Compile Data Set for Download or QSAR
maximum 50k data
Found 4 of ic50 for UniProtKB: Q91ZY2
TargetHistamine H4 receptor(Mus musculus (mouse))
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM22566(5-chloro-2-[(4-methylpiperazin-1-yl)carbonyl]-1H-i...)
Affinity DataIC50:  40nMAssay Description:Inhibition of histamine H4 receptor-mediated chemotaxis in mouse bone marrow cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Mus musculus (mouse))
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM50538677(CHEMBL4635634)
Affinity DataIC50:  83nMAssay Description:Inverse agonist activity at mouse H4R expressed in HEK293-SF-mH4R-His6-CRE-Luc cells assessed as reduction in histamine-induced inhibition of forskol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Mus musculus (mouse))
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM294407(US9586959, Compound 69 | US9586959, Compound 95)
Affinity DataIC50:  290nMAssay Description:Displacement of [3H]-histamine from recombinant mouse histamine H4 receptor expressed in CHO-K1 cell membranes measured after 30 mins by microbeta sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H4 receptor(Mus musculus (mouse))
Boehringer Ingelheim Rcv

Curated by ChEMBL
LigandPNGBDBM294407(US9586959, Compound 69 | US9586959, Compound 95)
Affinity DataIC50:  690nMAssay Description:Antagonist activity at recombinant mouse histamine H4 receptor expressed in CHO-K1 cells assessed as inhibition of R-alpha-methylhistamine induced st...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed