Compile Data Set for Download or QSAR
maximum 50k data
Found 41 of ic50 for UniProtKB: P06865
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM50235813(CHEMBL4097052)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM68271(M-31850)
Affinity DataIC50:  600nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM18512(5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...)
Affinity DataIC50:  3.10E+3nMpH: 7.0Assay Description:Inhibition of human placental HexA using MUGS substrate incubated for 1 to 2 hrs at pH 7.0 by spectrofluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM68272(LU79953)
Affinity DataIC50:  4.60E+3nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM50491601(CHEMBL2333316)
Affinity DataIC50:  6.00E+3nMAssay Description:Competitive inhibition of human beta-N-acetyl-D-hexosaminidase-A using 4-Methylumbelliferyl N-acetyl-beta-D-glucosaminide as substrate assessed as re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM18512(5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...)
Affinity DataIC50:  8.50E+3nMpH: 4.5Assay Description:Inhibition of HexA alpha G269S mutant in ATSD patient fibroblasts using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM18512(5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...)
Affinity DataIC50:  8.90E+3nMpH: 4.5Assay Description:Inhibition of human placental HexA using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM18788(6-ethyl-5-phenylpyrimidine-2,4-diamine | CHEMBL221...)
Affinity DataIC50:  1.10E+4nMpH: 7.0Assay Description:Inhibition of human placental HexA using MUGS substrate incubated for 1 to 2 hrs at pH 7.0 by spectrofluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM18512(5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...)
Affinity DataIC50:  1.40E+4nMpH: 4.5Assay Description:Inhibition of HexA in normal human fibroblasts using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM50089680(CHEMBL3577321)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha/beta(Homo sapiens (Human))
Genetics and Genome Biology, SickKids, PGCRL 686 Bay Street, Toronto, Ontario M5G 0A4, Canada.

Curated by ChEMBL
LigandPNGBDBM18512(5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of beta-N-acetylhexosaminidase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM68270(5141402)
Affinity DataIC50:  1.60E+4nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM18512(5-(4-chlorophenyl)-6-ethylpyrimidine-2,4-diamine |...)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM18780(6-ethyl-5-(4-methoxyphenyl)pyrimidine-2,4-diamine ...)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM50106194(1,3-dioxo-1H-benz[de]isoquinoline | 1,8-Naphthalim...)
Affinity DataIC50:  1.80E+4nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM50089676(CHEMBL3577317)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM18788(6-ethyl-5-phenylpyrimidine-2,4-diamine | CHEMBL221...)
Affinity DataIC50:  2.70E+4nMpH: 4.5Assay Description:Inhibition of HexA in normal human fibroblasts using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM18788(6-ethyl-5-phenylpyrimidine-2,4-diamine | CHEMBL221...)
Affinity DataIC50:  2.70E+4nMpH: 4.5Assay Description:Inhibition of HexA alpha G269S mutant in ATSD patient fibroblasts using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM18788(6-ethyl-5-phenylpyrimidine-2,4-diamine | CHEMBL221...)
Affinity DataIC50:  3.00E+4nMpH: 4.5Assay Description:Inhibition of human placental HexA using MUGS substrate incubated for 1 to 2 hrs at pH 4.5 by spectrofluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM68269(M-31867)
Affinity DataIC50:  3.10E+4nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM18788(6-ethyl-5-phenylpyrimidine-2,4-diamine | CHEMBL221...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM50089681(CHEMBL3577322)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM18779(6-ethyl-5-(4-methylphenyl)pyrimidine-2,4-diamine |...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM50089682(CHEMBL3577323)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM50089683(CHEMBL3577324)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM50190645(CHEMBL3982827)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of beta-hexosaminidase alpha in human skin fibroblast lysate using 4-MU-N-acetyl-beta-D-glucosaminide-6-sulfate sodium salt as substrate a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM50190644(CHEMBL3983808)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of beta-hexosaminidase alpha in human skin fibroblast lysate using 4-MU-N-acetyl-beta-D-glucosaminide-6-sulfate sodium salt as substrate a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM68268(M-31862)
Affinity DataIC50:  1.08E+5nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM68267(M-31860)
Affinity DataIC50:  1.38E+5nMT: 2°CAssay Description:Enzyme assay based on 4-MU substrates with HTS to identify inhibitory compounds for Hex.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM50235812(CHEMBL4085739)
Affinity DataIC50: >1.60E+5nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM50089679(CHEMBL3577320)
Affinity DataIC50:  1.80E+5nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha/beta(Homo sapiens (Human))
Genetics and Genome Biology, SickKids, PGCRL 686 Bay Street, Toronto, Ontario M5G 0A4, Canada.

Curated by ChEMBL
LigandPNGBDBM50190645(CHEMBL3982827)
Affinity DataIC50:  3.15E+5nMAssay Description:Inhibition of beta-hexosaminidase alpha/beta in human skin fibroblast lysate using 4-MU-(2-acetamido-2-deoxy)-beta-D-glucopyranoside as substrate ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha/beta(Homo sapiens (Human))
Genetics and Genome Biology, SickKids, PGCRL 686 Bay Street, Toronto, Ontario M5G 0A4, Canada.

Curated by ChEMBL
LigandPNGBDBM50190644(CHEMBL3983808)
Affinity DataIC50:  3.15E+5nMAssay Description:Inhibition of beta-hexosaminidase alpha/beta in human skin fibroblast lysate using 4-MU-(2-acetamido-2-deoxy)-beta-D-glucopyranoside as substrate ass...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM50190643(CHEMBL3933402)
Affinity DataIC50:  3.50E+5nMAssay Description:Inhibition of beta-hexosaminidase alpha in human skin fibroblast lysate using 4-MU-N-acetyl-beta-D-glucosaminide-6-sulfate sodium salt as substrate a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM50089674(CHEMBL3577315)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM50089673(CHEMBL3577314)
Affinity DataIC50: >4.00E+5nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM50089677(CHEMBL3577318)
Affinity DataIC50: >4.10E+5nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM18775(5-(4-chlorophenyl)-6-methylpyrimidine-2,4-diamine ...)
Affinity DataIC50: >5.60E+5nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM50089675(CHEMBL3577316)
Affinity DataIC50: >9.40E+5nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM50089678(CHEMBL3577319)
Affinity DataIC50: >1.40E+6nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-hexosaminidase subunit alpha(Homo sapiens (Human))
Universit£ d'Orl£ans & CNRS

Curated by ChEMBL
LigandPNGBDBM50089672(CHEMBL3577313)
Affinity DataIC50: >2.10E+6nMAssay Description:Inhibition of human placental HexA using pNPGlcNAc substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed