TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 600nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 3.10E+3nMpH: 7.0Assay Description:Inhibition of human placental HexA using MUGS substrate incubated for 1 to 2 hrs at pH 7.0 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 6.00E+3nMAssay Description:Competitive inhibition of human beta-N-acetyl-D-hexosaminidase-A using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate assessed as re...More data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 8.50E+3nMpH: 4.5Assay Description:Inhibition of HexA alpha G269S mutant in ATSD patient fibroblasts using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 8.90E+3nMpH: 4.5Assay Description:Inhibition of human placental HexA using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMpH: 7.0Assay Description:Inhibition of human placental HexA using MUGS substrate incubated for 1 to 2 hrs at pH 7.0 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMpH: 4.5Assay Description:Inhibition of HexA in normal human fibroblasts using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha/beta(Homo sapiens (Human))
Genetics and Genome Biology, SickKids, PGCRL 686 Bay Street, Toronto, Ontario M5G 0A4, Canada.
Curated by ChEMBL
Genetics and Genome Biology, SickKids, PGCRL 686 Bay Street, Toronto, Ontario M5G 0A4, Canada.
Curated by ChEMBL
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of beta-N-acetylhexosaminidase (unknown origin)More data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 1.60E+4nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMpH: 4.5Assay Description:Inhibition of HexA in normal human fibroblasts using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMpH: 4.5Assay Description:Inhibition of HexA alpha G269S mutant in ATSD patient fibroblasts using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMpH: 4.5Assay Description:Inhibition of human placental HexA using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometryMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 3.10E+4nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of beta-hexosaminidase alpha in human skin fibroblast lysate using 4-MU-N-acetyl-beta-D-glucosaminide-6-sulfate sodium salt as substrate a...More data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of beta-hexosaminidase alpha in human skin fibroblast lysate using 4-MU-N-acetyl-beta-D-glucosaminide-6-sulfate sodium salt as substrate a...More data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 1.08E+5nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 1.38E+5nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: >1.60E+5nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha/beta(Homo sapiens (Human))
Genetics and Genome Biology, SickKids, PGCRL 686 Bay Street, Toronto, Ontario M5G 0A4, Canada.
Curated by ChEMBL
Genetics and Genome Biology, SickKids, PGCRL 686 Bay Street, Toronto, Ontario M5G 0A4, Canada.
Curated by ChEMBL
Affinity DataIC50: 3.15E+5nMAssay Description:Inhibition of beta-hexosaminidase alpha/beta in human skin fibroblast lysate using 4-MU-(2-acetamido-2-deoxy)-beta-D-glucopyranoside as substrate ass...More data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha/beta(Homo sapiens (Human))
Genetics and Genome Biology, SickKids, PGCRL 686 Bay Street, Toronto, Ontario M5G 0A4, Canada.
Curated by ChEMBL
Genetics and Genome Biology, SickKids, PGCRL 686 Bay Street, Toronto, Ontario M5G 0A4, Canada.
Curated by ChEMBL
Affinity DataIC50: 3.15E+5nMAssay Description:Inhibition of beta-hexosaminidase alpha/beta in human skin fibroblast lysate using 4-MU-(2-acetamido-2-deoxy)-beta-D-glucopyranoside as substrate ass...More data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: 3.50E+5nMAssay Description:Inhibition of beta-hexosaminidase alpha in human skin fibroblast lysate using 4-MU-N-acetyl-beta-D-glucosaminide-6-sulfate sodium salt as substrate a...More data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: >4.10E+5nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: >5.60E+5nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: >9.40E+5nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: >1.40E+6nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Universit£ d'Orl£ans & CNRS
Curated by ChEMBL
Affinity DataIC50: >2.10E+6nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair