Compile Data Set for Download or QSAR
maximum 50k data
Found 35 of ic50 data for polymerid = 49000791,49000792,49000793,49000795,50006859
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50403793(CHEMBL2115415)
Affinity DataIC50:  0.720nMAssay Description:The compound was evaluated in vitro for its ability to displace [3H]-SP from Tachykinin receptor 3 of male guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50079412((NKB)Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2 |...)
Affinity DataIC50:  2nMAssay Description:Inhibitory activity against Tachykinin receptor 3 in guinea pig cortical membranes labeled with [125 I][MePhe7]-NKBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50090485(CHEMBL295615 | spiro[(2-hydroxy)indane-1,40-piperi...)
Affinity DataIC50:  2.70nMAssay Description:The compound was evaluated in vitro for its ability to displace [3H]-SP from Tachykinin receptor 3 of male guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50050641(CHEMBL45340 | PD-161182 | [(R)-2-(2,3-Difluoro-phe...)
Affinity DataIC50:  3.70nMAssay Description:Compound was tested for binding affinity towards Tachykinin receptor 3 binding sites in guinea pig cortical membranes using [125I][MePhe7]-NKB as rad...More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50050641(CHEMBL45340 | PD-161182 | [(R)-2-(2,3-Difluoro-phe...)
Affinity DataIC50:  4nMAssay Description:Inhibitory activity against Tachykinin receptor 3 in guinea pig cortical membranes labeled with [125 I]-[MePhe7]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50050649(CHEMBL444832 | {(S)-1-[(R)-1-Methyl-2-phenyl-1-(7-...)
Affinity DataIC50:  9nMAssay Description:Binding affinity for NK3 receptor binding sites in guinea pig cortical membranes by using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50050649(CHEMBL444832 | {(S)-1-[(R)-1-Methyl-2-phenyl-1-(7-...)
Affinity DataIC50:  9nMAssay Description:Inhibitory activity against Tachykinin receptor 3 in guinea pig cortical membranes labeled with [125 I]-[MePhe7]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50079412((NKB)Asp-Met-His-Asp-Phe-Phe-Val-Gly-Leu-Met-NH2 |...)
Affinity DataIC50:  10nMAssay Description:Inhibitory activity against binding of [125I]-[MePhe7]-NKB SP to tachykinin NK-3 receptor in guinea pig cortical membranes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50403790(CHEMBL2114963)
Affinity DataIC50:  11nMAssay Description:The compound was evaluated in vitro for its ability to displace [3H]-SP from Tachykinin receptor 3 of male guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50052524((S)-N-((S)-1-{[(S)-1-({[(S)-1-((S)-1-Carbamoyl-3-m...)
Affinity DataIC50:  12nMAssay Description:Inhibitory activity against Tachykinin receptor 3 in guinea pig cortical membranes labeled with [125I]-[MePhe7]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50050652(CHEMBL47146 | PD-160946 | [(R)-2-(2-Fluoro-phenyl)...)
Affinity DataIC50:  14nMAssay Description:Compound was tested for binding affinity towards Tachykinin receptor 3 binding sites in guinea pig cortical membranes using [125I]-[MePhe7]-Neurokini...More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50050652(CHEMBL47146 | PD-160946 | [(R)-2-(2-Fluoro-phenyl)...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against Tachykinin receptor 3 in guinea pig cortical membranes labeled with [125 I]-[MePhe7]More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50282774(CHEMBL295301 | {(S)-1-[(R)-1-(8-Carbamoyl-octylcar...)
Affinity DataIC50:  15nMAssay Description:Binding affinity for NK3 receptor binding sites in guinea pig cortical membranes by using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50090487(CHEMBL298247 | spiro[(2-hydroxy)indane-1,40-piperi...)
Affinity DataIC50:  17nMAssay Description:The compound was evaluated in vitro for its ability to displace [3H]-SP from Tachykinin receptor 3 of male guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50175494(1-{2-[(R)-3-(3,4-Dichloro-phenyl)-1-(3,4,5-trimeth...)
Affinity DataIC50:  21nMAssay Description:NK3 IC50 determined using [125I]-Bolton Hunter labeled eledoisin at NK3 receptors from guinea pig cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50282782(CHEMBL297327 | {(S)-1-[(R)-1-(8-Hydroxy-octylcarba...)
Affinity DataIC50:  22nMAssay Description:Binding affinity for NK3 receptor binding sites in guinea pig cortical membranes by using [125I][MePhe7]-NKB as radioligandMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50050642(CHEMBL296014 | {(S)-1-[(R)-1-(8-Hydroxy-octylcarba...)
Affinity DataIC50:  22nMAssay Description:Inhibitory activity against Tachykinin receptor 3 in guinea pig cortical membranes labeled with [125 I][MePhe7]-NKBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50071484(CHEMBL308148 | N-[(R)-4-(4-Acetylamino-4-phenyl-pi...)
Affinity DataIC50:  208nMAssay Description:NK3 IC50 determined using [125I]-Bolton Hunter labeled eledoisin at NK3 receptors from guinea pig cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50283257((S)-2-[2-((S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-4...)
Affinity DataIC50:  276nMAssay Description:Concentration producing half-maximal inhibition of specific binding of [3H]-Senktide to Tachykinin receptor 3 in the guinea pig cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50291261((S)-(+)-N-((3-[1-Benzoyl-3-(3,4-dichlorophenyl)pip...)
Affinity DataIC50:  320nMAssay Description:Ability to displace [3H]senktide succinyl-[Asp9MePhe8]-SP (6-13)} from Tachykinin receptor 3 of guinea pig cerebral cortex membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50403791(CHEMBL2114965)
Affinity DataIC50:  520nMAssay Description:The compound was evaluated in vitro for its ability to displace [3H]-SP from Tachykinin receptor 3 of male guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50283253((S)-2-[2-((S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-4...)
Affinity DataIC50:  533nMAssay Description:Concentration producing half-maximal inhibition of specific binding of [3H]-Senktide to Tachykinin receptor 3 in the guinea pig cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50403792(CHEMBL2115416)
Affinity DataIC50:  660nMAssay Description:The compound was evaluated in vitro for its ability to displace [3H]-SP from Tachykinin receptor 3 of male guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50001450((SP)Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Gly-Leu-Met-NH...)
Affinity DataIC50:  717nMAssay Description:Inhibitory activity against binding of [125I]-[MePhe7]-NKB SP to tachykinin NK-3 receptor in guinea pig cortical membranes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50283250((S)-2-[2-((S)-2-{(S)-2-[(S)-2-((S)-2-Acetylamino-4...)
Affinity DataIC50:  882nMAssay Description:Concentration producing half-maximal inhibition of specific binding of [3H]-Senktide to Tachykinin receptor 3 in the guinea pig cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50090484(CHEMBL46795 | spiro[(2-hydroxy)indane-1,40-piperid...)
Affinity DataIC50: >1.00E+3nMAssay Description:The compound was evaluated in vitro for its ability to displace [3H]-SP from Tachykinin receptor 3 of male guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50090482(CHEMBL295785 | spiro[(2-hydroxy)indane-1,40-piperi...)
Affinity DataIC50: >1.00E+3nMAssay Description:The compound was evaluated in vitro for its ability to displace [3H]-SP from Tachykinin receptor 3 of male guinea pig lung membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50283252((S)-2-[2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-4-carba...)
Affinity DataIC50:  1.13E+3nMAssay Description:Concentration producing half-maximal inhibition of specific binding of [3H]-Senktide to Tachykinin receptor 3 in the guinea pig cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50050675(CHEMBL33650 | [(S)-1-((S)-1-Carbamoyl-2-phenyl-eth...)
Affinity DataIC50:  1.55E+3nMAssay Description:Inhibitory activity against binding of [125I]-[MePhe7]-NKB SP to tachykinin NK-3 receptor in guinea pig cortical membranes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50283255((S)-2-[(5-Oxo-pyrrolidine-2-carbonyl)-amino]-penta...)
Affinity DataIC50:  1.88E+3nMAssay Description:Concentration producing half-maximal inhibition of specific binding of [3H]-Senktide to Tachykinin receptor 3 in the guinea pig cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50287925(2,4-Dibenzyl-morpholin-3-one | CHEMBL441040)
Affinity DataIC50:  4.09E+3nMAssay Description:Inhibitory activity against binding of [125I]-[MePhe7]-NKB SP to tachykinin NK-3 receptor in guinea pig cortical membranes.More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50283966((S)-1-Benzyl-3-(1H-indol-3-ylmethyl)-piperidin-4-o...)
Affinity DataIC50:  8.80E+3nMAssay Description:Binding affinity towards Tachykinin receptor 3 in guinea pig cerebral cortex using [3H]-Senktide as radioligand; Value ranges from 8.2-9.4 uMMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50283960(1-Benzyl-3-(1H-indol-3-ylmethyl)-piperidin-4-one |...)
Affinity DataIC50:  1.00E+4nMAssay Description:Binding affinity towards Tachykinin receptor 3 in guinea pig cerebral cortex using [3H]-Senktide as radioligand; Value ranges from 5.8-14u MMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50000040(((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:NK3 IC50 determined using [125I]-Bolton Hunter labeled eledoisin at NK3 receptors from guinea pig cerebral cortexMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeuromedin-K receptor(GUINEA PIG)
Sankyo

Curated by ChEMBL
LigandPNGBDBM50000040(((2S,3S)-2-Benzhydryl-1-aza-bicyclo[2.2.2]oct-3-yl...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against Tachykinin receptor 3 in guinea pig cortex [125I]-BH-eledoisin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed