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Found 24 of ec50 for UniProtKB: P06537
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19224((S)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...)
Affinity DataEC50:  3nMAssay Description:Inhibition of mouse glutamine synthetase by GR-mediated transactivation in C2C12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19190((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)
Affinity DataEC50:  3.40nMAssay Description:Inhibition of mouse glutamine synthetase by GR-mediated transactivation in C2C12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19210((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...)
Affinity DataEC50:  3.70nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165102((S)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5...)
Affinity DataEC50:  5nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19202((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...)
Affinity DataEC50:  5.20nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19190((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...)
Affinity DataEC50:  5.70nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19202((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...)
Affinity DataEC50:  8.30nMAssay Description:Inhibition of mouse glutamine synthetase by GR-mediated transactivation in C2C12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19224((S)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...)
Affinity DataEC50:  11nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165104((R)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5...)
Affinity DataEC50:  12nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19199((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...)
Affinity DataEC50:  15nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19210((1S)-1-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4...)
Affinity DataEC50:  17nMAssay Description:Inhibition of mouse glutamine synthetase by GR-mediated transactivation in C2C12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165106((R)-(5-Chloro-thiophen-2-yl)-[(4aR,5S)-1-(4-fluoro...)
Affinity DataEC50:  17nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165105((R)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5...)
Affinity DataEC50:  21nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19192((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...)
Affinity DataEC50:  22nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165102((S)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5...)
Affinity DataEC50:  23nMAssay Description:Inhibition of mouse glutamine synthetase by GR-mediated transactivation in C2C12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165106((R)-(5-Chloro-thiophen-2-yl)-[(4aR,5S)-1-(4-fluoro...)
Affinity DataEC50:  34nMAssay Description:Inhibition of mouse glutamine synthetase by GR-mediated transactivation in C2C12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19220((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...)
Affinity DataEC50:  42nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165103((R)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5...)
Affinity DataEC50:  45nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19223((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...)
Affinity DataEC50:  54nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165100((R)-(2,5-Dichloro-thiophen-3-yl)-[(4aR,5S)-1-(4-fl...)
Affinity DataEC50:  120nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165101((R)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5...)
Affinity DataEC50:  215nMAssay Description:GR-mediated transrepression of IL-6 in peritoneal exudate cells harvested from C57BI/6 miceMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50165104((R)-[(4aR,5S)-1-(4-Fluoro-phenyl)-4a-methyl-4,4a,5...)
Affinity DataEC50:  260nMAssay Description:Inhibition of mouse glutamine synthetase by GR-mediated transactivation in C2C12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM19220((R)-[(4aR,5S)-1-(4-fluorophenyl)-4a-methyl-1H,4H,4...)
Affinity DataEC50:  1.21E+3nMAssay Description:Inhibition of mouse glutamine synthetase by GR-mediated transactivation in C2C12 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucocorticoid receptor(MOUSE)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50153594(CHEMBL3774855)
Affinity DataEC50: >2.00E+4nMAssay Description:Inhibition of mouse GRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed