BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 3 hits of non-affinity data for polymerid = 2248,2249,2250   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Asparaginyl Endopeptidase (AE)


(Schistosoma mansoni)
BDBM22117
PNG
(aza-peptide Michael acceptor, 5a | benzyl N-[(1S)-...)
Show SMILES CCN(CC)C(=O)C=CC(=O)N(CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)OCc1ccccc1
Show InChI InChI=1S/C24H34N6O7/c1-5-29(6-2)20(32)12-13-21(33)30(14-19(25)31)28-23(35)17(4)26-22(34)16(3)27-24(36)37-15-18-10-8-7-9-11-18/h7-13,16-17H,5-6,14-15H2,1-4H3,(H2,25,31)(H,26,34)(H,27,36)(H,28,35)/t16-,17-/m0/s1
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a6.822



Georgia Institute of Technology



Assay Description
AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...


J Med Chem 51: 2816-32 (2008)

More data for this
Ligand-Target Pair
Asparaginyl Endopeptidase (AE)


(Schistosoma mansoni)
BDBM22132
PNG
(aza-peptide Michael acceptor, 7d | benzyl N-[(1S)-...)
Show SMILES CC=CC=CC(=O)N(CC(N)=O)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)OCc1ccccc1
Show InChI InChI=1S/C22H29N5O6/c1-4-5-7-12-19(29)27(13-18(23)28)26-21(31)16(3)24-20(30)15(2)25-22(32)33-14-17-10-8-6-9-11-17/h4-12,15-16H,13-14H2,1-3H3,(H2,23,28)(H,24,30)(H,25,32)(H,26,31)/t15-,16-/m0/s1
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a6.822



Georgia Institute of Technology



Assay Description
AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...


J Med Chem 51: 2816-32 (2008)

More data for this
Ligand-Target Pair
Asparaginyl Endopeptidase (AE)


(Schistosoma mansoni)
BDBM22131
PNG
(aza-peptide Michael acceptor, 7c | benzyl N-[(1S)-...)
Show SMILES C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](C)C(=O)NN(CC(N)=O)C(=O)C=CC(=O)c1ccccc1
Show InChI InChI=1S/C26H29N5O7/c1-17(29-26(37)38-16-19-9-5-3-6-10-19)24(35)28-18(2)25(36)30-31(15-22(27)33)23(34)14-13-21(32)20-11-7-4-8-12-20/h3-14,17-18H,15-16H2,1-2H3,(H2,27,33)(H,28,35)(H,29,37)(H,30,36)/t17-,18-/m0/s1
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a6.822



Georgia Institute of Technology



Assay Description
AE activity in the induction medium was measured with the substrate Cbz-Ala-Ala-Asn-AMC. In a black 96-well microtiter plate, aza-peptidyl inhibitors...


J Med Chem 51: 2816-32 (2008)

More data for this
Ligand-Target Pair