PrimarySearch

Found 11 hits affinity hit(s) for enzyme = Matrix Metalloproteinase-14 (MMP-14) with UniProtKB: P50281
Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	pH	Temp °C
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	TMI-1 ((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...)	GoogleScholar MMDB PDB UniProtKB/SwissProt	B.MOAD CSLS PDB PubChem	PubMed	n/a	n/a	26.0	n/a	n/a	7.4	22
Wyeth Research		GoogleScholar MMDB PDB UniProtKB/SwissProt	B.MOAD CSLS PDB PubChem	PubMed	J Pharmacol Exp Ther. 309: 348-55 (2004)
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	beta-sulfonyl hydroxamate analogue, 20 (4-({[4-(but-2-yn-1-ylamino)benzene]sulfonyl}methyl...)	GoogleScholar MMDB PDB UniProtKB/SwissProt	PubChem	PubMed	n/a	n/a	1000.0	n/a	n/a	7.4	22
Wyeth Research		GoogleScholar MMDB PDB UniProtKB/SwissProt	PubChem	PubMed	Bioorg Med Chem. 15: 6170-81 (2007)
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	beta-sulfonyl hydroxamate analogue, 7 (tert-butyl 4-({[4-(but-2-yn-1-ylamino)benzene]sulf...)	GoogleScholar MMDB PDB UniProtKB/SwissProt	PDB PubChem	PubMed	n/a	n/a	2370.0	n/a	n/a	7.4	22
Wyeth Research		GoogleScholar MMDB PDB UniProtKB/SwissProt	PDB PubChem	PubMed	Bioorg Med Chem. 15: 6170-81 (2007)
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	biphenylsulfonamide carboxylate, 24 ((2R)-3-methyl-2-[(4-{4-[(3-methyl-1-benzofuran-2-y...)	GoogleScholar MMDB PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	n/a	n/a	3000.0	n/a	n/a	7.5	22
Wyeth Research		GoogleScholar MMDB PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	Bioorg Med Chem Lett. 16: 311-6 (2006)
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	beta-sulfonyl hydroxamate analogue, 19 (4-({[4-(but-2-yn-1-ylamino)benzene]sulfonyl}methyl...)	GoogleScholar MMDB PDB UniProtKB/SwissProt	PubChem	PubMed	n/a	n/a	3619.0	n/a	n/a	7.4	22
Wyeth Research		GoogleScholar MMDB PDB UniProtKB/SwissProt	PubChem	PubMed	Bioorg Med Chem. 15: 6170-81 (2007)
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	beta-sulfonyl hydroxamate analogue, 4 (4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)	GoogleScholar MMDB PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	n/a	n/a	3642.0	n/a	n/a	7.4	22
Wyeth Research		GoogleScholar MMDB PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	Bioorg Med Chem. 15: 6170-81 (2007)
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	beta-sulfonyl hydroxamate analogue, 18 (4-({[4-(but-2-yn-1-ylamino)benzene]sulfonyl}methyl...)	GoogleScholar MMDB PDB UniProtKB/SwissProt	PubChem	PubMed	n/a	n/a	4320.0	n/a	n/a	7.4	22
Wyeth Research		GoogleScholar MMDB PDB UniProtKB/SwissProt	PubChem	PubMed	Bioorg Med Chem. 15: 6170-81 (2007)
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	beta-sulfonyl hydroxamate analogue, 22 (4-({[4-(but-2-yn-1-ylamino)benzene]sulfonyl}methyl...)	GoogleScholar MMDB PDB UniProtKB/SwissProt	PubChem	PubMed	n/a	n/a	4891.0	n/a	n/a	7.4	22
Wyeth Research		GoogleScholar MMDB PDB UniProtKB/SwissProt	PubChem	PubMed	Bioorg Med Chem. 15: 6170-81 (2007)
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	beta-sulfonyl hydroxamate analogue, 21 (4-({[4-(but-2-yn-1-ylamino)benzene]sulfonyl}methyl...)	GoogleScholar MMDB PDB UniProtKB/SwissProt	PubChem	PubMed	n/a	n/a	7047.0	n/a	n/a	7.4	22
Wyeth Research		GoogleScholar MMDB PDB UniProtKB/SwissProt	PubChem	PubMed	Bioorg Med Chem. 15: 6170-81 (2007)
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	thiopyranothienopyrimidine, 1 (N-{[2-(2-amino-3,4-dioxocyclobut-1-en-1-yl)-1,2,3,...)	GoogleScholar MMDB PDB UniProtKB/SwissProt	PDB PubChem	PubMed	n/a	n/a	>10000.0	n/a	n/a	7.5	22
Istituto di CristallografiaCNR		GoogleScholar MMDB PDB UniProtKB/SwissProt	PDB PubChem	PubMed	J Med Chem. (2009)
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	hexahydrobenzothienopyrimidine, 2 (13-(carbamoylmethyl)-3-oxo-N-[(3-oxo-3,4-dihydro-2...)	GoogleScholar MMDB PDB UniProtKB/SwissProt	PDB PubChem	PubMed	n/a	n/a	>10000.0	n/a	n/a	7.5	22
Istituto di CristallografiaCNR		GoogleScholar MMDB PDB UniProtKB/SwissProt	PDB PubChem	PubMed	J Med Chem. (2009)

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Change energy unit to: kcal/mole