Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM31183![]() (thiazol-2-amine, 14) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia at Charlottesville | Assay Description His6-CBFbeta (1-141) was expressed and purified with the exception of the protease cleavage step. Cerulean-Runt domain fusion protein (Runx1 41-190) ... | Chem Biol 14: 1186-97 (2007) Article DOI: 10.1016/j.chembiol.2007.09.006 BindingDB Entry DOI: 10.7270/Q2862DTN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29675![]() (2-methyl-N-(4-thiazolo[5,4-b]pyridin-2-ylphenyl)-1...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | n/a | n/a | 713 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q25D8Q6Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM31183![]() (thiazol-2-amine, 14) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Virginia at Charlottesville | Assay Description For the FRET measurements, the Cerulean-Runt (Runx1 41-190) and Venus-CBFbeta (1-141) fusion proteins were dialyzed into FRET assay buffer. Protein c... | Chem Biol 14: 1186-97 (2007) Article DOI: 10.1016/j.chembiol.2007.09.006 BindingDB Entry DOI: 10.7270/Q2862DTN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29652![]() (5-chloranyl-N-[4-([1,3]thiazolo[5,4-b]pyridin-2-yl...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | n/a | n/a | 1.87E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q25D8Q6Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM31175![]() (thiazol-2-amine, 5) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia at Charlottesville | Assay Description His6-CBFbeta (1-141) was expressed and purified with the exception of the protease cleavage step. Cerulean-Runt domain fusion protein (Runx1 41-190) ... | Chem Biol 14: 1186-97 (2007) Article DOI: 10.1016/j.chembiol.2007.09.006 BindingDB Entry DOI: 10.7270/Q2862DTN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM31186![]() (thiazol-2-amine, 18) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia at Charlottesville | Assay Description His6-CBFbeta (1-141) was expressed and purified with the exception of the protease cleavage step. Cerulean-Runt domain fusion protein (Runx1 41-190) ... | Chem Biol 14: 1186-97 (2007) Article DOI: 10.1016/j.chembiol.2007.09.006 BindingDB Entry DOI: 10.7270/Q2862DTN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM31185![]() (thiazol-2-amine, 17) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Virginia at Charlottesville | Assay Description For the FRET measurements, the Cerulean-Runt (Runx1 41-190) and Venus-CBFbeta (1-141) fusion proteins were dialyzed into FRET assay buffer. Protein c... | Chem Biol 14: 1186-97 (2007) Article DOI: 10.1016/j.chembiol.2007.09.006 BindingDB Entry DOI: 10.7270/Q2862DTN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM31182![]() (thiazol-2-amine, 13) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia at Charlottesville | Assay Description His6-CBFbeta (1-141) was expressed and purified with the exception of the protease cleavage step. Cerulean-Runt domain fusion protein (Runx1 41-190) ... | Chem Biol 14: 1186-97 (2007) Article DOI: 10.1016/j.chembiol.2007.09.006 BindingDB Entry DOI: 10.7270/Q2862DTN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM31185![]() (thiazol-2-amine, 17) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia at Charlottesville | Assay Description His6-CBFbeta (1-141) was expressed and purified with the exception of the protease cleavage step. Cerulean-Runt domain fusion protein (Runx1 41-190) ... | Chem Biol 14: 1186-97 (2007) Article DOI: 10.1016/j.chembiol.2007.09.006 BindingDB Entry DOI: 10.7270/Q2862DTN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29666![]() ((9-Oxo-9H-acridin-10-yl)-acetic acid [1-(4-chloro-...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 3.58E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q25D8Q6Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM30648![]() (MLS-0062362.0001 | N-(4-thiazolo[5,4-b]pyridin-2-y...