Compile Data Set for Download or QSAR
maximum 50k data
Found 116 of ec50 for UniProtKB: P05067
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM4078(6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0...)
Affinity DataEC50:  1.70nMAssay Description:Inhibition of amyloid beta 1 to 42 aggregation (unknown origin) incubated for 24 hrs by inverted fluorescence microscopic analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50085536(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)
Affinity DataEC50:  1.70nMAssay Description:Inhibition of amyloid beta 1 to 42 aggregation (unknown origin) incubated for 24 hrs by ThT fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50595332(CHEMBL5179584)
Affinity DataEC50:  1.90nMAssay Description:Inhibition of amyloid beta 1 to 42 aggregation (unknown origin) incubated for 24 hrs by inverted fluorescence microscopic analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50242279(6,7,8,11,12,13,22,23-octahydroxy-3,16-dioxo-21-(3,...)
Affinity DataEC50:  3.20nMAssay Description:Inhibition of amyloid beta 1 to 42 aggregation (unknown origin) incubated for 24 hrs by inverted fluorescence microscopic analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50085536(3,4,5-Trihydroxybenzoate, X | 3,4,5-trihydroxybenz...)
Affinity DataEC50:  3.20nMAssay Description:Inhibition of amyloid beta 1 to 42 aggregation (unknown origin) incubated for 24 hrs by inverted fluorescence microscopic analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM4078(6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.0...)
Affinity DataEC50:  6nMAssay Description:Inhibition of amyloid beta 1 to 42 aggregation (unknown origin) incubated for 24 hrs by ThT fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455363(7-(2,3-Difluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S...)
Affinity DataEC50:  6nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50595332(CHEMBL5179584)
Affinity DataEC50:  6.70nMAssay Description:Inhibition of amyloid beta 1 to 42 aggregation (unknown origin) incubated for 24 hrs by ThT fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50242278(CHEMBL506069 | Geraniin | geraniiin)
Affinity DataEC50:  6.70nMAssay Description:Inhibition of amyloid beta 1 to 42 aggregation (unknown origin) incubated for 24 hrs by inverted fluorescence microscopic analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50242279(6,7,8,11,12,13,22,23-octahydroxy-3,16-dioxo-21-(3,...)
Affinity DataEC50:  8.90nMAssay Description:Inhibition of amyloid beta 1 to 42 aggregation (unknown origin) incubated for 24 hrs by ThT fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455353(7-(2,4-Difluorophenyl)-N2-((1R,5S,8s)-3-(6-methoxy...)
Affinity DataEC50:  9nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455358(7-(2,3-Difluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S...)
Affinity DataEC50:  9nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455355(2-((7-(4-Fluorophenyl)-2-(((1R,5S,8s)-3-(6-methoxy...)
Affinity DataEC50:  9nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455364(7-(2,3-Difluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S...)
Affinity DataEC50:  10nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50242278(CHEMBL506069 | Geraniin | geraniiin)
Affinity DataEC50:  10nMAssay Description:Inhibition of amyloid beta 1 to 42 aggregation (unknown origin) incubated for 24 hrs by ThT fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455341(N2-((1R,5S,8s)-3-(6-Chloropyridazin-4-yl)-3-azabic...)
Affinity DataEC50:  11nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455344(7-(4-Fluorophenyl)-N4-methyl-N2-((1R,5S,8s)-3-(6-m...)
Affinity DataEC50:  12nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455354(2-((7-(4-Fluorophenyl)-5,5-dimethyl-2-(((1R,5S,8s)...)
Affinity DataEC50:  12nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455336(7-(4-Fluorophenyl)-N2-((1R,5S,8s)-3-(6-methoxypyri...)
Affinity DataEC50:  12nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455349(7-(2,4-Difluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S...)
Affinity DataEC50:  14nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455334(7-(4-Fluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S,8s)...)
Affinity DataEC50:  14nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455359((S)- or (R)-7-(4-Fluorophenyl)-N4,5-dimethyl-N2-((...)
Affinity DataEC50:  16nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455345(7-(3,4-Difluorophenyl)-N2-((1R,5S,8s)-3-(6-methoxy...)
Affinity DataEC50:  16nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455360((R)- or (S)-7-(4-Fluorophenyl)-N4,5-dimethyl-N2-((...)
Affinity DataEC50:  17nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455346(7-(4-Fluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S,8s)...)
Affinity DataEC50:  19nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455337(7-(4-Fluorophenyl)-N2-((1R,5S,8s)-3-(2-methoxypyri...)
