Compile Data Set for Download or QSAR
maximum 50k data
Found 430 of ec50 for UniProtKB: P29274
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50451378(CHEMBL39106)
Affinity DataEC50:  0nMAssay Description:AE maximal score at Adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50451381(CHEMBL38779)
Affinity DataEC50:  0nMAssay Description:AE maximal score at Adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50451379(CHEMBL43299)
Affinity DataEC50:  0.00100nMAssay Description:AE maximal score at Adenosine A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50368543(CHEMBL605668)
Affinity DataEC50:  0.191nMAssay Description:Concentration required for coronary arteries vasodilation at the Adenosine A2 receptor in langendorff guinea pig heart preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50230152(Binodenoson | Corvue | MRE0470 | WRC-0470)
Affinity DataEC50:  0.257nMAssay Description:In vitro effect on coronary vasodilation in guinea pig heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50421975(CHEMBL611607)
Affinity DataEC50:  0.324nMAssay Description:In vitro effect on coronary vasodilation in guinea pig heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50421890(CHEMBL2311197)
Affinity DataEC50:  0.389nMAssay Description:Concentration required for coronary arteries vasodilation at the Adenosine A2 receptor in langendorff guinea pig heart preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50421980(CHEMBL2113592)
Affinity DataEC50:  0.468nMAssay Description:In vitro effect on coronary vasodilation in guinea pig heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50406504(CHEMBL605878)
Affinity DataEC50:  0.501nMAssay Description:Concentration required for coronary arteries vasodilation at the Adenosine A2 receptor in langendorff guinea pig heart preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50513547(CHEMBL4471366)
Affinity DataEC50:  0.640nMAssay Description:Agonist activity at human adenosine receptor A2A expressed in HEK293 cells assessed as cAMP accumulation incubated for 30 mins by Eu-cAMP tracer-base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50421982(CHEMBL608663)
Affinity DataEC50:  0.692nMAssay Description:In vitro effect on coronary vasodilation in guinea pig heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50385948(CHEMBL2042304)
Affinity DataEC50:  0.850nMAssay Description:Agonist activity at human adenosine A2A receptor expressed in CHO cells assessed as increase in intracellular cAMP level after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50406519(CHEMBL606080)
Affinity DataEC50:  0.871nMAssay Description:Concentration required for coronary arteries vasodilation at the A2 adenosine receptor in langendorff guinea pig heart preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50595579(CHEMBL5203469)
Affinity DataEC50:  0.900nMAssay Description:Antagonist activity at wild type human A2AAR expressed in CHO cells assessed as inhibition of CGS21680-induced cAMP accumulation preincubated for 20 ...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50421985(CHEMBL611916)
Affinity DataEC50:  1nMAssay Description:In vitro effect on coronary vasodilation in guinea pig heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50150766((2R,3R,4S,5R)-2-(6-amino-2-((S)-1-hydroxy-3-phenyl...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at human recombinant adenosine A2A receptor expressed in CHO cells assessed as induction of cyclic AMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50513551(CHEMBL4447310)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human adenosine receptor A2A expressed in HEK293 cells assessed as cAMP accumulation incubated for 30 mins by Eu-cAMP tracer-base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50600755(CHEMBL5171148)
Affinity DataEC50:  1.20nMAssay Description:Antagonist activity at A2AAR in human T -cells assessed as increase in IL-2 production preincubated for 1 hr followed by CD3/CD28 monoclonal antibody...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50600757(CHEMBL5208415)
Affinity DataEC50:  1.40nMAssay Description:Antagonist activity at A2AAR in human T -cells assessed as increase in IL-2 production preincubated for 1 hr followed by CD3/CD28 monoclonal antibody...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM35804((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Affinity DataEC50:  1.40nMAssay Description:Partial agonist activity at human A2A receptor expressed in HEK293 cell membranes assessed as intrinsic activity by measuring cell index change withi...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50513554(CHEMBL4438487)
Affinity DataEC50:  1.40nMAssay Description:Agonist activity at human adenosine receptor A2A expressed in HEK293 cells assessed as cAMP accumulation incubated for 30 mins by Eu-cAMP tracer-base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50150762((2R,3R,4S,5R)-2-{6-Amino-2-[(S)-1-hydroxymethyl-2-...)
Affinity DataEC50:  1.40nMAssay Description:Potency against cAMP formation in CHO cells expressing recombinant human A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50406499(CHEMBL605463)
Affinity DataEC50:  1.40nMAssay Description:Concentration required for coronary arteries vasodilation at the A2 adenosine receptor in langendorff guinea pig heart preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50600758(CHEMBL5174275)
Affinity DataEC50:  1.60nMAssay Description:Antagonist activity at A2AAR in human T -cells assessed as increase in IL-2 production preincubated for 1 hr followed by CD3/CD28 monoclonal antibody...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50406511(CHEMBL604836)
Affinity DataEC50:  1.60nMAssay Description:Concentration required for coronary arteries vasodilation at the Adenosine A2 receptor in langendorff guinea pig heart preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50150765((2R,3R,4S,5R)-2-{6-Amino-2-[(S)-2-(4-bromo-phenyl)...)
