Compile Data Set for Download or QSAR
maximum 50k data
Found 301 of ic50 for UniProtKB: P08648
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461540(CHEMBL4226033)
Affinity DataIC50:  0.0500nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461545(CHEMBL4226876)
Affinity DataIC50:  0.190nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50495950(Danoprevir | R-05190591 | R05190591 | RO-5190591 |...)
Affinity DataIC50:  0.200nMAssay Description:Inhibitory activity against HIV-1 Mutant Reverse transcriptase K103NMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461549(CHEMBL4225009)
Affinity DataIC50:  0.210nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461552(CHEMBL4228791)
Affinity DataIC50:  0.220nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461537(CHEMBL4228440)
Affinity DataIC50:  0.240nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461556(CHEMBL4225149)
Affinity DataIC50:  0.270nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461547(CHEMBL4225051)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1 [T112H](Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279568((3S)-3-[3-bromo-5-(trifluoromethyl)phenyl]-3-[[2-[...)
Affinity DataIC50:  0.300nMAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 2 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461555(CHEMBL4225768)
Affinity DataIC50:  0.340nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461554(CHEMBL4225514)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461539(CHEMBL4229110)
Affinity DataIC50:  0.440nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461551(CHEMBL4229052)
Affinity DataIC50:  0.460nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1 [T112H](Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279570((3S)-3-[3-bromo-5-methyl-phenyl)-3-(2-(3-hydroxy-5...)
Affinity DataIC50:  0.5nMAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 2 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-1 [T112H](Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279562((3S)-3-[3-chloro-5-(difluoromethyl)phenyl)-3-(2-(3...)
Affinity DataIC50:  0.5nMAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 2 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-1 [T112H](Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279573((3S)-3-(3,5-dibromophenyl)-3-[[2-[[5-[(5-hydroxy-1...)
Affinity DataIC50:  0.600nMAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 2 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-1 [T112H](Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279572((3S)-3-[3-bromo-5-fluoro-phenyl)-3-(2-(3-hydroxy-5...)
Affinity DataIC50:  0.600nMAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 2 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-1 [T112H](Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279567((3S)-3-(3-bromo-5-chloro-phenyl)-3-[[2-[[5-[(5-hyd...)
Affinity DataIC50:  0.600nMAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 2 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-1 [T112H](Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279565((3S)-3-[3-bromo-5-chloro-phenyl)-3-(2-(3-hydroxy-5...)
Affinity DataIC50:  0.600nMAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 2 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-1 [T112H](Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279566((3S)-3-[3-chloro-5-(trifluoromethyl)phenyl]3-[[2-[...)
Affinity DataIC50:  0.700nMAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 2 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461542(CHEMBL4224705)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1 [T112H](Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279563((3S)-3-[3-bromo-5-(difluoromethyl)phenyl)-3-(2-(3-...)
Affinity DataIC50:  0.700nMAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 2 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-1 [T112H](Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279564((3S)-3-[3-chloro-5-(trifluoromethyl)phenyl)-3-(2-(...)
Affinity DataIC50:  0.800nMAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 2 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-1 [T112H](Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279561((3S)-3-(3-bromo-5-(trifluoromethyl)phenyl)-3-(2-(3...)
Affinity DataIC50:  0.800nMAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 2 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461541(CHEMBL4225301)
Affinity DataIC50:  0.820nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461564(CHEMBL4228533)
Affinity DataIC50:  0.900nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50287594(Asunaprevir | BMS 650032 | BMS-650032)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50287622(CHEMBL4160876)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant full length HCV genotype 1a NS3/4A protease (1027 to 1711 residues) expressed in Escherichia coli strain BL21 (DE3) using R...More data for this Ligand-Target Pair
TargetIntegrin alpha-5/beta-1 [T112H](Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279560((3S)-3-(3,5-dibromophenyl)-3-(2-(3-hydroxy-5-((5-h...)
Affinity DataIC50:  1nMAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 2 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-1 [T112H](Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279569((3S)-3-[3,5-bis(trifluoromethyl)phenyl)-3-(2-(3-hy...)
Affinity DataIC50:  1nMAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 2 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-1 [T112H](Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279574((3S)-3-[3,5-dichloro-phenyl)-3-(2-(3-hydroxy-5-((5...)
Affinity DataIC50:  1nMAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 2 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50287594(Asunaprevir | BMS 650032 | BMS-650032)
Affinity DataIC50:  1nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
TargetIntegrin alpha-5/beta-1 [T112H](Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279575((3S)-3-[3-chloro-5-(trifluoromethoxy)phenyl)-3-(2-...)
Affinity DataIC50:  1nMAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 2 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIntegrin alpha-5/beta-1 [T112H](Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279576((3S)-3-(3-bromo-5-(trifluoromethoxy)phenyl)-3-(2-(...)
Affinity DataIC50:  1nMAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 2 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461562(CHEMBL4227396)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461565(CHEMBL4228402)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetIntegrin alpha-5/beta-1 [T112H](Homo sapiens (Human))
Saint Louis University

US Patent
LigandPNGBDBM279571((3S)-3-[3-chloro-5-methyl-phenyl)-3-(2-(3-hydroxy-...)
Affinity DataIC50:  2nMAssay Description:Purified human fibronectin (R&D Systems, 1918-FN) diluted to 2 μg/mL in TBS+ buffer (25 mM Tris pH 7.4, 137 mM NaCl, 2.7 mM KCl, 1 mM CaCl2, 1 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50485492(Grazoprevir | Grazoprevir monohydrate | MK-5172 | ...)
Affinity DataIC50:  2nMAssay Description:Inhibition of Epidermal growth factor receptor autophosphorylation in A431 human epidermoid carcinoma cellsMore data for this Ligand-Target Pair
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50110122((S)-4-((S)-2-Acetylamino-3-carboxy-propionylamino)...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50122900((5R,8S,11S,14S,17S,20S)-20-acetamido-14-benzhydryl...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461553(CHEMBL4228282)
Affinity DataIC50:  2nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461550(CHEMBL2403888)
Affinity DataIC50:  2nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461543(CHEMBL4229158)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461538(CHEMBL4227401)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461535(CHEMBL4226548)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461546(CHEMBL4225716)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50537589(CHEMBL4287268)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against HIV-1 Y188L reverse transcriptase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461558(CHEMBL4227183)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 2b NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50461536(CHEMBL4225561)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of N-terminal poly-His tagged recombinant HCV genotype 1a NS3/4A protease expressed in Escherichia coli BL21(DE3) pLysS using HCV-FRET pep...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGenome polyprotein/Non-structural protein 4A(Hepatitis C virus)
Bristol-Myers Squibb Research And Development

Curated by ChEMBL
LigandPNGBDBM50122902(4-(2-Acetylamino-3-carboxy-propionylamino)-4-(1-{1...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity against Hepatitis C NS3/NS4A proteaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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