Compile Data Set for Download or QSAR
(2D       Computed 3D by Vconf -m prep )

Data curated solely by BindingDB

Found 11 hits of affinity data for UniProtKB/TrEMBL: P50281

Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	pH	Temp °C
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	TMI-1 ((3S)-4-{[4-(but-2-yn-1-yloxy)benzene]sulfonyl}-N-h...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	B.MOAD CHEBI CSLS MMDB PC cid PC sid PDB	PubMed	n/a	n/a	26.0	n/a	n/a	7.4	22
Wyeth Research					J Pharmacol Exp Ther. 309: 348-55 (2004)
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	beta-sulfonyl hydroxamate analogue, 20 (4-({[4-(but-2-yn-1-ylamino)benzene]sulfonyl}methyl...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	1000.0	n/a	n/a	7.4	22
Wyeth Research					Bioorg Med Chem. 15: 6170-81 (2007)
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	beta-sulfonyl hydroxamate analogue, 7 (tert-butyl 4-({[4-(but-2-yn-1-ylamino)benzene]sulf...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	MMDB PC cid PC sid PDB	PubMed	n/a	n/a	2370.0	n/a	n/a	7.4	22
Wyeth Research					Bioorg Med Chem. 15: 6170-81 (2007)
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	biphenylsulfonamide carboxylate, 24 ((2R)-3-methyl-2-[(4-{4-[(3-methyl-1-benzofuran-2-y...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	n/a	n/a	3000.0	n/a	n/a	7.5	22
Wyeth Research					Bioorg Med Chem Lett. 16: 311-6 (2006)
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	beta-sulfonyl hydroxamate analogue, 19 (4-({[4-(but-2-yn-1-ylamino)benzene]sulfonyl}methyl...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	3619.0	n/a	n/a	7.4	22
Wyeth Research					Bioorg Med Chem. 15: 6170-81 (2007)
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	beta-sulfonyl hydroxamate analogue, 4 (4-({[4-(but-2-yn-1-yloxy)benzene]sulfonyl}methyl)-...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS PC cid PC sid	PubMed	n/a	n/a	3642.0	n/a	n/a	7.4	22
Wyeth Research					Bioorg Med Chem. 15: 6170-81 (2007)
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	beta-sulfonyl hydroxamate analogue, 18 (4-({[4-(but-2-yn-1-ylamino)benzene]sulfonyl}methyl...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	4320.0	n/a	n/a	7.4	22
Wyeth Research					Bioorg Med Chem. 15: 6170-81 (2007)
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	beta-sulfonyl hydroxamate analogue, 22 (4-({[4-(but-2-yn-1-ylamino)benzene]sulfonyl}methyl...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	4891.0	n/a	n/a	7.4	22
Wyeth Research					Bioorg Med Chem. 15: 6170-81 (2007)
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	beta-sulfonyl hydroxamate analogue, 21 (4-({[4-(but-2-yn-1-ylamino)benzene]sulfonyl}methyl...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid	PubMed	n/a	n/a	7047.0	n/a	n/a	7.4	22
Wyeth Research					Bioorg Med Chem. 15: 6170-81 (2007)
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	hexahydrobenzothienopyrimidine, 2 (13-(carbamoylmethyl)-3-oxo-N-[(3-oxo-3,4-dihydro-2...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	PC cid PC sid PDB	PubMed	n/a	n/a	>10000.0	n/a	n/a	7.5	22
Universita degli Studi					J Med Chem. 52: 1040-9 (2009)
Matrix Metalloproteinase-14 (MMP-14) Homo sapiens (human)	thiopyranothienopyrimidine, 1 (N-{[2-(2-amino-3,4-dioxocyclobut-1-en-1-yl)-1,2,3,...)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	MMDB PC cid PC sid PDB	PubMed	n/a	n/a	>10000.0	n/a	n/a	7.5	22
Universita degli Studi					J Med Chem. 52: 1040-9 (2009)

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• Change energy unit to:  kcal/mole