BindingDB PrimarySearch

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50241050(2-(6-fluoro-1H-indol-3-yl)ethanamine | 6-fluorotry...)

EC50: 4.40nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50025219(CHEMBL3330643)

EC50: 8nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM30853(2-(5-fluoranyl-1H-indol-3-yl)ethanamine;hydrochlor...)

EC50: 10nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50025197(CHEMBL96816)

EC50: 14nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50025221(CHEMBL1906905)

EC50: 16nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50331286(2-(5-chloro-1H-indol-3-yl)ethanamine | 5-Cl-T | CH...)

EC50: 19nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

Purchase CHEMBL PC cid PC sid PDB Patents Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50025214(CHEMBL3330640)

EC50: 19nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50025200(CHEMBL3330645)

EC50: 20nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50014210(1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...)

EC50: 22nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

Purchase ChEBI
CHEMBL DrugBank PC cid PC sid PDB Patents Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM30701(2-(1H-indol-3-yl)-N-methyl-ethanamine | 2-(1H-indo...)

EC50: 22nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

Purchase ChEBI
KEGG PC cid PC sid PDB Patents Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50025198(Etryptamine)

EC50: 23nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

Purchase DrugBank PC cid PC sid Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50025218(CHEMBL204839)

EC50: 24nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50025222(CHEMBL3330647)

EC50: 33nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50024210(1H-indole-3-ethanamine | 2-(1H-indol-3-yl)ethanami...)

EC50: 33nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

Purchase ChEBI
CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB Patents Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50025212(CHEMBL3330646)

EC50: 35nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50025213(CHEMBL3330648)

EC50: 37nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50236720(CHEMBL4104749)

EC50: 41nMAssay Description:Antagonist activity against human progesterone receptor (hPR) using cotransfection assay in CV-1 cellsMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50025220(CHEMBL3330644)

EC50: 45nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50025217(CHEMBL3330642)

EC50: 52nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50025215(CHEMBL3330641)

EC50: 53nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

Purchase CHEMBL PC cid PC sid PDB Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50028124(2-(6-Methoxy-1H-indol-3-yl)-ethylamine | 2-(6-meth...)

EC50: 54nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

Purchase CHEMBL PC cid PC sid PDB Patents Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50025200(CHEMBL3330645)

EC50: 55nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50010588((RS)-3,4-(methylenedioxy)methamphetamine | 1-(1,3-...)

EC50: 61nMAssay Description:Binding affinity to SERT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]5-HT release by liquid scintillation counting methodMore data for this Ligand-Target Pair

Purchase ChEBI
CHEMBL DrugBank KEGG PC cid PC sid PDB Patents Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50025212(CHEMBL3330646)

EC50: 68nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50010588((RS)-3,4-(methylenedioxy)methamphetamine | 1-(1,3-...)

EC50: 72nMAssay Description:Compound was tested for its ability to inhibit high affinity uptake of [3H]5-HT into mid brain nerve endings (synaptosomes) in ratMore data for this Ligand-Target Pair

Purchase ChEBI
CHEMBL DrugBank KEGG PC cid PC sid PDB Patents Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM85332(MDMA, R(-))

EC50: 74nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair

Purchase ChEBI
KEGG MMDB PC cid PC sid PDB Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50331288(2-(5-bromo-1H-indol-3-yl)ethanamine | 5-Br-T | CHE...)

EC50: 75nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50114074(CHEMBL3603955)

EC50: 91nMAssay Description:Binding affinity to SERT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]5-HT release by liquid scintillation counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM86238(CAS_3050061 | MDA,S(+) | NSC_3050061)

EC50: 100nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair

Purchase PC cid PC sid Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50025216(CHEMBL382635)

EC50: 108nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM84738(CAS_16105-77-4 | Fenfluramine | Fenfluramine (+) |...)

EC50: 108nMAssay Description:Binding affinity against human progesterone receptor (hPR) in a competitive binding assayMore data for this Ligand-Target Pair

Purchase ChEBI
DrugBank KEGG PC cid PC sid Patents Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50114072(CHEMBL3603954)

EC50: 117nMAssay Description:Binding affinity to SERT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]5-HT release by liquid scintillation counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50029103(2-(3-Chloro-phenyl)-1-methyl-ethylamine | CHEMBL14...)

EC50: 120nMAssay Description:Induction of SERT-mediated serotonin release in rat synaptosomesMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50236728(CHEMBL4086874)

EC50: 134nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50073691(2-(5-Methyl-1H-indol-3-yl)-ethylamine | 5-Methyl-t...)

EC50: 139nMAssay Description:Induction of 5-HTT-mediated 5-HT release in rat brain synaptosomes by [3H]5-HT release assayMore data for this Ligand-Target Pair

Purchase CHEMBL PC cid PC sid PDB Patents Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50005247((+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine |...)

EC50: 160nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair

Purchase CHEMBL DrugBank PC cid PC sid Patents Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50023177(CHEMBL3298871)

EC50: 181nMAssay Description:Induction of SERT-mediated serotonin release in rat synaptosomesMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50114073(CHEMBL3604010)

EC50: 242nMAssay Description:Binding affinity to SERT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]5-HT release by liquid scintillation counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM86239(CAS_3046161 | MDA,R(-) | NSC_3046161)

EC50: 310nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair

Purchase PC cid PC sid Patents Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM86234(CAS_64057-70-1 | MDMA,S(+) | NSC_126235)

EC50: 340nMAssay Description:Activity at SERT in rat synaptosomes assessed as release of [3H]HT after 5 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair

Purchase ChEBI
KEGG PC cid PC sid Similars

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50114071(CHEMBL3604009)

EC50: 347nMAssay Description:Binding affinity to SERT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]5-HT release by liquid scintillation counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50023161(CHEMBL3298870)

EC50: 356nMAssay Description:Induction of SERT-mediated serotonin release in rat synaptosomesMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50023178(CHEMBL3298873)

EC50: 410nMAssay Description:Induction of SERT-mediated serotonin release in rat synaptosomesMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50023162(CHEMBL3298862)

EC50: 562nMAssay Description:Induction of SERT-mediated serotonin release in rat synaptosomesMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50114075(CHEMBL3603956)

EC50: 573nMAssay Description:Binding affinity to SERT in Sprague-Dawley rat brain synaptosomes assessed as induction of [3H]5-HT release by liquid scintillation counting methodMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50023165(CHEMBL3298865)

EC50: 621nMAssay Description:Induction of SERT-mediated serotonin release in rat synaptosomesMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50023176(CHEMBL3298869)

EC50: 667nMAssay Description:Induction of SERT-mediated serotonin release in rat synaptosomesMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50023163(CHEMBL3298863)

EC50: 733nMAssay Description:Induction of SERT-mediated serotonin release in rat synaptosomesMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar

Sodium-dependent serotonin transporter(Rattus norvegicus (rat))
Research Triangle Institute

Curated by ChEMBL

BDBM50023174(CHEMBL3298867)

EC50: 1.01E+3nMAssay Description:Induction of SERT-mediated serotonin release in rat synaptosomesMore data for this Ligand-Target Pair

CHEMBL PC cid PC sid Patents Similars