Affinity DataEC50:  1.60nMAssay Description:Potency against cAMP formation in CHO cells expressing recombinant human A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50600748(CHEMBL5176737)
Affinity DataEC50:  1.80nMAssay Description:Antagonist activity at A2AAR in human T -cells assessed as increase in IL-2 production preincubated for 1 hr followed by CD3/CD28 monoclonal antibody...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50421983(CHEMBL608966)
Affinity DataEC50:  1.80nMAssay Description:In vitro effect on coronary vasodilation in guinea pig heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50406503(CHEMBL606081)
Affinity DataEC50:  1.90nMAssay Description:Concentration required for coronary arteries vasodilation at the A2 adenosine receptor in langendorff guinea pig heart preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50009509((CGS 22,492) 2-[6-Amino-2-(2-cyclohexyl-ethylamino...)
Affinity DataEC50:  1.90nMAssay Description:In vitro effect on coronary vasodilation in guinea pig heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50421972(CHEMBL611921)
Affinity DataEC50:  2nMAssay Description:In vitro effect on coronary vasodilation in guinea pig heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50385955(CHEMBL2042311)
Affinity DataEC50:  2.02nMAssay Description:Agonist activity at human adenosine A2A receptor expressed in CHO cells assessed as increase in intracellular cAMP level after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM35804((CGS21680) 3-(4-{2-[6-Amino-9-(5-ethylcarbamoylmet...)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at human adenosine A2a receptor expressed in CHO cells assessed as stimulation of cAMP formation after 24 hrsMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50009535((CGS 22,989) 2-[6-Amino-2-(2-cyclohex-1-enyl-ethyl...)
Affinity DataEC50:  2.20nMAssay Description:In vitro effect on coronary vasodilation in guinea pig heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50078422(CHEMBL3414936)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at human recombinant adenosine A2A receptor transfected in CHO cells assessed as induction of adenylyl cyclase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataEC50:  2.5nMAssay Description:Irreversible agonist activity at human adenosine A2A receptor expressed in Flp-In-CHO cells assessed as effect on forskolin-induced cAMP accumulation...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50406518(CHEMBL604422)
Affinity DataEC50:  2.60nMAssay Description:Concentration required for coronary arteries vasodilation at the Adenosine A2 receptor in langendorff guinea pig heart preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50406510(CHEMBL605876)
Affinity DataEC50:  2.60nMAssay Description:Concentration required for coronary arteries vasodilation at the A2 adenosine receptor in langendorff guinea pig heart preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50406501(CHEMBL606092)
Affinity DataEC50:  2.80nMAssay Description:Concentration required for coronary arteries vasodilation at the A2 adenosine receptor in langendorff guinea pig heart preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50266652(CHEMBL4078479)
Affinity DataEC50:  2.90nMAssay Description:Agonist activity at recombinant human adenosine A2A receptor expressed in CHO cell membranes assessed as stimulation of adenylyl cyclase activity by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50421979(CHEMBL607585)
Affinity DataEC50:  2.90nMAssay Description:In vitro effect on coronary vasodilation in guinea pig heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50406514(CHEMBL605873)
Affinity DataEC50:  3nMAssay Description:Concentration required for coronary arteries vasodilation at the Adenosine A2 receptor in langendorff guinea pig heart preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50003647(CHEMBL3235280)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human adenosine A2A receptor expressed in HEK293 cells assessed as increase in intracellular cAMP level after 30 mins by EIAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50150764((2R,3R,4S,5R)-2-{6-Amino-2-[(S)-1-hydroxymethyl-2-...)
Affinity DataEC50:  3.10nMAssay Description:Potency against cAMP formation in CHO cells expressing recombinant human A2A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50421986(CHEMBL610443)
Affinity DataEC50:  3.30nMAssay Description:In vitro effect on coronary vasodilation in guinea pig heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at human A2A-AR expressed in FlpIn-CHO cells assessed as inhibition of forskolin-stimulated cAMP accumulation preincubated for 40 mi...More data for this Ligand-Target Pair
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50406521(CHEMBL605461)
Affinity DataEC50:  3.40nMAssay Description:Concentration required for coronary arteries vasodilation at the Adenosine A2 receptor in langendorff guinea pig heart preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50421976(CHEMBL607796)
Affinity DataEC50:  3.5nMAssay Description:In vitro effect on coronary vasodilation in guinea pig heart.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Homo sapiens (Human))
University Of South Florida

Curated by ChEMBL
LigandPNGBDBM50406509(CHEMBL605667)
Affinity DataEC50:  3.70nMAssay Description:Concentration required for coronary arteries vasodilation at the Adenosine A2 receptor in langendorff guinea pig heart preparationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a(Homo sapiens (Human))
University Of Virginia

Curated by ChEMBL
LigandPNGBDBM50078423(CHEMBL3414937)
Affinity DataEC50:  3.80nMAssay Description:Agonist activity at human recombinant adenosine A2A receptor transfected in CHO cells assessed as induction of adenylyl cyclase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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