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| Target (Institution) | Ligand | Target Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|
| IMP Cyclohydrolase (IMPCH) Homo sapiens (human) | Heterocycle, 1![]() (1H,3H,4H,7H-2$l^{6},1,3,5,7-imidazo[4,5-c][1,2,6]t...) | B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt | CSLS PC cid PC sid PDB | PubMed | 130.0 | -38.90 | n/a | n/a | n/a | 7.4 | 22 |
The Scripps Research Institute | J Biol Chem. 282: 13033-46 (2007) | ||||||||||
| IMP Cyclohydrolase (IMPCH) Homo sapiens (human) | Nucleotide, 3![]() ({[(2R,3S,4R,5R)-3,4-dihydroxy-5-(2,2,4-trioxo-1H,3...) | B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt | CSLS MMDB PC cid PC sid PDB | PubMed | 150.0 | -38.55 | n/a | n/a | n/a | 7.4 | 22 |
The Scripps Research Institute | J Biol Chem. 282: 13033-46 (2007) | ||||||||||
| IMP Cyclohydrolase (IMPCH) Homo sapiens (human) | Nucleoside, 2![]() (7-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)ox...) | B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt | CSLS MMDB PC cid PC sid PDB | PubMed | 230.0 | -37.50 | n/a | n/a | n/a | 7.4 | 22 |
The Scripps Research Institute | J Biol Chem. 282: 13033-46 (2007) | ||||||||||