TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 1.20nMAssay Description:Inhibition of thymidin synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibitory activity against thymidylate synthase of Streptococcus faeciumMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 5.5nMAssay Description:Inhibitory activity against thymidylate synthase of Streptococcus faeciumMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 6.30nMAssay Description:Inhibitory activity against thymidylate synthase of Streptococcus faeciumMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 8.90nMAssay Description:Inhibition of thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of Thymidylate synthase (unknown origin)More data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against thymidylate synthase of Streptococcus faeciumMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibitory activity against thymidylate synthase of Streptococcus faeciumMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of pure human thymidyllate synthase from extract of Manca human lymphoma cellsMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Compound was evaluated for the inhibition at a given concentration against Lactobacillus casei Thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of human TS using dUMP and methylene-THF as substrate by kaleidagraph analysisMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of human TS using dUMP and methylene-THF as substrate by kaleidagraph analysisMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of human TS assessed as oxidation of tetrahydrofolate to dihydrofolate after 2 to 12 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition of human TS assessed as oxidation of tetrahydrofolate to dihydrofolate after 2 to 12 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Compound was evaluated for the inhibition at a given concentration against Lactobacillus casei TSMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Compound was evaluated for the inhibition at a given concentration against recombinant human TSMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibitory activity against thymidylate Synthase from human recombinant sourcesMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 36nMAssay Description:Inhibition of thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Ability to inhibit thymidylate synthase derived from human leukemia K562 cellsMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 40nMpH: 7.4 T: 2°CAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 40nMAssay Description:Inhibition of thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Compound was evaluated for the inhibition at a given concentration against recombinant human Thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibitory activity against thymidylate Synthase from human recombinant sourcesMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 42nMAssay Description:Inhibition of human TS assessed as oxidation of tetrahydrofolate to dihydrofolate after 2 to 12 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 45nMAssay Description:Inhibition of thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 46nMpH: 7.4 T: 2°CAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 51nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 54nMpH: 7.4 T: 2°CAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 54nMpH: 7.4 T: 2°CAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 54nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 54nMpH: 7.4 T: 2°CAssay Description:TS was assayed spectrophotometrically in the reaction buffer solution containing (6R, 6S)-5, 10-CH2H4folate. The reaction was initiated by the additi...More data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibitory concentration against isolated Lactobacillus casei Thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Compound was evaluated as inhibitor of Lactobacillus casei thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 55nMAssay Description:Inhibitory concentration against Lactobacillus casei Thymidylate synthase (TS).More data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of thymidylate synthaseMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of GAR formyltransferase in Lactobacillus caseiMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of various kinase enzyme.More data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 60nMAssay Description:Inhibition of pure human thymidyllate synthase from extract of Manca human lymphoma cellsMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 64nMAssay Description:Inhibition of human TS assessed as oxidation of tetrahydrofolate to dihydrofolate after 2 to 12 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:In vitro inhibition of human thymidylate synthase (TS)More data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of human TS assessed as oxidation of tetrahydrofolate to dihydrofolate after 2 to 12 mins by spectrophotometryMore data for this Ligand-Target Pair
TargetThymidylate synthase(Homo sapiens (Human))
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Institute of Theoretical Studies gGmbH
Curated by ChEMBL
Affinity DataIC50: 68nMAssay Description:Inhibition of thymidylate synthaseMore data for this Ligand-Target Pair