Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50403647![]() (CHEMBL27013) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.145 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50060964![]() ((R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-...) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 0.204 | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro antagonism against Alpha-1B adrenergic receptor using phenylephrine (PE) challenge in rat spleen | J Med Chem 40: 3141-3 (1997) Article DOI: 10.1021/jm970364a BindingDB Entry DOI: 10.7270/Q2R78DBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50392641![]() (CHEMBL2153553) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.263 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Milano Curated by ChEMBL | Assay Description Antagonist activity at alpha1B adrenoceptor in Sprague-Dawley rat spleen assessed as inhibition of phenylephrine-induced contractions after 30 mins | Eur J Med Chem 58: 184-91 (2012) Article DOI: 10.1016/j.ejmech.2012.09.049 BindingDB Entry DOI: 10.7270/Q2WQ04W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM86731![]() (CAS_74191-85-8 | DOXAZOSIN | Doxazosin | UK 33,274) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase DrugBank KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.309 | n/a | n/a | n/a | n/a | n/a |
University of Camerino Curated by ChEMBL | Assay Description Antagonist activity at rat Alpha-1B adrenoceptor assessed as inhibition if phenylephrine-induced contraction of spleen | J Med Chem 52: 4951-4 (2009) Article DOI: 10.1021/jm8016046 BindingDB Entry DOI: 10.7270/Q2NZ88W5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50408671![]() (CHEMBL144224) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.447 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50408676![]() (CHEMBL138681) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.617 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50403649![]() (CYCLAZOSIN) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.661 | n/a | n/a | n/a | n/a | n/a |
University of Camerino Curated by ChEMBL | Assay Description Antagonist activity at rat Alpha-1B adrenoceptor assessed as inhibition if phenylephrine-induced contraction of spleen | J Med Chem 52: 4951-4 (2009) Article DOI: 10.1021/jm8016046 BindingDB Entry DOI: 10.7270/Q2NZ88W5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50392637![]() (CHEMBL215421) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.676 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Milano Curated by ChEMBL | Assay Description Antagonist activity at alpha1B adrenoceptor in Sprague-Dawley rat spleen assessed as inhibition of phenylephrine-induced contractions after 30 mins | Eur J Med Chem 58: 184-91 (2012) Article DOI: 10.1016/j.ejmech.2012.09.049 BindingDB Entry DOI: 10.7270/Q2WQ04W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50408677![]() (CHEMBL144776) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.676 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50408674![]() (CHEMBL358060) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 0.708 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM29568![]() (CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 0.977 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Blocking activity was assessed by antagonism of (-)-phenylephrine induced contraction of rat spleen (alpha1B adrenoceptor) | J Med Chem 48: 28-31 (2005) Article DOI: 10.1021/jm049153d BindingDB Entry DOI: 10.7270/Q20866HV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50410226![]() (CHEMBL178673) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.02 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Blocking activity was assessed by antagonism of (-)-phenylephrine induced contraction of rat spleen (alpha1B adrenoceptor) | J Med Chem 48: 28-31 (2005) Article DOI: 10.1021/jm049153d BindingDB Entry DOI: 10.7270/Q20866HV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM29568![]() (CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.02 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50408675![]() (CHEMBL144238) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.07 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50417540![]() (CHEMBL1630940) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Camerino Curated by ChEMBL | Assay Description Antagonist activity at Alpha-1B adrenoceptor in Wistar rat spleen assessed as phenylephrine induced contractions after 30 mins | Eur J Med Chem 45: 5800-7 (2010) Article DOI: 10.1016/j.ejmech.2010.09.042 BindingDB Entry DOI: 10.7270/Q2TX3GNT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50410227![]() (CHEMBL175934) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.74 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Blocking activity was assessed by antagonism of (-)-phenylephrine induced contraction of rat spleen (alpha1B adrenoceptor) | J Med Chem 48: 28-31 (2005) Article DOI: 10.1021/jm049153d BindingDB Entry DOI: 10.7270/Q20866HV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50408680![]() (CHEMBL144677) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 1.86 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50411351![]() (CHEMBL242507) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.24 | n/a | n/a | n/a | n/a | n/a |
