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Compile Data Set for Download or QSAR

Found 3 hits of ic50 data for polymerid = 256   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Eukaryotic initiation factor 4A-III


(Human)
BDBM65493
PNG
(eIF4A3 inhibitor, 2)
Show SMILES Clc1ccc(cc1)[C@H]1CN(CCN1C(=O)c1ccc(Br)cc1)C(=O)c1cnn2cc(Br)ccc12
Show InChI InChI=1/C25H19Br2ClN4O2/c26-18-5-1-17(2-6-18)24(33)31-12-11-30(15-23(31)16-3-8-20(28)9-4-16)25(34)21-13-29-32-14-19(27)7-10-22(21)32/h1-10,13-14,23H,11-12,15H2/t23-/s2
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 110n/an/an/an/an/an/a



BC Cancer Agency



Assay Description
Inhibitory activity was assessed under the following conditions: 350 uM ATP/1.5 ug mL−1 RNA indicated by black; 35 uM ATP/1.5 ug mL−1 RNA...


ACS Chem Biol 12: 1760-1768 (2017)

More data for this
Ligand-Target Pair
Eukaryotic initiation factor 4A-III


(Human)
BDBM65492
PNG
(eIF4A3 inhibitor, 1)
Show SMILES Clc1ccc(cc1)C1CN(CCN1C(=O)c1ccc(Cl)cc1)C(=O)c1cnc(o1)-c1ccccc1
Show InChI InChI=1/C27H21Cl2N3O3/c28-21-10-6-18(7-11-21)23-17-31(14-15-32(23)26(33)20-8-12-22(29)13-9-20)27(34)24-16-30-25(35-24)19-4-2-1-3-5-19/h1-13,16,23H,14-15,17H2
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.20E+3n/an/an/an/an/an/a



BC Cancer Agency



Assay Description
Inhibitory activity was assessed under the following conditions: 350 uM ATP/1.5 ug mL−1 RNA indicated by black; 35 uM ATP/1.5 ug mL−1 RNA...


ACS Chem Biol 12: 1760-1768 (2017)

More data for this
Ligand-Target Pair
Eukaryotic initiation factor 4A-III


(Human)
BDBM65494
PNG
(eIF4A3 inhibitor, 3)
Show SMILES Clc1ccc(cc1)[C@@H]1CN(CCN1C(=O)c1ccc(Br)cc1)C(=O)c1cnn2cc(Br)ccc12
Show InChI InChI=1/C25H19Br2ClN4O2/c26-18-5-1-17(2-6-18)24(33)31-12-11-30(15-23(31)16-3-8-20(28)9-4-16)25(34)21-13-29-32-14-19(27)7-10-22(21)32/h1-10,13-14,23H,11-12,15H2/t23-/s2
PDB
MMDB

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.00E+4n/an/an/an/an/an/a



BC Cancer Agency



Assay Description
Inhibitory activity was assessed under the following conditions: 350 uM ATP/1.5 ug mL−1 RNA indicated by black; 35 uM ATP/1.5 ug mL−1 RNA...


ACS Chem Biol 12: 1760-1768 (2017)

More data for this
Ligand-Target Pair