Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50195684![]() (1-[4-(3-fluoropropoxy)-3-methoxyphenyl]-5-hydroxy-...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.0700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sungkyunkwan University School of Medicine Curated by ChEMBL | Assay Description Displacement of [125I]IMSB from beta amyloid protein 40 | J Med Chem 49: 6111-9 (2006) Article DOI: 10.1021/jm0607193 BindingDB Entry DOI: 10.7270/Q2J38TB2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50101410![]() ((trans,trans)-1-bromo-2,5-bis-(3-hydroxycarbonyl-4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibitory activity against binding of [125I]-IMSB to amyloid beta in brain | J Med Chem 44: 2270-5 (2001) Article DOI: 10.1021/jm010161t BindingDB Entry DOI: 10.7270/Q22J6B4Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50101411![]() (5-[2-bromo-4-(3-carboxy-4-hydroxyphenethyl)pheneth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibitory activity against binding of [125I]-IMSB to amyloid beta in brain | J Med Chem 44: 2270-5 (2001) Article DOI: 10.1021/jm010161t BindingDB Entry DOI: 10.7270/Q22J6B4Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50100131![]() (5-(Biphenyl-4-ylazo)-bis (2-hydroxy-benzoic acid)(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant for aggregates of amyloid beta compared to [125I]-IMSB | J Med Chem 44: 1905-14 (2001) Article DOI: 10.1021/jm010045q BindingDB Entry DOI: 10.7270/Q2V69HV8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50100131![]() (5-(Biphenyl-4-ylazo)-bis (2-hydroxy-benzoic acid)(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibitory activity against binding of [125I]-IMSB to amyloid beta in brain | J Med Chem 44: 2270-5 (2001) Article DOI: 10.1021/jm010161t BindingDB Entry DOI: 10.7270/Q22J6B4Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50100131![]() (5-(Biphenyl-4-ylazo)-bis (2-hydroxy-benzoic acid)(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sungkyunkwan University School of Medicine Curated by ChEMBL | Assay Description Displacement of [125I]IMSB from beta amyloid protein 40 | J Med Chem 49: 6111-9 (2006) Article DOI: 10.1021/jm0607193 BindingDB Entry DOI: 10.7270/Q2J38TB2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50100135![]() ((E,E)-1-iodo-2,5-bis-(3-hydroxycarbonyl-4-methoxy)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant for aggregates of amyloid beta compared to [125I]-IMSB | J Med Chem 44: 1905-14 (2001) Article DOI: 10.1021/jm010045q BindingDB Entry DOI: 10.7270/Q2V69HV8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50101413![]() (5-[2-bromo-4-(3-carboxy-4-hydroxyphenethyl)pheneth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibitory activity against binding of [125I]-IMSB to amyloid beta in brain | J Med Chem 44: 2270-5 (2001) Article DOI: 10.1021/jm010161t BindingDB Entry DOI: 10.7270/Q22J6B4Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50067040![]() (((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.208 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Sungkyunkwan University School of Medicine Curated by ChEMBL | Assay Description Displacement of [125I]IMSB from beta amyloid protein 40 | J Med Chem 49: 6111-9 (2006) Article DOI: 10.1021/jm0607193 BindingDB Entry DOI: 10.7270/Q2J38TB2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50101412![]() (5-[2-bromo-4-(3-carboxy-4-hydroxyphenethyl)pheneth...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.270 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibitory activity against binding of [125I]-IMSB to amyloid beta in brain | J Med Chem 44: 2270-5 (2001) Article DOI: 10.1021/jm010161t BindingDB Entry DOI: 10.7270/Q22J6B4Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50100131![]() (5-(Biphenyl-4-ylazo)-bis (2-hydroxy-benzoic acid)(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.400 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant of compound on ligand binding to aggregates of Amyloid beta was measured by comparing with [125I]-IMSB | J Med Chem 44: 1905-14 (2001) Article DOI: 10.1021/jm010045q BindingDB Entry DOI: 10.7270/Q2V69HV8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50185948![]() (5-hydroxy-2-(4-methylaminophenyl)benzofuran | CHEM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nagasaki University Curated by ChEMBL | Assay Description Displacement of [125I]IMPY from beta amyloid in human corpse AD brain | J Med Chem 49: 2725-30 (2006) Article DOI: 10.1021/jm051176k BindingDB Entry DOI: 10.7270/Q23B5ZRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50100133![]() (CHEMBL55401 | [4-(6-Bromo-benzothiazol-2-yl)-pheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant for amyloid beta compared to [125I]-TZDM | J Med Chem 44: 1905-14 (2001) Article DOI: 10.1021/jm010045q BindingDB Entry DOI: 10.7270/Q2V69HV8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50100135![]() ((E,E)-1-iodo-2,5-bis-(3-hydroxycarbonyl-4-methoxy)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant for aggregates of amyloid beta compared to [125I]-IMSB | J Med Chem 44: 1905-14 (2001) Article DOI: 10.1021/jm010045q BindingDB Entry DOI: 10.7270/Q2V69HV8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50100130![]() (4-(6-Iodobenzo[d]thiazol-2-yl)-N,N-dimethylaniline...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant against [125I]-7 (TZDM) binding to Amyloid beta 1-40 aggregates | J Med Chem 46: 237-43 (2003) Article DOI: 10.1021/jm020351j BindingDB Entry DOI: 10.7270/Q2WH2PBC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50100130![]() (4-(6-Iodobenzo[d]thiazol-2-yl)-N,N-dimethylaniline...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.900 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant for amyloid beta compared to [125I]-TZDM | J Med Chem 44: 1905-14 (2001) Article DOI: 10.1021/jm010045q BindingDB Entry DOI: 10.7270/Q2V69HV8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50173640![]() (4-[(E)-2-(4-Dimethylamino-phenyl)-vinyl]-phenol | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant for I-125-IMPY binding to amyloid plaques in Alzheimers disease brain homogenates | J Med Chem 48: 5980-8 (2005) Article DOI: 10.1021/jm050166g BindingDB Entry DOI: 10.7270/Q2TB17PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50173647![]() ((E)-4-(4-(methylamino)styryl)phenol | 4-(4-(methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant for I-125-IMPY binding to amyloid plaques in Alzheimers disease brain homogenates | J Med Chem 48: 5980-8 (2005) Article DOI: 10.1021/jm050166g BindingDB Entry DOI: 10.7270/Q2TB17PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50173647![]() ((E)-4-(4-(methylamino)styryl)phenol | 4-(4-(methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Displacement of [125I]2-(4'-dimethylaminophenyl)-6-iodoimidazo[1,2-a]pyridine from beta amyloid peptide in brain tissue at 50 uL | J Med Chem 49: 2841-4 (2006) Article DOI: 10.1021/jm051020k BindingDB Entry DOI: 10.7270/Q2Q23ZT9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50185947![]() (5-methoxy-2-(4-methylaminophenyl)benzofuran | CHEM...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nagasaki University Curated by ChEMBL | Assay Description Displacement of [125I]IMPY from beta amyloid in human corpse AD brain | J Med Chem 49: 2725-30 (2006) Article DOI: 10.1021/jm051176k BindingDB Entry DOI: 10.7270/Q23B5ZRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50100132![]() (6-Bromo-2-[4-(4-methyl-piperazin-1-yl)-phenyl]-ben...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant for amyloid beta compared to [125I]-TZDM | J Med Chem 44: 1905-14 (2001) Article DOI: 10.1021/jm010045q BindingDB Entry DOI: 10.7270/Q2V69HV8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50129794![]() (CHEMBL328660 | [4-(6-Bromo-benzothiazol-2-yl)-phen...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1. | J Med Chem 46: 2740-54 (2003) Article DOI: 10.1021/jm030026b BindingDB Entry DOI: 10.7270/Q23R0S87 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50100133![]() (CHEMBL55401 | [4-(6-Bromo-benzothiazol-2-yl)-pheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant for amyloid beta compared to [125I]-TZDM | J Med Chem 44: 1905-14 (2001) Article DOI: 10.1021/jm010045q BindingDB Entry DOI: 10.7270/Q2V69HV8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50129784![]() (4-(6-Methoxybenzo[d]thiazol-2-yl)-N,N-dimethylanil...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1. | J Med Chem 46: 2740-54 (2003) Article DOI: 10.1021/jm030026b BindingDB Entry DOI: 10.7270/Q23R0S87 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50100130![]() (4-(6-Iodobenzo[d]thiazol-2-yl)-N,N-dimethylaniline...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant for amyloid beta compared to [125I]-TZDM | J Med Chem 44: 1905-14 (2001) Article DOI: 10.1021/jm010045q BindingDB Entry DOI: 10.7270/Q2V69HV8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50185946![]() (5-methoxy-2-(4-aminophenyl)benzofuran | CHEMBL2052...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nagasaki University Curated by ChEMBL | Assay Description Displacement of [125I]IMPY from beta amyloid in human corpse AD brain | J Med Chem 49: 2725-30 (2006) Article DOI: 10.1021/jm051176k BindingDB Entry DOI: 10.7270/Q23B5ZRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50129793![]() (2-(4''-methylaminophenyl)-6-hydroxybenzothiazole |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant for I-125-IMPY binding to amyloid plaques in Alzheimers disease brain homogenates | J Med Chem 48: 5980-8 (2005) Article DOI: 10.1021/jm050166g BindingDB Entry DOI: 10.7270/Q2TB17PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50129793![]() (2-(4''-methylaminophenyl)-6-hydroxybenzothiazole |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Displacement of [125I]2-(4'-dimethylaminophenyl)-6-iodoimidazo[1,2-a]pyridine from beta amyloid peptide in brain tissue at 50 uL | J Med Chem 49: 2841-4 (2006) Article DOI: 10.1021/jm051020k BindingDB Entry DOI: 10.7270/Q2Q23ZT9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50185950![]() (5-hydroxy-2-(4-dimethylaminophenyl)benzofuran | CH...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nagasaki University Curated by ChEMBL | Assay Description Displacement of [125I]IMPY from beta amyloid in human corpse AD brain | J Med Chem 49: 2725-30 (2006) Article DOI: 10.1021/jm051176k BindingDB Entry DOI: 10.7270/Q23B5ZRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50100133![]() (CHEMBL55401 | [4-(6-Bromo-benzothiazol-2-yl)-pheny...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1. | J Med Chem 46: 2740-54 (2003) Article DOI: 10.1021/jm030026b BindingDB Entry DOI: 10.7270/Q23R0S87 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50178546![]() (4-(5-(4-(2-fluoroethylamino)phenyl)thiophen-2-yl)p...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Displacement of [125I]IMPY from beta amyloid plaque in brain homogenates | Bioorg Med Chem Lett 16: 1350-2 (2006) Article DOI: 10.1016/j.bmcl.2005.11.055 BindingDB Entry DOI: 10.7270/Q2HX1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50129791![]() ((4-Benzothiazol-2-yl-phenyl)-dimethyl-amine | 4-(B...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1. | J Med Chem 46: 2740-54 (2003) Article DOI: 10.1021/jm030026b BindingDB Entry DOI: 10.7270/Q23R0S87 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM25849![]() (4-[5-(4-hydroxyphenyl)thiophen-2-yl]phenol | CHEMB...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Displacement of [125I]IMPY from beta amyloid plaque in brain homogenates | Bioorg Med Chem Lett 16: 1350-2 (2006) Article DOI: 10.1016/j.bmcl.2005.11.055 BindingDB Entry DOI: 10.7270/Q2HX1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50129793![]() (2-(4''-methylaminophenyl)-6-hydroxybenzothiazole |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1. | J Med Chem 46: 2740-54 (2003) Article DOI: 10.1021/jm030026b BindingDB Entry DOI: 10.7270/Q23R0S87 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50129793![]() (2-(4''-methylaminophenyl)-6-hydroxybenzothiazole |...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nagasaki University Curated by ChEMBL | Assay Description Binding affinity to beta amyloid in human corpse AD brain | J Med Chem 49: 2725-30 (2006) Article DOI: 10.1021/jm051176k BindingDB Entry DOI: 10.7270/Q23B5ZRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50129792![]() (2-(4-Dimethylamino-phenyl)-benzothiazol-6-ol | CHE...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1. | J Med Chem 46: 2740-54 (2003) Article DOI: 10.1021/jm030026b BindingDB Entry DOI: 10.7270/Q23R0S87 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50129786![]() (CHEMBL94230 | [4-(6-Methoxy-benzothiazol-2-yl)-phe...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1. | J Med Chem 46: 2740-54 (2003) Article DOI: 10.1021/jm030026b BindingDB Entry DOI: 10.7270/Q23R0S87 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50100132![]() (6-Bromo-2-[4-(4-methyl-piperazin-1-yl)-phenyl]-ben...