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | n/a | n/a | 3.64E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q25D8Q6Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM31182![]() (thiazol-2-amine, 13) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.00E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Virginia at Charlottesville | Assay Description For the FRET measurements, the Cerulean-Runt (Runx1 41-190) and Venus-CBFbeta (1-141) fusion proteins were dialyzed into FRET assay buffer. Protein c... | Chem Biol 14: 1186-97 (2007) Article DOI: 10.1016/j.chembiol.2007.09.006 BindingDB Entry DOI: 10.7270/Q2862DTN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM31179![]() (thiazol-2-amine, 9) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia at Charlottesville | Assay Description His6-CBFbeta (1-141) was expressed and purified with the exception of the protease cleavage step. Cerulean-Runt domain fusion protein (Runx1 41-190) ... | Chem Biol 14: 1186-97 (2007) Article DOI: 10.1016/j.chembiol.2007.09.006 BindingDB Entry DOI: 10.7270/Q2862DTN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM31178![]() (thiazol-2-amine, 8) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia at Charlottesville | Assay Description His6-CBFbeta (1-141) was expressed and purified with the exception of the protease cleavage step. Cerulean-Runt domain fusion protein (Runx1 41-190) ... | Chem Biol 14: 1186-97 (2007) Article DOI: 10.1016/j.chembiol.2007.09.006 BindingDB Entry DOI: 10.7270/Q2862DTN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29658![]() (MLS000557330 | N-[3-Cyano-1-furan-2-ylmethyl-8-met...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 6.54E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29658![]() (MLS000557330 | N-[3-Cyano-1-furan-2-ylmethyl-8-met...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 6.54E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29639![]() ((4E)-3-methyl-4-[[3-[(2-methyl-4-oxidanyl-phenyl)a...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 7.08E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29639![]() ((4E)-3-methyl-4-[[3-[(2-methyl-4-oxidanyl-phenyl)a...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 7.08E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29643![]() ((6aS)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | n/a | n/a | 7.12E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29643![]() ((6aS)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | n/a | n/a | 7.12E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29672![]() (5-(2-keto-7-methoxy-4-propionyloxy-6-propyl-chrome...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | n/a | n/a | 7.94E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29672![]() (5-(2-keto-7-methoxy-4-propionyloxy-6-propyl-chrome...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | n/a | n/a | 7.94E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29643![]() ((6aS)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | n/a | n/a | 8.48E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q25D8Q6Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29632![]() (2-[2-(3-keto-1,2-benzothiazol-2-yl)thiazol-4-yl]ac...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | n/a | n/a | 8.58E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29632![]() (2-[2-(3-keto-1,2-benzothiazol-2-yl)thiazol-4-yl]ac...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | n/a | n/a | 8.58E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM31178![]() (thiazol-2-amine, 8) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Virginia at Charlottesville | Assay Description For the FRET measurements, the Cerulean-Runt (Runx1 41-190) and Venus-CBFbeta (1-141) fusion proteins were dialyzed into FRET assay buffer. Protein c... | Chem Biol 14: 1186-97 (2007) Article DOI: 10.1016/j.chembiol.2007.09.006 BindingDB Entry DOI: 10.7270/Q2862DTN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM31175![]() (thiazol-2-amine, 5) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Virginia at Charlottesville | Assay Description For the FRET measurements, the Cerulean-Runt (Runx1 41-190) and Venus-CBFbeta (1-141) fusion proteins were dialyzed into FRET assay buffer. Protein c... | Chem Biol 14: 1186-97 (2007) Article DOI: 10.1016/j.chembiol.2007.09.006 BindingDB Entry DOI: 10.7270/Q2862DTN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29644![]() ((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase DrugBank PC cid PC sid UniChem Similars | n/a | n/a | 9.81E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29644![]() ((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase DrugBank PC cid PC sid UniChem Similars | n/a | n/a | 9.81E+3 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29668![]() (2-(1-{[4-(2,5-Dimethyl-phenyl)-thiazol-2-yl]-hydra...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 1.01E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29668![]() (2-(1-{[4-(2,5-Dimethyl-phenyl)-thiazol-2-yl]-hydra...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 1.01E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM576![]() (1-Diphenylamino-pyrrole-2,5-dione | MLS000590474 |...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem | n/a | n/a | 1.03E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q25D8Q6Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29685![]() ((3E)-3-(2-furanylmethylidene)-1,2-dihydrocyclopent...