Compile Data Set for Download or QSAR
(2D       Computed 3D by Vconf -m prep )

Data curated solely by BindingDB

Found 6 hits of affinity data for UniProtKB/TrEMBL: P00491

Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	pH	Temp °C
Purine Nucleoside Phosphorylase (PNP) Homo sapiens (human)	Azetidine based compound, 34 (7-{[3,3-bis(hydroxymethyl)azetidin-1-yl]methyl}-3H...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	0.2290	-54.46	n/a	n/a	n/a	7.7	22
Industrial Research Limited					J Med Chem. 51: 948-56 (2008)
Purine Nucleoside Phosphorylase (PNP) Homo sapiens (human)	DADMe-ImmH,7 (7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CSLS MMDB PC cid PC sid PDB	B.MOAD MMDB PDB PubMed	1.100	-50.61	n/a	n/a	n/a	7.7	22
Industrial Research Limited					J Med Chem. 51: 948-56 (2008)
Purine Nucleoside Phosphorylase (PNP) Homo sapiens (human)	Azetidine based compound, (+/-) 42 (7-{[2-(hydroxymethyl)azetidin-1-yl]methyl}-3H,4H,5...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	1.800	-49.41	n/a	n/a	n/a	7.7	22
Industrial Research Limited					J Med Chem. 51: 948-56 (2008)
Purine Nucleoside Phosphorylase (PNP) Homo sapiens (human)	Azetidine based compound, 35 (7-{[3-(hydroxymethyl)azetidin-1-yl]methyl}-3H,4H,5...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	6.300	-46.33	n/a	n/a	n/a	7.7	22
Industrial Research Limited					J Med Chem. 51: 948-56 (2008)
Purine Nucleoside Phosphorylase (PNP) Homo sapiens (human)	Azetidine based compound, 40 (7-{[(2R,4S)-2,4-bis(hydroxymethyl)azetidin-1-yl]me...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	12.90	-44.57	n/a	n/a	n/a	7.7	22
Industrial Research Limited					J Med Chem. 51: 948-56 (2008)
Purine Nucleoside Phosphorylase (PNP) Homo sapiens (human)	Azetidine based compound, (+/-) 41 (7-{[(2R,4R)-2,4-bis(hydroxymethyl)azetidin-1-yl]me...)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	280.0	-37.02	n/a	n/a	n/a	7.7	22
Industrial Research Limited					J Med Chem. 51: 948-56 (2008)

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• Change energy unit to:  kcal/mole