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Found 426 of ic50 for UniProtKB: P07195
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597915(CHEMBL5185237)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597915(CHEMBL5185237)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597916(CHEMBL5201115)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597916(CHEMBL5201115)
Affinity DataIC50:  2.20nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597908(CHEMBL5181496)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597908(CHEMBL5181496)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM197160(GNE-140 (6))
Affinity DataIC50:  5nMAssay Description:LDHA, LDHB, LDHC, MDH1 and MDH2 enzymatic assays have been described in detail previously [Dragovich, P.S. et al, Bioorg. Med. Chem. Lett. 24:3764-37...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM197160(GNE-140 (6))
Affinity DataIC50:  5nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50250655(CHEMBL4059985 | US10961200, Compound 189 | US11247...)
Affinity DataIC50:  8nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597909(CHEMBL5196929)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597909(CHEMBL5196929)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597898(CHEMBL5172378)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597898(CHEMBL5172378)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597913(CHEMBL5194549)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597913(CHEMBL5194549)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597906(CHEMBL5183539)
Affinity DataIC50:  9.80nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597896(CHEMBL5181996)
Affinity DataIC50:  15nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597896(CHEMBL5181996)
Affinity DataIC50:  15nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597905(CHEMBL5182266)
Affinity DataIC50:  17nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597905(CHEMBL5182266)
Affinity DataIC50:  17nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50250653(CHEMBL4090677 | US10961200, Compound 46 | US112479...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50250677(CHEMBL4100845 | US10961200, Compound 52 | US112479...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597914(CHEMBL5188480)
Affinity DataIC50:  25nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597914(CHEMBL5188480)
Affinity DataIC50:  25nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50250656(CHEMBL4081890 | US11247971, Cmpd ID 276)
Affinity DataIC50:  27nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50534334(CHEMBL4436150)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597910(CHEMBL5202219)
Affinity DataIC50:  34nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597910(CHEMBL5202219)
Affinity DataIC50:  34nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50534318(CHEMBL4576717)
Affinity DataIC50:  35nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50534309(CHEMBL4467769)
Affinity DataIC50:  35nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50103568(CHEMBL3335794)
Affinity DataIC50:  43nMAssay Description:Competitive inhibition of human LDH1 in presence of NADHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50534335(CHEMBL4536094)
Affinity DataIC50:  46nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597907(CHEMBL5189879)
Affinity DataIC50:  46nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597902(CHEMBL5177632)
Affinity DataIC50:  47nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50250648(CHEMBL4080497 | US10961200, Compound 20 | US112479...)
Affinity DataIC50:  49nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50534330(CHEMBL4520899)
Affinity DataIC50:  49nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50534323(CHEMBL4444963)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50534316(CHEMBL4453059)
Affinity DataIC50:  55nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597912(CHEMBL5196259)
Affinity DataIC50:  57nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50534329(CHEMBL4521960)
Affinity DataIC50:  57nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597912(CHEMBL5196259)
Affinity DataIC50:  57nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50534331(CHEMBL4475593)
Affinity DataIC50:  60nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50250652(CHEMBL4101800 | US10961200, Compound 42 | US112479...)
Affinity DataIC50:  62nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597904(CHEMBL5176448)
Affinity DataIC50:  65nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597904(CHEMBL5176448)
Affinity DataIC50:  65nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50534307(CHEMBL4543949)
Affinity DataIC50:  70nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597895(CHEMBL5189798)
Affinity DataIC50:  75nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50534306(CHEMBL4450897)
Affinity DataIC50:  75nMAssay Description:Inhibition of human recombinant carboxy-terminal His-tagged LDHB by UV endpoint assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50597903(CHEMBL5197729)
Affinity DataIC50:  75nMAssay Description:Inhibition of LDHB (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetL-lactate dehydrogenase B chain(Homo sapiens (Human))
Genentech

Curated by ChEMBL
LigandPNGBDBM50250667(CHEMBL4075666 | US10961200, Compound 40 | US112479...)
Affinity DataIC50:  75nMAssay Description:Inhibition of human erythrocytes LDHB using sodium pyruvate as substrate after 5 mins in presence of NAPDH by diaphorase/resazurin based fluorescence...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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