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Found 16 hits affinity hit(s) for enzyme = Prostaglandin D Synthase with UniProtKB: O60760
Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	pH	Temp °C
Prostaglandin D Synthase Homo sapiens (human)	Pyrazolylthiazole, 13 (2-phenyl-5-(1H-pyrazol-3-yl)-1,3-thiazole)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PDB PubChem	PDB PubMed	n/a	n/a	21.0	n/a	n/a	7.2	22
AstraZeneca			CSLS PDB PubChem	PDB PubMed	J Med Chem. 51: 2178-86 (2008)
Prostaglandin D Synthase Homo sapiens (human)	Phenylisothiazole-5-carboxamide, 15 (N-[4-methyl-3-({3-[(4-methylpiperazin-1-yl)methyl]...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PubChem	PubMed	n/a	n/a	75.0	n/a	n/a	7.2	22
AstraZeneca			PubChem	PubMed	J Med Chem. 51: 2178-86 (2008)
Prostaglandin D Synthase Homo sapiens (human)	Thiazolylamino, 12 (4-{[4-(4-fluoro-3-methylphenyl)-1,3-thiazol-2-yl]a...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PDB PubChem	PDB PubMed	n/a	n/a	138.0	n/a	n/a	7.2	22
AstraZeneca			CSLS PDB PubChem	PDB PubMed	J Med Chem. 51: 2178-86 (2008)
Prostaglandin D Synthase Homo sapiens (human)	Pyrazolylisoxazole, 14 (3-phenyl-5-(1H-pyrazol-3-yl)-1,2-oxazole \| 3-pheny...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PDB PubChem	PDB PubMed	n/a	n/a	920.0	n/a	n/a	7.2	22
AstraZeneca			CSLS PDB PubChem	PDB PubMed	J Med Chem. 51: 2178-86 (2008)
Prostaglandin D Synthase Homo sapiens (human)	Thiazole, 4 (4-{[4-(2-methoxyphenyl)-1,3-thiazol-2-yl]amino}ben...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PubChem	PubMed	n/a	n/a	994.0	n/a	n/a	7.2	22
AstraZeneca			PubChem	PubMed	J Med Chem. 51: 2178-86 (2008)
Prostaglandin D Synthase Homo sapiens (human)	Pyridine-3-carboxylate (methyl 6-(3-pyridin-4-yl-1H-1,2,4-triazol-5-yl)pyr...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PubChem	PubMed	n/a	n/a	1500.0	n/a	n/a	7.2	22
AstraZeneca			PubChem	PubMed	J Med Chem. 51: 2178-86 (2008)
Prostaglandin D Synthase Homo sapiens (human)	Indeno[1,2-c]pyridazin-5-one (3-(4-methylphenyl)-5H-indeno[1,2-c]pyridazin-5-one)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	3800.0	n/a	n/a	7.2	22
AstraZeneca			CSLS PubChem	PubMed	J Med Chem. 51: 2178-86 (2008)
Prostaglandin D Synthase Homo sapiens (human)	Indeno[1,2-c]pyridazin-5-one, 6 (3-(4-methoxyphenyl)-5H-indeno[1,2-c]pyridazin-5-on...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	3800.0	n/a	n/a	7.2	22
AstraZeneca			CSLS PubChem	PubMed	J Med Chem. 51: 2178-86 (2008)
Prostaglandin D Synthase Homo sapiens (human)	Tranilast (2-[(2E)-3-(3,4-dimethoxyphenyl)prop-2-enamido]benz...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PDB PubChem	PDB PubMed	n/a	n/a	11600.0	n/a	n/a	7.2	22
AstraZeneca			CSLS PDB PubChem	PDB PubMed	J Med Chem. 51: 2178-86 (2008)
Prostaglandin D Synthase Homo sapiens (human)	Methoxynaphthalen-1-yl, 8 (2-bromo-1-(4-methoxynaphthalen-1-yl)ethan-1-one \| ...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	12400.0	n/a	n/a	7.2	22
AstraZeneca			CSLS PubChem	PubMed	J Med Chem. 51: 2178-86 (2008)
Prostaglandin D Synthase Homo sapiens (human)	Phenol, 11 (2,4-dichloro-6-(1H-pyrazol-5-yl)phenol)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	17400.0	n/a	n/a	7.2	22
AstraZeneca	Phenol, 11 (2,4-dichloro-6-(1H-pyrazol-5-yl)phenol)		CSLS PubChem	PubMed	J Med Chem. 51: 2178-86 (2008)
Prostaglandin D Synthase Homo sapiens (human)	Pyrazole, 9 (3-(3,5-dimethyl-1H-pyrrol-2-yl)-1H-pyrazole)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	26400.0	n/a	n/a	7.2	22
AstraZeneca	Pyrazole, 9 (3-(3,5-dimethyl-1H-pyrrol-2-yl)-1H-pyrazole)		CSLS PubChem	PubMed	J Med Chem. 51: 2178-86 (2008)
Prostaglandin D Synthase Homo sapiens (human)	Pyrazol-5-amine, 5 (4-(3,4-dimethoxyphenyl)-1-phenyl-1H-pyrazol-5-amin...)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	33000.0	n/a	n/a	7.2	22
AstraZeneca			CSLS PubChem	PubMed	J Med Chem. 51: 2178-86 (2008)
Prostaglandin D Synthase Homo sapiens (human)	Pyridine, 10 (2-methyl-5-(1H-pyrazol-5-yl)pyridine)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PubChem	PubMed	n/a	n/a	34700.0	n/a	n/a	7.2	22
AstraZeneca	Pyridine, 10 (2-methyl-5-(1H-pyrazol-5-yl)pyridine)		CSLS PubChem	PubMed	J Med Chem. 51: 2178-86 (2008)
Prostaglandin D Synthase Homo sapiens (human)	Phenylpyridazine-3-carboxylate, 7 (ethyl 5-methoxy-6-phenylpyridazine-3-carboxylate)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PubChem	PubMed	n/a	n/a	45000.0	n/a	n/a	7.2	22
AstraZeneca			PubChem	PubMed	J Med Chem. 51: 2178-86 (2008)
Prostaglandin D Synthase Homo sapiens (human)	Pyrazole, 1 (1-phenyl-1H-pyrazole-4-carboxylic acid)	B.MOAD DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PDB PubChem	PDB PubMed	n/a	n/a	890000.0	n/a	n/a	7.2	22
AstraZeneca	Pyrazole, 1 (1-phenyl-1H-pyrazole-4-carboxylic acid)		CSLS PDB PubChem	PDB PubMed	J Med Chem. 51: 2178-86 (2008)

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