Compile Data Set for Download or QSAR
(2D       Computed 3D by Vconf -m prep )

Data curated solely by BindingDB

Found 10 hits of affinity data for UniProtKB/TrEMBL: O70370

Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	pH	Temp °C
Cathepsin S Mus musculus (mouse)	2-cyano-pyrropyrimidine, 2 (7-(2-cyclohexylethyl)-6-[4-(4-acetylpiperazin-1-yl...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI PC cid PC sid	PubMed	n/a	n/a	10.0	n/a	n/a	7	22
Novartis					J Med Chem. 51: 5502-5 (2008)
Cathepsin S Mus musculus (mouse)	phenyl-containing analogue, 14 ((2S)-N-(cyanomethyl)-3-cyclohexyl-2-(phenylformami...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	n/a	n/a	13.0	n/a	40.0	6.5	22
Merck Frosst Centre for Therapeutic Research					J Med Chem. 48: 7535-43 (2005)
Cathepsin S Mus musculus (mouse)	2-cyano-pyrropyrimidine, 7a (7-(2-cyclohexylethyl)-6-[4-(4-acetylpiperazin-1-yl...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	14.0	n/a	n/a	7	22
Novartis					J Med Chem. 51: 5502-5 (2008)
Cathepsin S Mus musculus (mouse)	2-cyano-pyrropyrimidine, 7g (7-[2-(4,4-difluorocyclohexyl)ethyl]-6-[4-(4-acetyl...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	20.0	n/a	n/a	7	22
Novartis					J Med Chem. 51: 5502-5 (2008)
Cathepsin S Mus musculus (mouse)	aryl-morpholino-containing analogue, 13 (N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-(morpho...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	n/a	n/a	4500.0	n/a	8500.0	6.5	22
Merck Frosst Centre for Therapeutic Research					J Med Chem. 48: 7535-43 (2005)
Cathepsin S Mus musculus (mouse)	CRA-013783/L-006235 (N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-[2-(4-m...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS PC cid PC sid	PubMed	n/a	n/a	5400.0	n/a	318.0	6.5	22
Merck Frosst Centre for Therapeutic Research					J Med Chem. 48: 7535-43 (2005)
Cathepsin S Mus musculus (mouse)	Balicatib (N-[1-(cyanomethylcarbamoyl)cyclohexyl]-4-(4-propyl...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS PC cid PC sid	PubMed	n/a	n/a	6350.0	n/a	480.0	6.5	22
Merck Frosst Centre for Therapeutic Research					J Med Chem. 48: 7535-43 (2005)
Cathepsin S Mus musculus (mouse)	aryl-morpholino-containing analogue, 12 (N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-[2-(mor...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	n/a	n/a	8500.0	n/a	6700.0	6.5	22
Merck Frosst Centre for Therapeutic Research					J Med Chem. 48: 7535-43 (2005)
Cathepsin S Mus musculus (mouse)	piperazine-containing compound, 2 (4-[2-(4-methylpiperazin-1-yl)-1,3-thiazol-4-yl]-N-...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	n/a	n/a	33000.0	n/a	>10000.0	6.5	22
Merck Frosst Centre for Therapeutic Research					J Med Chem. 48: 7535-43 (2005)
Cathepsin S Mus musculus (mouse)	piperazine-containing compound, 11 ((2R)-N-(cyanomethyl)-4-methyl-2-{3-[4-(piperazin-1...)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS PC cid PC sid	PubMed	n/a	n/a	34100.0	n/a	740.0	6.5	22
Merck Frosst Centre for Therapeutic Research					J Med Chem. 48: 7535-43 (2005)

• Reorder this table by ec50
• Reorder this table by ic50
• Reorder this table by kd
• Reorder this table by pH
• Reorder this table by T
• Change energy unit to:  kcal/mole