PrimarySearch_ki

PrimarySearch_ki

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Found 10 hits affinity hit(s) for enzyme = Protein Kinase C, alpha with UniProtKB: P17252
Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	pH	Temp °C
Protein Kinase C, alpha Homo sapiens (Human)	maleimide derivative, 12	DrugBank GoogleScholar PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	n/a	n/a	0.9	n/a	n/a	7.4	23
Novartis	maleimide derivative, 12	DrugBank GoogleScholar PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	J Med Chem. 52: 6193-6 (2009)
Protein Kinase C, alpha Homo sapiens (Human)	AEB071 (Sotrastaurin)	DrugBank GoogleScholar PDB UniProtKB/SwissProt	CSLS PDB PubChem	PDB PubMed	n/a	n/a	2.1	n/a	n/a	7.4	23
Novartis	AEB071 (Sotrastaurin)	DrugBank GoogleScholar PDB UniProtKB/SwissProt	CSLS PDB PubChem	PDB PubMed	J Med Chem. 52: 6193-6 (2009)
Protein Kinase C, alpha Homo sapiens (Human)	maleimide derivative, 10	DrugBank GoogleScholar PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	n/a	n/a	2.2	n/a	n/a	7.4	23
Novartis	maleimide derivative, 10	DrugBank GoogleScholar PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	J Med Chem. 52: 6193-6 (2009)
Protein Kinase C, alpha Homo sapiens (Human)	BIM-1 (2-[1-(3-dimethylaminopropyl)-indol-3-yl]-3-(indol-...)	DrugBank GoogleScholar PDB UniProtKB/SwissProt	B.MOAD CSLS DrugBank PDB PubChem	PubMed	n/a	n/a	2.3	n/a	n/a	7.4	23
Novartis		DrugBank GoogleScholar PDB UniProtKB/SwissProt	B.MOAD CSLS DrugBank PDB PubChem	PubMed	J Med Chem. 52: 6193-6 (2009)
Protein Kinase C, alpha Homo sapiens (Human)	maleimide derivative, 11	DrugBank GoogleScholar PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	n/a	n/a	7.1	n/a	n/a	7.4	23
Novartis	maleimide derivative, 11	DrugBank GoogleScholar PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	J Med Chem. 52: 6193-6 (2009)
Protein Kinase C, alpha Homo sapiens (Human)	maleimide derivative, 9	DrugBank GoogleScholar PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	n/a	n/a	15.0	n/a	n/a	7.4	23
Novartis	maleimide derivative, 9	DrugBank GoogleScholar PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	J Med Chem. 52: 6193-6 (2009)
Protein Kinase C, alpha Homo sapiens (Human)	maleimide derivative, 5	DrugBank GoogleScholar PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	n/a	n/a	73.0	n/a	n/a	7.4	23
Novartis	maleimide derivative, 5	DrugBank GoogleScholar PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	J Med Chem. 52: 6193-6 (2009)
Protein Kinase C, alpha Homo sapiens (Human)	maleimide derivative, 3	DrugBank GoogleScholar PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	n/a	n/a	98.0	n/a	n/a	7.4	23
Novartis	maleimide derivative, 3	DrugBank GoogleScholar PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	J Med Chem. 52: 6193-6 (2009)
Protein Kinase C, alpha Homo sapiens (Human)	maleimide derivative, 4	DrugBank GoogleScholar PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	n/a	n/a	>315.0	n/a	n/a	7.4	23
Novartis	maleimide derivative, 4	DrugBank GoogleScholar PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	J Med Chem. 52: 6193-6 (2009)
Protein Kinase C, alpha Homo sapiens (Human)	maleimide derivative, 13	DrugBank GoogleScholar PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	n/a	n/a	1502.0	n/a	n/a	7.4	23
Novartis	maleimide derivative, 13	DrugBank GoogleScholar PDB UniProtKB/SwissProt	CSLS PubChem	PubMed	J Med Chem. 52: 6193-6 (2009)

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