Compile Data Set for Download or QSAR
maximum 50k data
Found 37 of kd for UniProtKB: P10827
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataKd:  1.20nMAssay Description:Thyroid hormone competitive binding assay using TNT T7 quick-coupled transcription translation system from promega.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50115668(3,5-dimethyl-4-(4'-hydroxy-3'-isopropylbenzyl)phen...)
Affinity DataKd:  2.5nMAssay Description:Binding affinity to human TRalpha1More data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataKd:  0.0580nMAssay Description:Thyroid hormone competitive binding assay using TNT T7 quick-coupled transcription translation system from promega.More data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataKd:  0.0580nMAssay Description:Human thyroid hormone receptor alpha and beta (hTR alpha1) and (hTR beta1) were produced using TNT coupled reticulocyte lysate system from Promega.More data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50115668(3,5-dimethyl-4-(4'-hydroxy-3'-isopropylbenzyl)phen...)
Affinity DataKd:  0.440nMAssay Description:Human thyroid hormone receptor alpha and beta (hTR alpha1) and (hTR beta1) were produced using TNT coupled reticulocyte lysate system from Promega.More data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50130595(2-Amino-3-[4-(4-hydroxy-3-isopropyl-phenoxy)-3,5-d...)
Affinity DataKd:  9.70nMAssay Description:Human thyroid hormone receptor alpha and beta (hTR alpha1) and (hTR beta1) were produced using TNT coupled reticulocyte lysate system from Promega.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50105667(CHEMBL98135 | {4-[4-Hydroxy-1-(4-hydroxy-3-isoprop...)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity of the compound towards thyroid hormone receptor (hTR alpha 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50105668(CHEMBL264527 | {4-[11-(Butyl-methyl-carbamoyl)-1-(...)
Affinity DataKd:  240nMAssay Description:Binding affinity of the compound towards thyroid hormone receptor (hTR alpha 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataKd:  0.170nMAssay Description:Binding affinity of the compound towards thyroid hormone receptor (hTR alpha 1)More data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50105670(CHEMBL318132 | {4-[11-(Butyl-methyl-carbamoyl)-1-(...)
Affinity DataKd:  112nMAssay Description:Binding affinity of the compound towards thyroid hormone receptor (hTR alpha 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50105671(CHEMBL97187 | {4-[(2,4-Dimethoxy-phenyl)-(4-hydrox...)
Affinity DataKd:  1.40E+3nMAssay Description:Binding affinity of the compound towards thyroid hormone receptor (hTR alpha 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50105669(CHEMBL97613 | {4-[1-(4-Hydroxy-3-isopropyl-phenyl)...)
Affinity DataKd:  430nMAssay Description:Binding affinity of the compound towards thyroid hormone receptor (hTR alpha 1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM18884(2-(4-{[4-hydroxy-3-(4-nitrophenyl)-5-(propan-2-yl)...)
Affinity DataKd:  200nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50115666(CHEMBL109430 | {4-[4-Hydroxy-3-isopropyl-5-(4-pent...)
Affinity DataKd:  5.20nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50115667(CHEMBL111953 | [4-(4-Hydroxy-3-isopropyl-5-phenyle...)
Affinity DataKd:  490nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataKd:  0.100nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50115668(3,5-dimethyl-4-(4'-hydroxy-3'-isopropylbenzyl)phen...)
Affinity DataKd:  1.80nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50115669(CHEMBL110158 | {4-[3-(4-Amino-phenylethynyl)-4-hyd...)
Affinity DataKd:  330nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM18885(2-[4-({4-hydroxy-3-[2-(4-nitrophenyl)ethynyl]-5-(p...)
Affinity DataKd:  93nMAssay Description:Binding affinity against human Thyroid hormone receptor alpha1 (hTRalpha1) using radiolabeled T3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataKd:  0.0600nMAssay Description:Binding affinity of compound was determined against Thyroid hormone receptor alpha1More data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50115668(3,5-dimethyl-4-(4'-hydroxy-3'-isopropylbenzyl)phen...)
Affinity DataKd:  0.660nMAssay Description:Binding affinity of compound was determined against Thyroid hormone receptor alpha1More data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50130595(2-Amino-3-[4-(4-hydroxy-3-isopropyl-phenoxy)-3,5-d...)
Affinity DataKd:  8.5nMAssay Description:Binding affinity of compound was determined against Thyroid hormone receptor alpha1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50130594(3-[4-(4-Hydroxy-3-isopropyl-benzyl)-3,5-dimethyl-p...)
Affinity DataKd:  0.690nMAssay Description:Binding affinity of compound was determined against Thyroid hormone receptor alpha1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50130596(CHEMBL419016 | [4-(4-Hydroxy-3-isopropyl-phenoxy)-...)
Affinity DataKd:  2.40nMAssay Description:Binding affinity of compound was determined against Thyroid hormone receptor alpha1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50130597(2-Amino-3-[4-(4-hydroxy-3-isopropyl-benzyl)-3,5-di...)
Affinity DataKd:  2.02nMAssay Description:Binding affinity of compound was determined against Thyroid hormone receptor alpha1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM18860((2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-di...)
Affinity DataKd:  0.0580nMAssay Description:Displacement of [125I]T3 from human TRalpha receptorMore data for this Ligand-Target Pair
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50375342(CHEMBL258886)
Affinity DataKd:  43nMAssay Description:Displacement of [125I]T3 from human TRalpha receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50375343(CHEMBL259096)
Affinity DataKd:  24nMAssay Description:Displacement of [125I]T3 from human TRalpha receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50375344(CHEMBL407819)
Affinity DataKd:  1.70E+3nMAssay Description:Displacement of [125I]T3 from human TRalpha receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50375345(CHEMBL264153)
Affinity DataKd:  15nMAssay Description:Displacement of [125I]T3 from human TRalpha receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50375346(CHEMBL264152)
Affinity DataKd:  42nMAssay Description:Displacement of [125I]T3 from human TRalpha receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50375347(CHEMBL264410)
Affinity DataKd:  82nMAssay Description:Displacement of [125I]T3 from human TRalpha receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM36487(CHEMBL263630 | CO23)
Affinity DataKd:  1.20nMAssay Description:Displacement of [125I]T3 from human TRalpha receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50375350(CHEMBL263631)
Affinity DataKd:  17nMAssay Description:Displacement of [125I]T3 from human TRalpha receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50375349(CHEMBL260482)
Affinity DataKd:  25nMAssay Description:Displacement of [125I]T3 from human TRalpha receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM18884(2-(4-{[4-hydroxy-3-(4-nitrophenyl)-5-(propan-2-yl)...)
Affinity DataKd:  200nMAssay Description:Antagonist activity at human TRalpha1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM36488(CO22)
Affinity DataKd:  286nMAssay Description:Thyroid hormone competitive binding assay using TNT T7 quick-coupled transcription translation system from promega.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed