Compile Data Set for Download or QSAR
maximum 50k data
Found 711 of ic50 data for polymerid = 2645,50006778
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM162865(US9056843, 156)
Affinity DataIC50:  1nMAssay Description:Inhibition of recombinant human HDAC7 using fluorogenic substrate by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50: >1nMAssay Description:Inhibition of HDAC7More data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50258539((S)-1-methyl-N-(1-(5-(naphthalen-2-yl)-1H-imidazol...)
Affinity DataIC50: >1nMAssay Description:Inhibition of HDAC7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM25146(2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...)
Affinity DataIC50: >1nMAssay Description:Inhibition of HDAC7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50268063((E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-(7-quinoliny...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant HDAC7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant full length human HDAC7 expressed in baculovirus infected Sf9 cells using FAM-RHKK-TFAc as substrate incubated for 3 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataIC50:  4nMAssay Description:Inhibition of recombinant full length human HDAC7 expressed in SF9 baculovirus using FAM- labelled acetylated peptide as substrate measured by Electr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50268042((2E,4E)-N-[6-(Hydroxyamino)-6-oxohexyl]-3-methyl-5...)
Affinity DataIC50:  4.40nMAssay Description:Inhibition of human recombinant HDAC7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM19428((2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol...)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of human HDAC7 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50268121((E)-3-(4-Chloro-2-fluorophenyl)-N-[6-(hydroxyamino...)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of human recombinant HDAC7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50563276(CHEMBL4751615)
Affinity DataIC50:  7.70nMAssay Description:Inhibition of recombinant human HDAC7 using fluorogenic substrate by fluorescence microplate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataIC50:  8.20nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)
Affinity DataIC50:  10nMAssay Description:Inhibition of HDAC7 (unknown origin) using acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin as substrate after 15 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM162846(US9056843, 137)
Affinity DataIC50:  10nMAssay Description:Inhibition of HDAC7 (unknown origin) using Boc Lys(TFA) as substrate by fluorogenic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50581678(CHEMBL5072502)
Affinity DataIC50: >10nMAssay Description:Inhibition of recombinant HDAC7 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate pre-incubated for 1 hr followed by substrate additio...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)
Affinity DataIC50: >10nMAssay Description:Inhibition of recombinant human HDAC7 using pan-HDAC substrate incubated for 3 hrs by fluorescence methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50563273(CHEMBL4748500)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human HDAC7 using Ac-LGK(TFA)-AMC as substrate pre-incubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50563275(CHEMBL4761013)
Affinity DataIC50:  12nMAssay Description:Inhibition of recombinant human HDAC7 using Ac-LGK(TFA)-AMC as substrate pre-incubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM162846(US9056843, 137)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant HDAC7 (unknown origin) using Boc-Lys(TFA)-AMC as substrate by fluorescence based plate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50568248(CHEMBL4879105)
Affinity DataIC50:  16nMAssay Description:Inhibition of N-terminal GST-tagged human HDAC7 (518 to end residues) expressed in baculovirus-infected Sf9 cells assessed as reduction in 7-amino-4-...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50552915(CHEMBL4798111)
Affinity DataIC50:  20nMAssay Description:Inhibition of HDAC7 (unknown origin) using Boc Lys(TFA) as substrate by fluorogenic assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human HDAC7More data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  22nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM19130((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human HDAC7 by fluorimetric assayMore data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50503692(CHEMBL4437833)
Affinity DataIC50:  23nMAssay Description:Inhibition of human N-terminal GST-tagged HDAC7 (518 to end residues) expressed in baculovirus infected Sf9 insect cells using Boc-Lys-TFA as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50005711(CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human HDAC7 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50563274(CHEMBL4799406)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant human HDAC7 using Ac-LGK(TFA)-AMC as substrate pre-incubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50188961(CHEMBL3622533)
Affinity DataIC50:  27nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50563276(CHEMBL4751615)
Affinity DataIC50:  27nMAssay Description:Inhibition of recombinant human HDAC7 using Ac-LGK(TFA)-AMC as substrate pre-incubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50333088((S)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human HDAC7 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50252391(CHEMBL4080014)
Affinity DataIC50:  30nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50380399(CHEMBL2018302 | Tubastatin A | US10227295, Compoun...)
Affinity DataIC50: >30nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50563286(CHEMBL4776127)
Affinity DataIC50:  31nMAssay Description:Inhibition of recombinant human HDAC7 using Ac-LGK(TFA)-AMC as substrate pre-incubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50503690(CHEMBL4456445)
Affinity DataIC50:  31nMAssay Description:Inhibition of recombinant HDAC7 (unknown origin) using Boc-Lys(TFA)-AMC as substrate by fluorescence based plate reader assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50503690(CHEMBL4456445)
Affinity DataIC50:  31nMAssay Description:Inhibition of human N-terminal GST-tagged HDAC7 (518 to end residues) expressed in baculovirus infected Sf9 insect cells using Boc-Lys-TFA as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM19422(4-(acetylamino)-N-(2-amino-phenyl) benzamide | CI-...)
Affinity DataIC50: >33nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged HDAC7 (518 to 991 residues) expressed in insect cells using RHK-K(Ac)-AMC as substrate incubate...More data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human HDAC7 using fluorogenic tetrapeptide RHKKAc as substrateMore data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM531084(US11207431, Example C)
Affinity DataIC50:  36nMAssay Description:IC50 measurements were conducted by BPS Biosciences (Table 1) or by Nanosyn (Table 1A) with an established fluorescence assay. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)
Affinity DataIC50:  40.9nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged HDAC7 (518 to 991 residues) expressed in insect cells using Boc-K(TFA)-AMC as substrate incubat...More data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50304782(CHEMBL609583 | N-hydroxy-2-(4-(naphthalen-2-ylsulf...)
Affinity DataIC50:  46nMAssay Description:Inhibition of human HDAC7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50563285(CHEMBL4762512)
Affinity DataIC50:  49nMAssay Description:Inhibition of recombinant human HDAC7 using Ac-LGK(TFA)-AMC as substrate pre-incubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50300446(CHEMBL583490 | N-hydroxy-9H-xanthene-9-carboxamide)
Affinity DataIC50:  50nMAssay Description:Inhibition of human recombinant N-terminal FLAG-tagged HDAC7 (438-915) expressed in baculovirus after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50574023(CHEMBL4874942)
Affinity DataIC50:  50nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50446481(CHEMBL3110004 | US10011611, TMP269 | US10722597, C...)
Affinity DataIC50:  60nMAssay Description:Inhibition of HDAC7 (unknown origin)More data for this Ligand-Target Pair
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50527602(CHEMBL4581057)
Affinity DataIC50:  60nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged HDAC7 (518 to 991 residues) expressed in baculovirus infected insect cells using fluorogenic HD...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50333093((S)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyclo...)
Affinity DataIC50:  61nMAssay Description:Inhibition of human HDAC7 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50446482(CHEMBL3110003)
Affinity DataIC50:  70nMAssay Description:Inhibition of human N-terminal GST-tagged HDAC7 (518 to end residues) expressed in baculovirus infected Sf9 insect cells using Boc-Lys-TFA as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM50333087((R/S)-6-(19-Methoxy-11-oxo-3,13-dioxa-10-azatricyc...)
Affinity DataIC50:  73nMAssay Description:Inhibition of human HDAC7 by fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 7(Homo sapiens (Human))
Stony Brook University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  75nMAssay Description:Inhibition of recombinant HDAC7 (unknown origin) using Ac-peptide-AMC as substrate incubated for 240 mins by microplate reader analysisMore data for this Ligand-Target Pair
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