University of Camerino Curated by ChEMBL | Assay Description Antagonist activity against adrenergic Alpha-1B receptor in rat spleen assessed as inhibition of phenylephrine-induced response | Bioorg Med Chem 15: 2334-45 (2007) Article DOI: 10.1016/j.bmc.2007.01.028 BindingDB Entry DOI: 10.7270/Q2G16229 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50408679![]() (CHEMBL342997) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.40 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50408668![]() (CHEMBL357669) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.45 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50033111![]() (1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-((tetra...) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 2.5 | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro antagonism against Alpha-1B adrenergic receptor using phenylephrine (PE) challenge in rat spleen | J Med Chem 40: 3141-3 (1997) Article DOI: 10.1021/jm970364a BindingDB Entry DOI: 10.7270/Q2R78DBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50392645![]() (CHEMBL2153557) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.75 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Milano Curated by ChEMBL | Assay Description Antagonist activity at alpha1B adrenoceptor in Sprague-Dawley rat spleen assessed as inhibition of phenylephrine-induced contractions after 30 mins | Eur J Med Chem 58: 184-91 (2012) Article DOI: 10.1016/j.ejmech.2012.09.049 BindingDB Entry DOI: 10.7270/Q2WQ04W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50408678![]() (CHEMBL144263) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 2.95 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50158584![]() (2-[4-(4-Amino-6,7-dimethoxy-quinazolin-2-yl)-piper...) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 3.09 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Blocking activity was assessed by antagonism of (-)-phenylephrine induced contraction of rat spleen (alpha1B adrenoceptor) | J Med Chem 48: 28-31 (2005) Article DOI: 10.1021/jm049153d BindingDB Entry DOI: 10.7270/Q20866HV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM69602![]() (2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dim...) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 6.17 | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL | Assay Description Antagonistic activity against (-)-phenylephrine-induced contraction of rat spleen (Alpha-1B adrenergic receptor ) | J Med Chem 46: 1504-11 (2003) Article DOI: 10.1021/jm021078o BindingDB Entry DOI: 10.7270/Q2VQ33WN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM69602![]() (2,3-dihydro-1,4-benzodioxin-3-ylmethyl-[2-(2,6-dim...) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 6.92 | n/a | n/a | n/a | n/a | n/a |
University of Camerino Curated by ChEMBL | Assay Description Antagonistic affinity tested against isolated Rat Spleen Alpha-1B adrenergic receptor | J Med Chem 45: 1633-43 (2002) Article DOI: 10.1021/jm011066n BindingDB Entry DOI: 10.7270/Q2542PSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50392643![]() (CHEMBL2153555) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 8.91 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Milano Curated by ChEMBL | Assay Description Antagonist activity at alpha1B adrenoceptor in Sprague-Dawley rat spleen assessed as inhibition of phenylephrine-induced contractions after 30 mins | Eur J Med Chem 58: 184-91 (2012) Article DOI: 10.1016/j.ejmech.2012.09.049 BindingDB Entry DOI: 10.7270/Q2WQ04W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50408682![]() (CHEMBL148061) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 9.33 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50408670![]() (CHEMBL144768) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 9.77 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50060965![]() (2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-...) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories Curated by ChEMBL | Assay Description In vitro antagonism against Alpha-1B adrenergic receptor using phenylephrine (PE) challenge in rat spleen | J Med Chem 40: 3141-3 (1997) Article DOI: 10.1021/jm970364a BindingDB Entry DOI: 10.7270/Q2R78DBB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50408669![]() (CHEMBL146724) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 13.2 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50392639![]() (CHEMBL2153551) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 15.8 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Milano Curated by ChEMBL | Assay Description Antagonist activity at alpha1B adrenoceptor in Sprague-Dawley rat spleen assessed as inhibition of phenylephrine-induced contractions after 30 mins | Eur J Med Chem 58: 184-91 (2012) Article DOI: 10.1016/j.ejmech.2012.09.049 BindingDB Entry DOI: 10.7270/Q2WQ04W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50392647![]() (CHEMBL2153559) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 16.6 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Milano Curated by ChEMBL | Assay Description Antagonist activity at alpha1B adrenoceptor in Sprague-Dawley rat spleen assessed as inhibition of phenylephrine-induced contractions after 30 mins | Eur J Med Chem 58: 184-91 (2012) Article DOI: 10.1016/j.ejmech.2012.09.049 BindingDB Entry DOI: 10.7270/Q2WQ04W7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50408672![]() (CHEMBL144000) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 19.5 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50409687![]() (CHEMBL44403) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 26.3 | n/a | n/a | n/a | n/a | n/a |
