Compile Data Set for Download or QSAR
maximum 50k data
Found 186 of ic50 data for polymerid = 2214,2215,50000932,50006975
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101069(10,10-Bis-trifluoromethyl-9,10-dihydro-anthracene-...)
Affinity DataIC50:  0.190nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101068(4-Chloro-10,10-dioxo-9,10-dihydro-10lambda*6*-thio...)
Affinity DataIC50:  0.270nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101051(4,5-Dichloro-9H-xanthene-9-carboxylic acid [(2R,3R...)
Affinity DataIC50:  0.300nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101058(4-Phenyl-9H-xanthene-9-carboxylic acid [(2R,3R,4S,...)
Affinity DataIC50:  0.660nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101048(4-Chloro-9H-xanthene-9-carboxylic acid [(2R,3R,4S,...)
Affinity DataIC50:  0.850nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101050(10,10-Dioxo-9,10-dihydro-10lambda*6*-thioxanthene-...)
Affinity DataIC50:  0.930nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101071(10,10-Dioxo-9,10-dihydro-10lambda*6*-thioxanthene-...)
Affinity DataIC50:  0.950nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101060(4-Trifluoromethyl-9H-xanthene-9-carboxylic acid [(...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101072(2-(2,6-Dichloro-phenyl)-N-[(2R,3S,5R)-5-(5-ethyl-2...)
Affinity DataIC50:  1nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101062(4-Chloro-9H-thioxanthene-9-carboxylic acid [(2R,3R...)
Affinity DataIC50:  1.5nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101049(10,10-Dimethyl-9,10-dihydro-anthracene-9-carboxyli...)
Affinity DataIC50:  1.5nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101047(4-Methyl-9H-xanthene-9-carboxylic acid [(2R,3R,4S,...)
Affinity DataIC50:  1.60nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101074(4-Methoxy-9H-xanthene-9-carboxylic acid [(2R,3R,4S...)
Affinity DataIC50:  1.70nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101067((S)-2-(2,4-Dichloro-5-methoxy-phenoxy)-N-[(2R,3R,4...)
Affinity DataIC50:  1.80nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101045(9H-Xanthene-9-carboxylic acid [(2R,3R,4S,5R)-5-(5-...)
Affinity DataIC50:  2.10nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101073(4,5-Dimethyl-9H-xanthene-9-carboxylic acid [(2R,3R...)
Affinity DataIC50:  2.20nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101053(9H-Xanthene-9-carboxylic acid [(2R,3S,5R)-5-(5-eth...)
Affinity DataIC50:  2.90nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101044(9,10-Dihydro-anthracene-9-carboxylic acid [(2R,3S,...)
Affinity DataIC50:  7nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101043(9H-Thioxanthene-9-carboxylic acid [(2R,3R,4S,5R)-5...)
Affinity DataIC50:  8.5nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101064(9H-Thioxanthene-9-carboxylic acid [(2R,3S,5R)-5-(5...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 2)
Glsynthesis

LigandPNGBDBM21885(2,9-disubstituted 6-oxopurine, 12i | 9-[4-(decahyd...)
Affinity DataKi:  5nM IC50:  13nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101046(10-Methyl-9,10-dihydro-acridine-9-carboxylic acid ...)
Affinity DataIC50:  23nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101059(9H-Fluorene-9-carboxylic acid [(2R,3S,5R)-5-(5-eth...)
Affinity DataIC50:  28nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101065(2-(2,6-Dimethyl-phenyl)-N-[(2R,3S,5R)-5-(5-ethyl-2...)
Affinity DataIC50:  40nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 2)
Glsynthesis

LigandPNGBDBM21887(2,9-disubstituted 6-oxopurine, 12k | 2-(phenylamin...)
Affinity DataIC50:  47nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 2)
Glsynthesis

LigandPNGBDBM21884(2,9-disubstituted 6-oxopurine, 12h | 9-{4-[2-(2-hy...)
Affinity DataIC50:  65nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 2)
Glsynthesis

LigandPNGBDBM21893(2,9-disubstituted 6-oxopurine, 12q | 2-(phenylamin...)
Affinity DataIC50:  90nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101070(2-(2-Chloro-phenyl)-N-[(2R,3S,5R)-5-(5-ethyl-2,4-d...)
Affinity DataIC50:  100nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50210810(2-(3-Trifluoromethyl-phenylamino)-1,9-dihydro-puri...)
Affinity DataIC50:  100nMAssay Description:Inhibition of TdR phosphorylation using thymidine kinase assay for herpes simplex virus type 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 2)
Glsynthesis

