEMBL11139)
Affinity DataIC50:  3.86nMAssay Description:Compound was evaluated for inhibitory effect on the thymidylate synthase (TS) of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18771((2S)-2-[(4-{[(2-amino-4-oxo-1,4-dihydroquinazolin-...)
Affinity DataIC50:  9nMAssay Description:Inhibition of Lactobacillus casei thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50028408((R)-2-{4-[(2-Amino-4-oxo-1,4-dihydro-quinazolin-6-...)
Affinity DataIC50:  9nMpH: 7.4Assay Description:Inhibition of Lactobacillus casei thymidylate synthetase at 37 degree C pH 7.4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against thymidylate synthase derived from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022235(4-(4-{4-[4-(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022231(4-{4-[4-(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylm...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022234(4-[4-(4-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmeth...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022233(4-(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)
Affinity DataIC50:  20nMAssay Description:Inhibitory concentration of compound to inhibit Thymidylate synthase (TS) in L1210 cells at conc. of 200 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50029547(2-[4-(2-Amino-6-methyl-4-oxo-4,4a,7,7a-tetrahydro-...)
Affinity DataIC50:  21nMAssay Description:Inhibitory activity against thymidylate Synthase from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)
Affinity DataIC50:  21nMAssay Description:Inhibition of thymidyllate synthase in Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)
Affinity DataIC50:  21nMAssay Description:Evaluated for the inhibition of thymidylate synthase in L. caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022232(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)-et...)
Affinity DataIC50:  21nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50008294(2-(4-(((2-amino-4-oxo-1,4-dihydroquinazolin-6-yl)m...)
Affinity DataIC50:  36nMAssay Description:Inhibitory activity against thymidylate Synthase from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50017876(2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylme...)
Affinity DataIC50:  60nMAssay Description:Inhibitory concentration of compound to inhibit Thymidylate synthase (TS) in L1210 cells at conc. of 200 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50012244(2-{4-[(2-Methyl-4-oxo-3,4-dihydro-quinazolin-6-ylm...)
Affinity DataIC50:  100nMAssay Description:Inhibition of thymidyllate synthase in Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50011243(2-{4-[(4-Hydroxy-quinazolin-6-ylmethyl)-prop-2-yny...)
Affinity DataIC50:  160nMAssay Description:Inhibitory concentration of compound to inhibit Thymidylate synthase (TS) in L1210 cells at conc. of 200 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50017875(2-{4-[Ethyl-(4-oxo-3,4-dihydro-quinazolin-6-ylmeth...)
Affinity DataIC50:  520nMAssay Description:Inhibitory concentration of compound to inhibit Thymidylate synthase (TS) in L1210 cells at conc. of 200 microMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016789(CHEMBL3273846)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of MTX-resistant Lactobacillus casei thymidylate synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50006906(2-{4-[(2-Amino-4-hydroxy-quinazolin-6-ylmethyl)-am...)
Affinity DataIC50:  2.44E+3nMAssay Description:Inhibitory concentration of compound to inhibit Thymidylate synthase (TS) in L1210 cells at conc. of 200 uMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022738(2-{4-[2-(2,4-Diamino-5-methyl-pyrido[2,3-d]pyrimid...)
Affinity DataIC50:  2.90E+3nMAssay Description:Evaluated for inhibition of thymidylate synthase (TS) from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50161779((S)-2-(5-Dimethylamino-naphthalene-1-sulfonylamino...)
Affinity DataIC50:  3.40E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme assay were performed spectrophotometrically by following the absorbance at 340nm using a hewlett Packard 8453 UV spectrophotometer equippe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50161779((S)-2-(5-Dimethylamino-naphthalene-1-sulfonylamino...)
Affinity DataIC50:  3.40E+3nMAssay Description:Affinity assay of specificities of thymidylate synthase (TS)inhibitorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50023906(2-{4-[(2-Amino-4-oxo-1,4-dihydro-pteridin-6-ylmeth...)
Affinity DataIC50:  3.90E+3nMAssay Description:Ability to inhibit thymidylate synthase derived from Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50008291(2-{4-[(2-Amino-4-oxo-1,4-dihydro-pteridin-6-ylmeth...)
Affinity DataIC50:  3.90E+3nMAssay Description:The compound was tested for its inhibitory activity (IC50) against thymidylate synthase(TS) derived from L. caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016790(CHEMBL3273847)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of MTX-resistant Lactobacillus casei thymidylate synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022236((S)-2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-...)