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 1.04E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29685![]() ((3E)-3-(2-furanylmethylidene)-1,2-dihydrocyclopent...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 1.04E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29684![]() ((3E)-3-(2-furanylmethylidene)-1,2-dihydrocyclopent...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 1.06E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29684![]() ((3E)-3-(2-furanylmethylidene)-1,2-dihydrocyclopent...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 1.06E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29666![]() ((9-Oxo-9H-acridin-10-yl)-acetic acid [1-(4-chloro-...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 1.16E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29666![]() ((9-Oxo-9H-acridin-10-yl)-acetic acid [1-(4-chloro-...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 1.16E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29661![]() (2-Amino-1-furan-2-ylmethyl-1H-pyrrolo[2,3-b]quinox...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | n/a | n/a | 1.17E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29661![]() (2-Amino-1-furan-2-ylmethyl-1H-pyrrolo[2,3-b]quinox...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | n/a | n/a | 1.17E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM31179![]() (thiazol-2-amine, 9) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | 7.5 | 23 |
University of Virginia at Charlottesville | Assay Description For the FRET measurements, the Cerulean-Runt (Runx1 41-190) and Venus-CBFbeta (1-141) fusion proteins were dialyzed into FRET assay buffer. Protein c... | Chem Biol 14: 1186-97 (2007) Article DOI: 10.1016/j.chembiol.2007.09.006 BindingDB Entry DOI: 10.7270/Q2862DTN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM31176![]() (thiazol-2-amine, 6) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Virginia at Charlottesville | Assay Description His6-CBFbeta (1-141) was expressed and purified with the exception of the protease cleavage step. Cerulean-Runt domain fusion protein (Runx1 41-190) ... | Chem Biol 14: 1186-97 (2007) Article DOI: 10.1016/j.chembiol.2007.09.006 BindingDB Entry DOI: 10.7270/Q2862DTN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM30647![]() (MLS-0291694.0001 | N-(4-thiazolo[5,4-b]pyridin-2-y...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 1.28E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q25D8Q6Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29665![]() ((9-Oxo-9H-acridin-10-yl)-acetic acid (2,5-dimethyl...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29665![]() ((9-Oxo-9H-acridin-10-yl)-acetic acid (2,5-dimethyl...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29682![]() (2-(dichloromethyl)-7-(phenylmethyl)-3,5,6,8-tetrah...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | n/a | n/a | 1.34E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2T72FSX | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29682![]() (2-(dichloromethyl)-7-(phenylmethyl)-3,5,6,8-tetrah...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | n/a | n/a | 1.34E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29644![]() ((6aR)-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase DrugBank PC cid PC sid UniChem Similars | n/a | n/a | 1.34E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q25D8Q6Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29666![]() ((9-Oxo-9H-acridin-10-yl)-acetic acid [1-(4-chloro-...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | PC cid PC sid UniChem Similars | n/a | n/a | 1.36E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC. This is accomplished by usin... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2959FWK | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Runt-Related Transcription Factor 1 Isoform AML1C (Homo sapiens) | BDBM29688![]() (3-(9-(3-chloro-4-{[(4-methylphenyl)sulfonyl]oxy}ph...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet ![]() | Purchase PC cid PC sid UniChem Similars | n/a | n/a | 1.46E+4 | n/a | n/a | n/a | n/a | 7.4 | 23 | |
Burnham Center for Chemical Genomics Curated by PubChem BioAssay | Assay Description This assay is to use HTS to identify inhibitors of the protein-protein interaction between the RUNX1 Runt domain and CBFbeta-SMMHC, a potential thera... | PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2DV1H7P | |||||||||||
More data for this Ligand-Target Pair |
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