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant for amyloid beta compared to [125I]-TZDM | J Med Chem 44: 1905-14 (2001) Article DOI: 10.1021/jm010045q BindingDB Entry DOI: 10.7270/Q2V69HV8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50122787![]() (2-(4'-dimethylaminophenyl)-6-iodoimidazo[1,2-a]pyr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Displacement of [125I]2-(4'-dimethylaminophenyl)-6-iodoimidazo[1,2-a]pyridine from beta amyloid peptide in brain tissue at 50 uL | J Med Chem 49: 2841-4 (2006) Article DOI: 10.1021/jm051020k BindingDB Entry DOI: 10.7270/Q2Q23ZT9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50422738![]() (CHEMBL567747) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant for I-125-IMPY binding to amyloid plaques in Alzheimers disease brain homogenates | J Med Chem 48: 5980-8 (2005) Article DOI: 10.1021/jm050166g BindingDB Entry DOI: 10.7270/Q2TB17PR | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50100135![]() ((E,E)-1-iodo-2,5-bis-(3-hydroxycarbonyl-4-methoxy)...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Displacement of [125I](E,E)-1-iodo-2,5-bis-(3-hydroxycarbonyl-4-methoxy)styrylbenzene from beta amyloid peptide in brain tissue at 50 uL | J Med Chem 49: 2841-4 (2006) Article DOI: 10.1021/jm051020k BindingDB Entry DOI: 10.7270/Q2Q23ZT9 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50100136![]() (6-Iodo-2-[4-(4-methyl-piperazin-1-yl)-phenyl]-benz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant for amyloid beta compared to [125I]-TZDM | J Med Chem 44: 1905-14 (2001) Article DOI: 10.1021/jm010045q BindingDB Entry DOI: 10.7270/Q2V69HV8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50178542![]() (4-(5-(4-methoxyphenyl)thiophen-2-yl)benzenamine | ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Displacement of [125I]IMPY from beta amyloid plaque in brain homogenates | Bioorg Med Chem Lett 16: 1350-2 (2006) Article DOI: 10.1016/j.bmcl.2005.11.055 BindingDB Entry DOI: 10.7270/Q2HX1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50334369![]() (3-(4-(Dimethylamino)phenyl)-1-(4-iodophenyl)-2-pro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kyoto University Curated by ChEMBL | Assay Description Displacement of [125I]DMIC from Amyloid beta (1 to 42) after 3 hrs by gamma counting | Bioorg Med Chem Lett 21: 117-20 (2010) Article DOI: 10.1016/j.bmcl.2010.11.058 BindingDB Entry DOI: 10.7270/Q2N87B2Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50173647![]() ((E)-4-(4-(methylamino)styryl)phenol | 4-(4-(methyl...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Nagasaki University Curated by ChEMBL | Assay Description Binding affinity to beta amyloid in human corpse AD brain | J Med Chem 49: 2725-30 (2006) Article DOI: 10.1021/jm051176k BindingDB Entry DOI: 10.7270/Q23B5ZRB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50178536![]() (4-(5-(4-methoxyphenyl)thiophen-2-yl)phenol | CHEMB...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Displacement of [125I]IMPY from beta amyloid plaque in brain homogenates | Bioorg Med Chem Lett 16: 1350-2 (2006) Article DOI: 10.1016/j.bmcl.2005.11.055 BindingDB Entry DOI: 10.7270/Q2HX1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50178547![]() (4-(5-(4-aminophenyl)thiophen-2-yl)benzenamine | CH...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Displacement of [125I]IMPY from beta amyloid plaque in brain homogenates | Bioorg Med Chem Lett 16: 1350-2 (2006) Article DOI: 10.1016/j.bmcl.2005.11.055 BindingDB Entry DOI: 10.7270/Q2HX1C83 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50100136![]() (6-Iodo-2-[4-(4-methyl-piperazin-1-yl)-phenyl]-benz...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 6.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pennsylvania Curated by ChEMBL | Assay Description Inhibition constant for amyloid beta compared to [125I]-TZDM | J Med Chem 44: 1905-14 (2001) Article DOI: 10.1021/jm010045q BindingDB Entry DOI: 10.7270/Q2V69HV8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50052701![]() (2-(4-Aminophenyl)-6-methoxybenzothiazole | 4-(6-Me...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1. | J Med Chem 46: 2740-54 (2003) Article DOI: 10.1021/jm030026b BindingDB Entry DOI: 10.7270/Q23R0S87 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Beta amyloid A4 protein (Homo sapiens (human)) | BDBM50129783![]() (4-(6-Bromo-benzothiazol-2-yl)-phenylamine | CHEMBL...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Pittsburgh Curated by ChEMBL | Assay Description Binding affinity for Amyloid beta 1-40 aggregates in competition with [N-methyl-3H] BTA-1. | J Med Chem 46: 2740-54 (2003) Article DOI: 10.1021/jm030026b BindingDB Entry DOI: 10.7270/Q23R0S87 | |||||||||||
More data for this Ligand-Target Pair |
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