Affinity DataEC50: 0.220nMAssay Description:In vitro intrinsic activity against histamine H3 receptor from synaptosomes of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataEC50: 0.25nMAssay Description:In vitro intrinsic activity against histamine H3 receptor from synaptosomes of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataEC50: 0.550nMAssay Description:In vitro intrinsic activity against histamine H3 receptor from synaptosomes of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataEC50: 0.740nMAssay Description:Agonist activity at rat histamine H3 receptor expressed in HEK239 cells assessed as reduction of basal [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:The compound was evaluated for agonistic effect on release of [3H]-histamine from rat brain cortical slices with L-[3H]-histidine at 0.3 microMMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:In vitro intrinsic activity against histamine H3 receptor from synaptosomes of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Inverse agonist activity at rat histamine H3 receptor assessed as inhibition of R-alpha-methylhistamine induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 2.10nMAssay Description:Inverse agonist activity at rat histamine H3 receptor assessed as inhibition of R-alpha-methylhistamine induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 2.20nMAssay Description:Inverse agonist activity at rat histamine H3 receptor assessed as inhibition of R-alpha-methylhistamine induced [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 2.80nMAssay Description:In vitro binding affinity against histamine H3 receptor from synaptosomes of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataEC50: 3.02nMAssay Description:Agonist activity at rat histamine H3 receptor expressed in HEK239 cells assessed as reduction of basal [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 3.63nMAssay Description:Agonist activity at rat histamine H3 receptor expressed in HEK239 cells assessed as reduction of basal [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Compound was evaluated for agonistic effect on release of [3H]-histamine from rat brain cortical slices with L-[3H]-histidine at 0.3 microMMore data for this Ligand-Target Pair
Affinity DataEC50: 5.01nMAssay Description:Agonist activity at rat histamine H3 receptor expressed in HEK239 cells assessed as reduction of basal [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 5.75nMAssay Description:Agonist activity at rat histamine H3 receptor expressed in HEK239 cells assessed as reduction of basal [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 7.24nMAssay Description:Agonist activity at rat histamine H3 receptor expressed in HEK239 cells assessed as reduction of basal [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:The compound was evaluated for agonistic effect on release of [3H]-histamine from rat brain cortical slices with L-[3H]-histidine at 0.3 microMMore data for this Ligand-Target Pair
Affinity DataEC50: 17.4nMAssay Description:Agonist activity at rat histamine H3 receptor expressed in HEK239 cells assessed as reduction of basal [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Inverse agonist activity at rat histamine H3 receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 45nMAssay Description:In vitro binding affinity against histamine H3 receptor from synaptosomes of rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataEC50: 62nMAssay Description:Compound was evaluated for antagonistic effect on release of [3H]-histamine from rat brain cortical slices with L-[3H]-histidine at 0.3 microMMore data for this Ligand-Target Pair
Affinity DataEC50: 128nMAssay Description:In vitro binding affinity against histamine H3 receptor from synaptosomes of rat cerebral cortexMore data for this Ligand-Target Pair