University of Camerino Curated by ChEMBL | Assay Description Antagonistic affinity tested against isolated Rat Spleen Alpha-1B adrenergic receptor | J Med Chem 45: 1633-43 (2002) Article DOI: 10.1021/jm011066n BindingDB Entry DOI: 10.7270/Q2542PSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50026917![]() (8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-a...) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 28.2 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50409690![]() (CHEMBL42472) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 28.8 | n/a | n/a | n/a | n/a | n/a |
University of Camerino Curated by ChEMBL | Assay Description Antagonistic affinity tested against isolated Rat Spleen Alpha-1B adrenergic receptor | J Med Chem 45: 1633-43 (2002) Article DOI: 10.1021/jm011066n BindingDB Entry DOI: 10.7270/Q2542PSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50417539![]() (CHEMBL1630941) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 30.9 | n/a | n/a | n/a | n/a | n/a |
Universit£ di Camerino Curated by ChEMBL | Assay Description Antagonist activity at Alpha-1B adrenoceptor in Wistar rat spleen assessed as phenylephrine induced contractions after 30 mins | Eur J Med Chem 45: 5800-7 (2010) Article DOI: 10.1016/j.ejmech.2010.09.042 BindingDB Entry DOI: 10.7270/Q2TX3GNT | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50403651![]() (CHEMBL29591) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 32.4 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50026917![]() (8-(2-(4-(2-methoxyphenyl)piperazin-1-yl)ethyl)-8-a...) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 33.1 | n/a | n/a | n/a | n/a | n/a |
University of Camerino Curated by ChEMBL | Assay Description Antagonistic affinity tested against isolated Rat Spleen Alpha-1B adrenergic receptor | J Med Chem 45: 1633-43 (2002) Article DOI: 10.1021/jm011066n BindingDB Entry DOI: 10.7270/Q2542PSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50408683![]() (CHEMBL341665) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 37.1 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50410225![]() (CHEMBL178923) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 40.7 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Blocking activity was assessed by antagonism of (-)-phenylephrine induced contraction of rat spleen (alpha1B adrenoceptor) | J Med Chem 48: 28-31 (2005) Article DOI: 10.1021/jm049153d BindingDB Entry DOI: 10.7270/Q20866HV | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50408673![]() (CHEMBL145181) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 42.7 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50409811![]() (CHEMBL1082862 | CHEMBL286003) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 43.6 | n/a | n/a | n/a | n/a | n/a |
Universit£ degli Studi di Modena e Reggio Emilia Curated by ChEMBL | Assay Description Antagonistic activity against (-)-phenylephrine-induced contraction of rat spleen (Alpha-1B adrenergic receptor ) | J Med Chem 46: 1504-11 (2003) Article DOI: 10.1021/jm021078o BindingDB Entry DOI: 10.7270/Q2VQ33WN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50408667![]() (CHEMBL146601) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 53.7 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50408681![]() (CHEMBL145384) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | 66.1 | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Antagonism of phenylephrine stimulated contraction of the rat isolated spleen. | J Med Chem 41: 4844-53 (1998) Article DOI: 10.1021/jm9810654 BindingDB Entry DOI: 10.7270/Q22J6D3B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50409691![]() (CHEMBL42558) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 67.6 | n/a | n/a | n/a | n/a | n/a |
University of Camerino Curated by ChEMBL | Assay Description Antagonistic affinity tested against isolated Rat Spleen Alpha-1B adrenergic receptor | J Med Chem 45: 1633-43 (2002) Article DOI: 10.1021/jm011066n BindingDB Entry DOI: 10.7270/Q2542PSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50409688![]() (CHEMBL42231) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a |
University of Camerino Curated by ChEMBL | Assay Description Antagonistic affinity tested against isolated Rat Spleen Alpha-1B adrenergic receptor | J Med Chem 45: 1633-43 (2002) Article DOI: 10.1021/jm011066n BindingDB Entry DOI: 10.7270/Q2542PSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50409692![]() (CHEMBL40325) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 155 | n/a | n/a | n/a | n/a | n/a |
University of Camerino Curated by ChEMBL | Assay Description Antagonistic affinity tested against isolated Rat Spleen Alpha-1B adrenergic receptor | J Med Chem 45: 1633-43 (2002) Article DOI: 10.1021/jm011066n BindingDB Entry DOI: 10.7270/Q2542PSW | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha adrenergic receptor 1A and 1B (Rattus norvegicus (rat)) | BDBM50409692![]() (CHEMBL40325) | Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 302 | n/a | n/a | n/a | n/a | n/a |
University of Camerino Curated by ChEMBL | Assay Description Antagonistic affinity tested against isolated Rat Spleen Alpha-1B adrenergic receptor | J Med Chem 45: 1633-43 (2002) Article DOI: 10.1021/jm011066n BindingDB Entry DOI: 10.7270/Q2542PSW | |||||||||||
More data for this Ligand-Target Pair |
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