Compile Data Set for Download or QSAR
maximum 50k data
Found 24 of ec50 for UniProtKB: P05177
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50538668(CHEMBL4634455 | US11518761, Example 159)
Affinity DataEC50:  460nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate measured after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50577263(CHEMBL4850236)
Affinity DataEC50:  1.90E+3nMAssay Description:Induction of CYP1A2 in human hepatocytesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM372346(Method A: (R)-4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13a...)
Affinity DataEC50: >5.00E+3nMAssay Description:Induction of CYP1A2 in human hepatocyteMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50448495(CHEMBL3126836)
Affinity DataEC50: >1.30E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50538670(CHEMBL4642579)
Affinity DataEC50:  2.08E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate measured after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50114572(CHEMBL3608916)
Affinity DataEC50:  2.39E+4nMAssay Description:Inhibition of human CYP1A2 by luminometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50348709(CHEMBL1801062)
Affinity DataEC50:  3.50E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50448494(CHEMBL3126657)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50448496(CHEMBL3126835)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50448497(CHEMBL3126834)
Affinity DataEC50: >4.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes after 30 mins in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50249403(CHEMBL4091821)
Affinity DataEC50: >5.00E+4nMAssay Description:Induction of CYP1A2 in cryopreserved human hepatocytes measured after 48 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50275377(CHEMBL520237 | S-2-(6-(4-(3-(dimethylamino)propoxy...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50538669(CHEMBL4646408)
Affinity DataEC50:  5.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using phenacetin as substrate measured after 10 mins by LC-MS/MS analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50275432(CHEMBL487965 | S-2-(6-(1,4-dihydrobenzo[d][1,2]dio...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50114568(CHEMBL3608913)
Affinity DataEC50:  7.88E+4nMAssay Description:Inhibition of human CYP1A2 by luminometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50348710(CHEMBL1801506)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50348732(CHEMBL1801504)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50246760(CHEMBL4075348)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50114574(CHEMBL3608921)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2 by luminometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50348733(CHEMBL1801060)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50114571(CHEMBL3608915)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2 by luminometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50566257(CHEMBL4785210)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50437753(CHEMBL2409564)
Affinity DataEC50: >1.00E+5nMAssay Description:Induction of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Washington University School Of Medicine

Curated by ChEMBL
LigandPNGBDBM50114573(CHEMBL3608920)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human CYP1A2 by luminometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed