Compile Data Set for Download or QSAR
maximum 50k data
Found 75 of ic50 for UniProtKB: P00921
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50044311(CHEMBL67511 | TRIFLUOROMETHANE SULFONAMIDE | Trifl...)
Affinity DataIC50: <2nMAssay Description:Inhibition of bovine carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50004262(CHEMBL1438301)
Affinity DataIC50:  11nMAssay Description:Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50068231(CHEMBL3403326)
Affinity DataIC50:  35nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50004258(CHEMBL3237498)
Affinity DataIC50:  52nMAssay Description:Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50068223(CHEMBL3403323)
Affinity DataIC50:  57nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50175007(CHEMBL371870 | phenyldifluoromethanesulfonamide)
Affinity DataIC50:  58nMAssay Description:Inhibition of bovine carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50068229(CHEMBL3403327)
Affinity DataIC50:  100nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM16661(1-N-(4-fluorobenzene)benzene-1,4-disulfonamide | a...)
Affinity DataIC50:  100nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50068225(CHEMBL3403324)
Affinity DataIC50:  134nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50068227(CHEMBL3403325)
Affinity DataIC50:  152nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataIC50:  180nMpH: 7.2Assay Description:This was assay performed using buffer containing Tris and HEPES at the pH of 7.2-7.9 and a total concentration of 20 mM. 96-well plates were filled w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50247721(4-fluoro-N-(4-sulfamoylbenzyl)benzenesulfonamide |...)
Affinity DataIC50:  215nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50004252(CHEMBL3237493)
Affinity DataIC50:  220nMAssay Description:Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50517903(CHEMBL4542353)
Affinity DataIC50:  220nMAssay Description:Inhibition of bovine carbonic anhydrase 2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50068226(CHEMBL1607835)
Affinity DataIC50:  241nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50004255(CHEMBL1330833)
Affinity DataIC50:  490nMAssay Description:Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50068218(CHEMBL3403318)
Affinity DataIC50:  544nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50175005(CHEMBL369953 | phenylmethanesulfonamide)
Affinity DataIC50:  630nMAssay Description:Inhibition of bovine carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50044318(CHEMBL305268 | METHANESULFONAMIDE | aminosulfane d...)
Affinity DataIC50:  650nMAssay Description:Inhibition of bovine carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50068221(CHEMBL3403321)
Affinity DataIC50:  656nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50068228(CHEMBL3403317)
Affinity DataIC50:  691nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50068220(CHEMBL3403320)
Affinity DataIC50:  821nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataIC50:  960nMAssay Description:Inhibition of bovine carbonic anhydrase 2 assessed as hydrolysis of p-nitrophenyl acetate after 30 mins by spectrophotometric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM10880(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)
Affinity DataIC50:  960nMAssay Description:Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50004260(CHEMBL3237499)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM222428(N'',N'''-Bis[(E)-(4-nitrophenyl)methylidene]ca...)
Affinity DataIC50:  1.33E+3nMpH: 7.4 T: 2°CAssay Description:In this assay, 4-nitrophenyl acetate (4-NPA), a colorless compound, was hydrolyzed to 4-nitrophenol and CO2. The reaction was followed by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM222430(N'',N'''-Bis[(E)-(2-chloro-5-nitrophenyl)methy...)
Affinity DataIC50:  1.37E+3nMpH: 7.4 T: 2°CAssay Description:In this assay, 4-nitrophenyl acetate (4-NPA), a colorless compound, was hydrolyzed to 4-nitrophenol and CO2. The reaction was followed by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM222435(N'',N'''-Bis[(E)-(2,6-dichlorophenyl)methylide...)
Affinity DataIC50:  1.46E+3nMpH: 7.4 T: 2°CAssay Description:In this assay, 4-nitrophenyl acetate (4-NPA), a colorless compound, was hydrolyzed to 4-nitrophenol and CO2. The reaction was followed by measuring t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM222429(N'',N'''-Bis[(E)-(2-nitrophenyl)methylidene]ca...)
Affinity DataIC50:  1.85E+3nMpH: 7.4 T: 2°CAssay Description:In this assay, 4-nitrophenyl acetate (4-NPA), a colorless compound, was hydrolyzed to 4-nitrophenol and CO2. The reaction was followed by measuring t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM10888(1,2-benzoxazol-3-ylmethanesulfonamide | CHEMBL750 ...)
Affinity DataIC50:  1.86E+3nMpH: 7.4 T: 2°CAssay Description:In this assay, 4-nitrophenyl acetate (4-NPA), a colorless compound, was hydrolyzed to 4-nitrophenol and CO2. The reaction was followed by measuring t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM222431(N'',N'''-Bis[(E)-(4-bromophenyl)methylidene]ca...)
Affinity DataIC50:  2.32E+3nMpH: 7.4 T: 2°CAssay Description:In this assay, 4-nitrophenyl acetate (4-NPA), a colorless compound, was hydrolyzed to 4-nitrophenol and CO2. The reaction was followed by measuring t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM222433(N'',N'''-Bis[(E)-(2-chlorophenyl)methylidene]c...)
Affinity DataIC50:  2.33E+3nMpH: 7.4 T: 2°CAssay Description:In this assay, 4-nitrophenyl acetate (4-NPA), a colorless compound, was hydrolyzed to 4-nitrophenol and CO2. The reaction was followed by measuring t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM222434(N'',N'''-Bis[(E)-(2,4-dichlorophenyl)methylide...)
Affinity DataIC50:  2.67E+3nMpH: 7.4 T: 2°CAssay Description:In this assay, 4-nitrophenyl acetate (4-NPA), a colorless compound, was hydrolyzed to 4-nitrophenol and CO2. The reaction was followed by measuring t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM222432(N'',N'''-Bis[(E)-(2-bromophenyl)methylidene]ca...)
Affinity DataIC50:  3.96E+3nMpH: 7.4 T: 2°CAssay Description:In this assay, 4-nitrophenyl acetate (4-NPA), a colorless compound, was hydrolyzed to 4-nitrophenol and CO2. The reaction was followed by measuring t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50004259(CHEMBL1494785)
Affinity DataIC50:  5.58E+3nMAssay Description:Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50004253(CHEMBL3237494)
Affinity DataIC50:  5.64E+3nMAssay Description:Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50004257(CHEMBL3237497)
Affinity DataIC50:  9.76E+3nMAssay Description:Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50004263(CHEMBL3237501)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50004261(CHEMBL3237500)
Affinity DataIC50:  1.34E+4nMAssay Description:Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50004251(CHEMBL3237492)
Affinity DataIC50:  1.35E+4nMAssay Description:Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50004256(CHEMBL3237496)
Affinity DataIC50:  1.42E+4nMAssay Description:Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM193814(N-(4-(bis(5-chloro-1H-indol-3-yl)methyl)phenyl)-2-...)
Affinity DataIC50:  1.43E+4nMpH: 7.2Assay Description:This was assay performed using buffer containing Tris and HEPES at the pH of 7.2-7.9 and a total concentration of 20 mM. 96-well plates were filled w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM193812(N-(4-(bis(5-chloro-1H-indol-3-yl)methyl)phenyl)-2,...)
Affinity DataIC50:  1.56E+4nMpH: 7.2Assay Description:This was assay performed using buffer containing Tris and HEPES at the pH of 7.2-7.9 and a total concentration of 20 mM. 96-well plates were filled w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM193811(N-(4-(bis(5-chloro-1H-indol-3-yl)methyl)phenyl)-2,...)
Affinity DataIC50:  1.63E+4nMpH: 7.2Assay Description:This was assay performed using buffer containing Tris and HEPES at the pH of 7.2-7.9 and a total concentration of 20 mM. 96-well plates were filled w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50004254(CHEMBL3237495)
Affinity DataIC50:  1.71E+4nMAssay Description:Inhibition of bovine erythrocyte carbonic anhydrase 2 using p-nitrophenyl acetate as substrate preincubated for 10 mins before substrate addition mea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM193801(N-(4-(bis(5-bromo-1H-indol-3-yl)methyl)phenyl)-3,5...)
Affinity DataIC50:  1.88E+4nMpH: 7.2Assay Description:This was assay performed using buffer containing Tris and HEPES at the pH of 7.2-7.9 and a total concentration of 20 mM. 96-well plates were filled w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM193816(N-(4-(bis(5-chloro-1H-indol-3-yl)methyl)phenyl)-3,...)
Affinity DataIC50:  2.02E+4nMpH: 7.2Assay Description:This was assay performed using buffer containing Tris and HEPES at the pH of 7.2-7.9 and a total concentration of 20 mM. 96-well plates were filled w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM193797(N-(4-(bis(5-bromo-1H-indol-3-yl)methyl)phenyl)-2,4...)
Affinity DataIC50:  2.89E+4nMpH: 7.2Assay Description:This was assay performed using buffer containing Tris and HEPES at the pH of 7.2-7.9 and a total concentration of 20 mM. 96-well plates were filled w...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM152666
Affinity DataIC50:  3.01E+4nMpH: 7.2Assay Description:This was assay performed using buffer containing Tris and HEPES at the pH of 7.2-7.9 and a total concentration of 20 mM. 96-well plates were filled w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Bos taurus)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM152668
Affinity DataIC50:  3.23E+4nMpH: 7.2Assay Description:This was assay performed using buffer containing Tris and HEPES at the pH of 7.2-7.9 and a total concentration of 20 mM. 96-well plates were filled w...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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