Affinity DataKi: 0.0140nMAssay Description:Antagonistic activity against estrogen receptor beta in presence of 0.1 nM estradiolMore data for this Ligand-Target Pair
Affinity DataKi: 0.0150nMpH: 7.5Assay Description:The method employed was adapted from the scientific literature and described in detail by Osbourn et al. (1993, Biochemistry, 32, 6229-6236). Recombi...More data for this Ligand-Target Pair
Affinity DataKi: 0.0150nM ΔG°: -14.8kcal/molepH: 7.5 T: 2°CAssay Description:The method employed was adapted from the scientific literature and described in detail by Osbourn et al. (1993, Biochemistry, 32, 6229-6236). Recombi...More data for this Ligand-Target Pair
Affinity DataKi: 0.0150nM ΔG°: -14.8kcal/molepH: 7.5 T: 2°CAssay Description:The method employed was adapted from the scientific literature and described in detail by Osboum et al. (1993, Biochemistry, 32, 6229-6236). Recombin...More data for this Ligand-Target Pair
Affinity DataKi: 0.0250nMpH: 7.5Assay Description:The method employed was adapted from the scientific literature and described in detail by Osbourn et al. (1993, Biochemistry, 32, 6229-6236). Recombi...More data for this Ligand-Target Pair
Affinity DataKi: 0.0250nM ΔG°: -14.5kcal/molepH: 7.5 T: 2°CAssay Description:The method employed was adapted from the scientific literature and described in detail by Osbourn et al. (1993, Biochemistry, 32, 6229-6236). Recombi...More data for this Ligand-Target Pair
Affinity DataKi: 0.0250nM ΔG°: -14.5kcal/molepH: 7.5 T: 2°CAssay Description:The method employed was adapted from the scientific literature and described in detail by Osboum et al. (1993, Biochemistry, 32, 6229-6236). Recombin...More data for this Ligand-Target Pair
Affinity DataKi: 0.0480nMAssay Description:Relative binding affinity for human estrogen receptor betacompared to [3H]-estradiolMore data for this Ligand-Target Pair
Affinity DataKi: 0.0600nMAssay Description:Displacement of [3H]-estradiol from Estrogen receptor betaMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:In vitro displacement of 0.5 nM [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
Affinity DataKi: 0.160nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
Affinity DataKi: 0.170nM ΔG°: -13.2kcal/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataKi: 0.190nM ΔG°: -13.1kcal/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataKi: 0.190nM ΔG°: -13.1kcal/mole EC50: 0.660nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataKi: 0.190nMAssay Description:Antagonistic activity against estrogen receptor beta in presence of 0.1 nM estradiolMore data for this Ligand-Target Pair
Affinity DataKi: 0.190nM ΔG°: -13.1kcal/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataKi: 0.260nM ΔG°: -12.9kcal/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataKi: 0.270nMAssay Description:Relative binding affinity for human estrogen receptor betacompared to [3H]-estradiolMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
Affinity DataKi: 0.280nM ΔG°: -12.9kcal/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataKi: 0.280nM ΔG°: -12.9kcal/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataKi: 0.290nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
Affinity DataKi: 0.300nM ΔG°: -12.9kcal/mole EC50: 3.18nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
TargetEstrogen receptor beta(Mus musculus)
University Of New Mexico Health Sciences Center
Curated by ChEMBL
University Of New Mexico Health Sciences Center
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Binding affinity to ERbeta receptor in mouse COS7 cells by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.310nM ΔG°: -12.8kcal/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataKi: 0.350nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
Affinity DataKi: 0.360nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Displacement of [3H]estradiol from human full-length ERbeta receptor by competitive radiometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.380nMAssay Description:Displacement of E2-Alexa633 from GFP-tagged ERbeta expressed in COS7 cells by FACSMore data for this Ligand-Target Pair
Affinity DataKi: 0.410nM ΔG°: -12.7kcal/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataKi: 0.430nMAssay Description:Displacement of [3H]-estradiol from Estrogen receptor betaMore data for this Ligand-Target Pair
Affinity DataKi: 0.440nM ΔG°: -12.6kcal/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataKi: 0.440nM ΔG°: -12.6kcal/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataKi: 0.460nMAssay Description:Antagonistic activity against estrogen receptor beta in presence of 0.1 nM estradiolMore data for this Ligand-Target Pair
Affinity DataKi: 0.470nMAssay Description:Displacement of [3H]-estradiol from Estrogen receptor betaMore data for this Ligand-Target Pair
Affinity DataKi: 0.470nM ΔG°: -12.6kcal/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Recombinant ER-α or ER-β ligand binding domain (LBD) was combined with [3H]E2 (PerkinElmer, Waltham, Mass.) in buffer A (10 mM Tris, pH 7.4...More data for this Ligand-Target Pair
Affinity DataKi: 0.490nMAssay Description:Antagonistic activity against estrogen receptor beta in presence of 0.1 nM estradiolMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Binding affinity for estrogen receptor betaMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]17beta-estradiol from ERbetaMore data for this Ligand-Target Pair
Affinity DataKi: 0.510nMAssay Description:Displacement of [3H]estradiol from ERbeta after 4 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 0.530nM ΔG°: -12.5kcal/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataKi: 0.570nMAssay Description:Displacement of [3H]estradiol from human full-length ERbeta receptor by competitive radiometric binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.630nMAssay Description:Displacement of [3H]estradiol from human recombinant ERbetaMore data for this Ligand-Target Pair
Affinity DataKi: 0.630nMAssay Description:In vitro displacement of 0.5 nM [3H]17-beta-estradiol from human Estrogen receptor betaMore data for this Ligand-Target Pair
Affinity DataKi: 0.630nM ΔG°: -12.4kcal/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataKi: 0.660nM ΔG°: -12.4kcal/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nM ΔG°: -12.4kcal/molepH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair
Affinity DataKi: 0.700nM ΔG°: -12.4kcal/mole EC50: 1.14nMpH: 7.5 T: 2°CAssay Description:The binding affinities were determined by a competitive radiometric binding assay using [3H]estradiol as tracer. The Kd for 3H-estradiol was determin...More data for this Ligand-Target Pair