Found 969 of ic50 data for polymerid = 4401,50000333,50002394,50003935,50004196,50004283,50004389,50004529,50004587,50004599
Affinity DataIC50: 1nMAssay Description:Inhibitory activity against serine Beta-lactamase derived from Staphylococcus aureusMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:A buffer consisting of 0.1 M sodium phosphate (pH 7.0), 10 mM NaHCO3, and 0.005% Triton X-100 was used for all enzymes. The chromogenic substrate nit...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:A buffer consisting of 0.1 M sodium phosphate (pH 7.0), 10 mM NaHCO3, and 0.005% Triton X-100 was used for all enzymes. The chromogenic substrate nit...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:In vitro inhibitory activity against Class C (Amp-C) beta-LactamasesMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:In vitro inhibitory activity against Class C (Amp-C) beta-LactamasesMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
TargetBeta-lactamase(Escherichia coli)
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of Escherichia coli CTX-M-15More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:A buffer consisting of 0.1 M sodium phosphate (pH 7.0), 10 mM NaHCO3, and 0.005% Triton X-100 was used for all enzymes. The chromogenic substrate nit...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90nMAssay Description:Inhibitory activity against Class C beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibitory activity against Class C beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:A buffer consisting of 0.1 M sodium phosphate (pH 7.0), 10 mM NaHCO3, and 0.005% Triton X-100 was used for all enzymes. The chromogenic substrate nit...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Compound was evaluated for beta-lactamase inhibition activity of Enterobacter cloacae after 15 min of preincubation with the enzyme at 37 degree CMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibitory activity against serine Beta-lactamase TEM derived from Staphylococcus aureusMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of Bacillus clausii NR beta-lactamase BCL1 expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
Affinity DataIC50: 4.10nMAssay Description:A buffer consisting of 0.1 M sodium phosphate (pH 7.0), 10 mM NaHCO3, and 0.005% Triton X-100 was used for all enzymes. The chromogenic substrate nit...More data for this Ligand-Target Pair
Affinity DataIC50: 4.40nMAssay Description:A buffer consisting of 0.1 M sodium phosphate (pH 7.0), 10 mM NaHCO3, and 0.005% Triton X-100 was used for all enzymes. The chromogenic substrate nit...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibitory activity against Class C beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Pseudomonas aeruginosa beta lactamase AmpCMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity against Class C (Amp-C) beta-LactamasesMore data for this Ligand-Target Pair
Affinity DataIC50: 5.5nMAssay Description:Inhibitory activity against Class C beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of Enterobacter cloacae AmpCMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:In vitro inhibitory activity against Class C (Amp-C) beta-LactamasesMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30nMAssay Description:A buffer consisting of 0.1 M sodium phosphate (pH 7.0), 10 mM NaHCO3, and 0.005% Triton X-100 was used for all enzymes. The chromogenic substrate nit...More data for this Ligand-Target Pair
Affinity DataIC50: 7.5nMAssay Description:Inhibition of Pseudomonas aeruginosa beta lactamase AmpCMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Inhibitory activity against class A TEM-1 beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:A buffer consisting of 0.1 M sodium phosphate (pH 7.0), 10 mM NaHCO3, and 0.005% Triton X-100 was used for all enzymes. The chromogenic substrate nit...More data for this Ligand-Target Pair
Affinity DataIC50: 8.30nMAssay Description:Inhibitory activity against class A TEM-1 beta-lactamaseMore data for this Ligand-Target Pair
TargetBeta-lactamase(Escherichia coli)
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Johnson & Johnson Pharmaceutical Research And Development
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Inhibition of Escherichia coli CTX-M-15More data for this Ligand-Target Pair
Affinity DataIC50: 9.30nMAssay Description:A buffer consisting of 0.1 M sodium phosphate (pH 7.0), 10 mM NaHCO3, and 0.005% Triton X-100 was used for all enzymes. The chromogenic substrate nit...More data for this Ligand-Target Pair
Affinity DataIC50: 9.40nMAssay Description:Inhibitory activity against class A TEM-1 beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataIC50: 9.60nMAssay Description:Inhibition of Pseudomonas aeruginosa beta lactamase AmpCMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:A buffer consisting of 0.1 M sodium phosphate (pH 7.0), 10 mM NaHCO3, and 0.005% Triton X-100 was used for all enzymes. The chromogenic substrate nit...More data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibitory activity against Class C beta-lactamaseMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:A buffer consisting of 0.1 M sodium phosphate (pH 7.0), 10 mM NaHCO3, and 0.005% Triton X-100 was used for all enzymes. The chromogenic substrate nit...More data for this Ligand-Target Pair