LigandPNGBDBM21888(2,9-disubstituted 6-oxopurine, 12l | 2-(phenylamin...)
Affinity DataIC50:  130nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 2)
Glsynthesis

LigandPNGBDBM21891(2,9-disubstituted 6-oxopurine, 12o | 9-[4-(4-metho...)
Affinity DataIC50:  140nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1)
Glsynthesis

LigandPNGBDBM21885(2,9-disubstituted 6-oxopurine, 12i | 9-[4-(decahyd...)
Affinity DataKi:  30nM ΔG°:  -10.7kcal/mole IC50:  150nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 2)
Glsynthesis

LigandPNGBDBM21892(2,9-disubstituted 6-oxopurine, 12p | 9-[4-(3-metho...)
Affinity DataIC50:  150nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50210810(2-(3-Trifluoromethyl-phenylamino)-1,9-dihydro-puri...)
Affinity DataIC50:  151nMAssay Description:Inhibitory activity against HSV-1 thymidine kinase isolated from HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101061(CHEMBL297987 | N-[(2R,3S,5R)-5-(5-Ethyl-2,4-dioxo-...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 2)
Glsynthesis

LigandPNGBDBM21895(2,9-disubstituted 6-oxopurine, 12s | 9-(4-{4-[4-ch...)
Affinity DataIC50:  200nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101055(CHEMBL44996 | N-[(2R,3S,5R)-5-(5-Ethyl-2,4-dioxo-3...)
Affinity DataIC50:  200nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 2)
Glsynthesis

LigandPNGBDBM21882(2,9-disubstituted 6-oxopurine, 12f | 2-(phenylamin...)
Affinity DataIC50:  220nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 2)
Glsynthesis

LigandPNGBDBM21894(1-{4-[6-oxo-2-(phenylamino)-6,9-dihydro-3H-purin-9...)
Affinity DataIC50:  220nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 2)
Glsynthesis

LigandPNGBDBM21878(2,9-disubstituted 6-oxopurine, 12b | 9-[4-(diethyl...)
Affinity DataIC50:  230nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101056(2-Biphenyl-2-yl-N-[(2R,3S,5R)-5-(5-ethyl-2,4-dioxo...)
Affinity DataIC50:  240nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101057(10,11-Dihydro-5H-dibenzo[a,d]cycloheptene-5-carbox...)
Affinity DataIC50:  260nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50101052(CHEMBL44535 | N-[(2R,3S,5R)-5-(5-Ethyl-2,4-dioxo-3...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against HSV-1 Thymidine Kinase (HSV-1 TK)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50366681(BRIVUDINE | BVDU | Bridic | Brivox | Brivudin | Br...)
Affinity DataIC50:  300nMAssay Description:Binding affinity towards HSV-1 thymidine kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 2)
Glsynthesis

LigandPNGBDBM21890(2,9-disubstituted 6-oxopurine, 12n | 9-[4-(3-hydro...)
Affinity DataIC50:  310nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 2)
Glsynthesis

LigandPNGBDBM21880(2,9-disubstituted 6-oxopurine, 12d | 9-{4-[bis(2-h...)
Affinity DataIC50:  340nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1 (strain SC16) (HHV-1) (Human h...)
Roche Discovery Welwyn

Curated by ChEMBL
LigandPNGBDBM50013098(2-(3-Chloro-phenylamino)-1,9-dihydro-purin-6-one |...)
Affinity DataIC50:  350nMAssay Description:Inhibition of TdR phosphorylation using thymidine kinase assay for herpes simplex virus type 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1)
Glsynthesis

LigandPNGBDBM21887(2,9-disubstituted 6-oxopurine, 12k | 2-(phenylamin...)
Affinity DataIC50:  350nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 2)
Glsynthesis

LigandPNGBDBM21879(2,9-disubstituted 6-oxopurine, 12c | 9-{4-[ethyl(m...)
Affinity DataIC50:  380nMAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidine kinase(Human herpesvirus 1)
Glsynthesis

LigandPNGBDBM21894(1-{4-[6-oxo-2-(phenylamino)-6,9-dihydro-3H-purin-9...)
Affinity DataIC50:  410nMpH: 7.5 T: 2°CAssay Description:Recombinant HSV TKs were assayed in reaction mixture containing substrate [3H-methyl]TdR and test compounds. After reaction was stopped, the radioact...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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