TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.0540nMAssay Description:Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.0740nMAssay Description:Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.0870nMAssay Description:Inhibition of [125I]-Cholecystokinin-8 binding to Cholecystokinin type B receptor of guinea pig cerebral cortical membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.0870nMAssay Description:Compound was evaluated for the inhibition of 124 I-CCK-8 binding at Cholecystokinin type B receptor on guinea pig cerebral cortical membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.0933nMAssay Description:Displacement of [125I]-CCK-8 from human CCK2R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Binding activity against Cholecystokinin type B receptor from guinea pig cortex using [125]BH CCK-8s as radioligand.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Binding activity towards cholecystokinin-A (CCK-A) receptor in guinea pig pancreasMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Displacement of [125I]-BH CCK-8S from Cholecystokinin type B receptor in guinea pig cortexMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Inhibition of ligand binding to Cholecystokinin type B receptor from guinea pig cortical membrane.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.100nMAssay Description:Binding activity towards cholecystokinin-B (CCK-B) receptor in guinea pig cortexMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.110nMAssay Description:Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.120nMAssay Description:Displacement of [125I]CCK-8s from human recombinant CCK-B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.120nMAssay Description:Displacement of [125I]CCK-8s from human recombinant CCK2 receptor expressed in CHO cells measured after 60 mins by scintillation counting methodMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.132nMAssay Description:Displacement of [125I]-CCK-8 from human CCK2R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.132nMAssay Description:Displacement of [125I]-CCK-8 from human CCK2R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.138nMAssay Description:In vitro displacement of [125I]BH-CCK-8 from cDNA of human Cholecystokinin type B receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.142nMAssay Description:The compound was tested for binding activity against Cholecystokinin type B receptor from rat pancreatic tissue using [125]BH CCK-8 as radioligandMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.151nMAssay Description:Displacement of [125I]-CCK-8 from human CCK2R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.158nMAssay Description:Displacement of [125I]-CCK-8 from human CCK2R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.166nMAssay Description:Displacement of [125I]-CCK-8 from human CCK2R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125I]-BH-CCK- binding to cholecystokinin type B receptor from jurkat TcellsMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.200nMAssay Description:Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.209nMAssay Description:Displacement of [125I]-CCK-8 from human CCK2R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.220nMAssay Description:Binding activity towards cholecystokinin-B (CCK-B) receptor in guinea pig cortexMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.220nMAssay Description:Inhibition of binding of [125I]-CCK-8 to the cholecystokinin type B receptorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.229nMAssay Description:Binding affinity against human Cholecystokinin type B receptor by displacement of [125I]CCK-8More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.240nMAssay Description:Evaluated in vitro for its binding affinity towards cholecystokinin type B receptor of guinea pig cortexMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.240nMAssay Description:Inhibition of binding of [125I]-CCK-8 to the cholecystokinin type B receptorMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.240nMAssay Description:Binding affinity towards Cholecystokinin type B receptor was measured by displacement of [125I]-CCK from guinea pig cortical membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.260nMAssay Description:Binding activity towards cholecystokinin-B (CCK-B) receptor in guinea pig cortexMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.266nMAssay Description:The compound was tested for binding activity against Cholecystokinin type B receptor from rat pancreatic tissue using [125]BH CCK-8 as radioligandMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.270nMAssay Description:Binding affinity towards Cholecystokinin type B receptor was measured by displacement of [125I]-CCK from guinea pig cortical membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:In vitro test for inhibition of [125I]-CCK binding to Cholecystokinin type B receptor from guinea pig cortical membranes was determinedMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Displacement of [125 I] CCK-8 from Cholecystokinin type B receptor of guinea pig cerebral cortexMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Ability to inhibit the binding of [125I]-gastrin to gastric glands in guinea pig.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Binding activity against Cholecystokinin type B receptor from guinea pig cortex using [125]BH CCK-8s as radioligand.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Binding affinity towards Cholecystokinin type B receptor was measured by displacement of [125I]-CCK from guinea pig cortical membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.280nMAssay Description:Inhibition of ligand binding to Cholecystokinin type B receptor from guinea pig cortical membrane.More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.288nMAssay Description:Displacement of [125I]-CCK-8 from human CCK2R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.288nMAssay Description:Displacement of [125I]-CCK-8 from human CCK2R expressed in human 1321N1 cell membranes after 2 hrs by SPA assayMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.290nMAssay Description:In vitro binding affinity against Cholecystokinin type B receptor in guinea pig brain membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.290nMAssay Description:Inhibition of [125I]-BH-CCK- binding to cholecystokinin type B receptor from guinea pig brain membranesMore data for this Ligand-Target Pair
TargetCholecystokinin receptor type A/Gastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Centre De Pharmacologie-Endocrinologie (Montpellier, France)
Curated by ChEMBL
Centre De Pharmacologie-Endocrinologie (Montpellier, France)
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Ability of compound to Inhibit the binding of [125I]BH-CCK-8 to Cholecystokinin receptor in isolated guinea pig brain membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Inhibition of [125 I]BH CCK-8S binding to Cholecystokinin type B receptor in guinea pig cortical membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Evaluated in vitro for its binding affinity towards cholecystokinin type B receptor of guinea pig cortexMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.300nMAssay Description:Binding affinity towards Cholecystokinin type B receptor was measured by displacement of [125I]-CCK from guinea pig cortical membranesMore data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.316nMAssay Description:Displacement of CCK-8 from human Cholecystokinin type B receptor expressing CHO cell membranes More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.316nMAssay Description:Tested for 50% displacement of [125I]CCK-8 from membrane preparation isolated from CHO-K1 cells stably transfected with the cDNA of human Cholecystok...More data for this Ligand-Target Pair
TargetGastrin/cholecystokinin type B receptor(Homo sapiens (Human))
Neuroscience Research Centre
Curated by ChEMBL
Neuroscience Research Centre
Curated by ChEMBL
Affinity DataIC50: 0.320nMAssay Description:In vitro displacement of [125I]BH-CCK-8 from cDNA of human Cholecystokinin type B receptor expressed in CHO-K1 cellsMore data for this Ligand-Target Pair