Affinity DataIC50:  4.40E+3nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM40770(2-naphthylsulfonyl)
Affinity DataIC50:  4.70E+3nMAssay Description:Affinity assay of specificities of thymidylate synthase (TS)inhibitorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM36702(Dansyltyrosine deriviative 20B)
Affinity DataIC50:  4.70E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme assay were performed spectrophotometrically by following the absorbance at 340nm using a hewlett Packard 8453 UV spectrophotometer equippe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016791(CHEMBL3273855)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of MTX-resistant Lactobacillus casei thymidylate synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM36710(Dansyltyrosine deriviative 29B)
Affinity DataIC50:  7.00E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme assay were performed spectrophotometrically by following the absorbance at 340nm using a hewlett Packard 8453 UV spectrophotometer equippe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50000058(CHEMBL3230503)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Lactobacillus casei thymidylate synthetase using dUMP as substrate preincubated for 20 mins followed by substrate additionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016796(CHEMBL3273852)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of MTX-resistant Lactobacillus casei thymidylate synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM36687(Dansyltyrosine deriviative 4B)
Affinity DataIC50:  8.80E+3nMpH: 7.4 T: 2°CAssay Description:The enzyme assay were performed spectrophotometrically by following the absorbance at 340nm using a hewlett Packard 8453 UV spectrophotometer equippe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM36709(Dansyltyrosine deriviative 28B)
Affinity DataIC50:  1.00E+4nMpH: 7.4 T: 2°CAssay Description:The enzyme assay were performed spectrophotometrically by following the absorbance at 340nm using a hewlett Packard 8453 UV spectrophotometer equippe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM36705(Dansyltyrosine deriviative 24B)
Affinity DataIC50:  1.00E+4nMpH: 7.4 T: 2°CAssay Description:The enzyme assay were performed spectrophotometrically by following the absorbance at 340nm using a hewlett Packard 8453 UV spectrophotometer equippe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM36701(Dansyl derivative, 3L | Dansyltyrosine deriviative...)
Affinity DataIC50:  1.00E+4nMpH: 7.4 T: 2°CAssay Description:The enzyme assay were performed spectrophotometrically by following the absorbance at 340nm using a hewlett Packard 8453 UV spectrophotometer equippe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM36711(Dansyltyrosine deriviative 30B)
Affinity DataIC50:  1.10E+4nMpH: 7.4 T: 2°CAssay Description:The enzyme assay were performed spectrophotometrically by following the absorbance at 340nm using a hewlett Packard 8453 UV spectrophotometer equippe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022237((S)-2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016797(CHEMBL3273853)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of MTX-resistant Lactobacillus casei thymidylate synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50161778((S)-3-[4-(5-Dimethylamino-naphthalene-1-sulfonylox...)
Affinity DataIC50:  1.35E+4nMpH: 7.4 T: 2°CAssay Description:The enzyme assay were performed spectrophotometrically by following the absorbance at 340nm using a hewlett Packard 8453 UV spectrophotometer equippe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50022388(2-{4-[(2-Amino-4-hydroxy-pyrido[3,2-d]pyrimidin-6-...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibitory activity against thymidylate synthase of Lactobacillus caseiMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016798(CHEMBL3273854)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of MTX-resistant Lactobacillus casei thymidylate synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM36688(Dansyltyrosine deriviative 5B)
Affinity DataIC50:  1.67E+4nMpH: 7.4 T: 2°CAssay Description:The enzyme assay were performed spectrophotometrically by following the absorbance at 340nm using a hewlett Packard 8453 UV spectrophotometer equippe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016800(CHEMBL3273851)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of MTX-resistant Lactobacillus casei thymidylate synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM36699(Dansyl derivative, 8L | Dansyltyrosine deriviative...)
Affinity DataIC50:  1.90E+4nMpH: 7.4 T: 2°CAssay Description:The enzyme assay were performed spectrophotometrically by following the absorbance at 340nm using a hewlett Packard 8453 UV spectrophotometer equippe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50016801(CHEMBL3273849)
Affinity DataIC50:  1.90E+4nMAssay Description:Inhibition of MTX-resistant Lactobacillus casei thymidylate synthetaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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