Affinity DataEC50:  23nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455343(7-(3,4-Difluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S...)
Affinity DataEC50:  24nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455357(8-(4-Fluorophenyl)-N2-((1R,5S,8s)-3-(6-methoxypyri...)
Affinity DataEC50:  24nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455338(N2-((1R,5S,8s)-3-(6-Chloropyrimidin-4-yl)-3-azabic...)
Affinity DataEC50:  31nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455350(7-(2,4-Difluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S...)
Affinity DataEC50:  31nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455342(7-(3,4-Difluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S...)
Affinity DataEC50:  33nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455335(7-(4-Fluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S,8s)...)
Affinity DataEC50:  34nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455356(8-(4-Fluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S,8s)...)
Affinity DataEC50:  35nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50236004(CHEMBL4101809)
Affinity DataEC50:  35nMAssay Description:Modulation of amyloid beta 42 in human H4 cells expressing APP751 incubated overnight by ELISAMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455347(7-(3,3-Difluorocyclobutyl)-N4,5,5-trimethyl-N2-((1...)
Affinity DataEC50:  36nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455339(7-(4-Fluorophenyl)-N2-((1R,5S,8s)-3-(6-methoxypyri...)
Affinity DataEC50:  46nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455352(N2-((1R,5S,8s)-3-(6-Methoxypyridazin-4-yl)-3-azabi...)
Affinity DataEC50:  53nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM28960((2R)-2-{[5-chloro-2-(hydroxymethyl)phenyl](4-chlor...)
Affinity DataEC50:  100nMAssay Description:In vitro effective concentration against beta amyloid protein 40 in ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455348(7-(3,3-Difluorocyclobutyl)-N4,5,5-trimethyl-N2-((1...)
Affinity DataEC50:  104nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM455351(N4,5,5-Trimethyl-N2-((1R,5S,8s)-3-(6-methylpyrimid...)
Affinity DataEC50:  111nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50305469(CHEMBL590830 | N-(3-(2-amino-4-cyclohexyl-1-methyl...)
Affinity DataEC50:  180nMAssay Description:Inhibition of human recombinant APP expressed in CHO-K1 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50314993(2-(2-amino-6-((2-(2-chlorophenyl)-5-(4-(pyrimidin-...)
Affinity DataEC50:  190nMAssay Description:Inhibition of human recombinant APP in CHO cells assessed as decrease in beta amyloid protein level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50314994(2-(2-amino-6-((2-(2-chlorophenyl)-5-(4-(pyrimidin-...)
Affinity DataEC50:  440nMAssay Description:Inhibition of human recombinant APP in CHO cells assessed as decrease in beta amyloid protein level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50163996(4-(4-Chloro-benzenesulfonyl)-4-(2-methoxy-phenyl)-...)
Affinity DataEC50:  530nMAssay Description:In vitro reduction of Swedish NL mutant amyloid precursor protein activity expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50163996(4-(4-Chloro-benzenesulfonyl)-4-(2-methoxy-phenyl)-...)
Affinity DataEC50:  640nMAssay Description:In vitro elevation of beta C-terminal fragment (Ct-99) in CHO cells expressing mutant Swedish NL human APPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50305467(2-amino-4-cyclohexyl-1-methyl-4-phenyl-1H-imidazol...)
Affinity DataEC50:  810nMAssay Description:Inhibition of human recombinant APP expressed in CHO-K1 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50163996(4-(4-Chloro-benzenesulfonyl)-4-(2-methoxy-phenyl)-...)
Affinity DataEC50:  1.03E+3nMAssay Description:In vitro inhibition of amyloid precursor protein 695 activity in CHO cells expressing human APPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50305483(2-amino-4,4-dicyclohexyl-1-methyl-1H-imidazol-5(4H...)
Affinity DataEC50:  1.03E+3nMAssay Description:Inhibition of human recombinant APP expressed in CHO-K1 cells assessed as reduction of amyloid beta level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50315005(6-((2-(2-chlorophenyl)-5-(4-(pentyloxy)phenyl)-1H-...)
Affinity DataEC50:  2.10E+3nMAssay Description:Inhibition of human recombinant APP in CHO cells assessed as decrease in beta amyloid protein level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Muroran Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50315000(6-((2-(2-chlorophenyl)-5-(4-(pyrimidin-5-yloxy)phe...)
Affinity DataEC50:  2.20E+3nMAssay Description:Inhibition of human recombinant APP in CHO cells assessed as decrease in beta amyloid protein level by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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