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Found 15 of ic50 for UniProtKB: P05182
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen's University

Curated by ChEMBL
LigandPNGBDBM50183063((2R,4R)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of rat liver CYP2E1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen's University

Curated by ChEMBL
LigandPNGBDBM31682(imidazole-dioxolane, 32)
Affinity DataIC50:  3.60E+3nMpH: 7.4Assay Description:CYP2E1 hydroxylation of p-nitrophenol was determined by the spectrophotometric measurement of 4-nitrocatechol. Briefly, reaction mixture consisting o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen's University

Curated by ChEMBL
LigandPNGBDBM50183062(1-((2-(2-(4-chlorophenyl)ethyl)-1,3-dioxolan-2-yl)...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of rat liver CYP2E1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen's University

Curated by ChEMBL
LigandPNGBDBM50183058((2R,4S)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of rat liver CYP2E1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen's University

Curated by ChEMBL
LigandPNGBDBM50183068(1-((2-(4-chlorophenethyl)-1,3-dithiolan-2-yl)methy...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of rat liver CYP2E1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen's University

Curated by ChEMBL
LigandPNGBDBM50183064((2S,4S)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of rat liver CYP2E1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen's University

Curated by ChEMBL
LigandPNGBDBM50183069((2S,4R)-2-[2-(4-chlorophenyl)ethyl]-2-[(1H-imidazo...)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of rat liver CYP2E1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen's University

Curated by ChEMBL
LigandPNGBDBM31672(imidazole-dioxolane, 24)
Affinity DataIC50: >1.00E+5nMpH: 7.4Assay Description:CYP2E1 hydroxylation of p-nitrophenol was determined by the spectrophotometric measurement of 4-nitrocatechol. Briefly, reaction mixture consisting o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen's University

Curated by ChEMBL
LigandPNGBDBM31669(imidazole-dioxolane, 21)
Affinity DataIC50: >1.00E+5nMpH: 7.4Assay Description:CYP2E1 hydroxylation of p-nitrophenol was determined by the spectrophotometric measurement of 4-nitrocatechol. Briefly, reaction mixture consisting o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen's University

Curated by ChEMBL
LigandPNGBDBM31665(imidazole-dioxolane, 17)
Affinity DataIC50: >1.00E+5nMpH: 7.4Assay Description:CYP2E1 hydroxylation of p-nitrophenol was determined by the spectrophotometric measurement of 4-nitrocatechol. Briefly, reaction mixture consisting o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen's University

Curated by ChEMBL
LigandPNGBDBM31664(imidazole-dioxolane, 16)
Affinity DataIC50: >1.00E+5nMpH: 7.4Assay Description:CYP2E1 hydroxylation of p-nitrophenol was determined by the spectrophotometric measurement of 4-nitrocatechol. Briefly, reaction mixture consisting o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen's University

Curated by ChEMBL
LigandPNGBDBM31658(imidazole-dioxolane, 10)
Affinity DataIC50: >1.00E+5nMpH: 7.4 T: 2°CAssay Description:CYP2E1 hydroxylation of p-nitrophenol was determined by the spectrophotometric measurement of 4-nitrocatechol. Briefly, reaction mixture consisting o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen's University

Curated by ChEMBL
LigandPNGBDBM31657(imidazole-dioxolane, 9)
Affinity DataIC50: >1.00E+5nMpH: 7.4 T: 2°CAssay Description:CYP2E1 hydroxylation of p-nitrophenol was determined by the spectrophotometric measurement of 4-nitrocatechol. Briefly, reaction mixture consisting o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen's University

Curated by ChEMBL
LigandPNGBDBM31652(imidazole-dioxolane, 3)
Affinity DataIC50: >1.00E+5nMpH: 7.4 T: 2°CAssay Description:CYP2E1 hydroxylation of p-nitrophenol was determined by the spectrophotometric measurement of 4-nitrocatechol. Briefly, reaction mixture consisting o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2E1(Rattus norvegicus (rat))
Queen's University

Curated by ChEMBL
LigandPNGBDBM31656(imidazole-dioxolane, 8)
Affinity DataIC50: >1.00E+5nMpH: 7.4 T: 2°CAssay Description:CYP2E1 hydroxylation of p-nitrophenol was determined by the spectrophotometric measurement of 4-nitrocatechol. Briefly, reaction mixture consisting o...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed