Compile Data Set for Download or QSAR
maximum 50k data
Found 61 of ec50 for UniProtKB: P32300
TargetDelta-type/Mu-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50393258(CHEMBL2151734)
Affinity DataEC50:  0nMAssay Description:Agonist activity at MOR/DOR in in NMRI mouse frontal cortex assessed as reduction in spinal cord network activity by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Mu-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50393257(CHEMBL2151735)
Affinity DataEC50:  0nMAssay Description:Agonist activity at MOR/DOR in in NMRI mouse frontal cortex assessed as reduction in spinal cord network activity by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Mu-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50376594(CHEMBL260120)
Affinity DataEC50:  0.00500nMAssay Description:Agonist activity at MOR/DOR in in NMRI mouse frontal cortex assessed as reduction in spinal cord network activity by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50142622(CHEMBL3758292)
Affinity DataEC50:  0.0200nMAssay Description:Agonist activity at delta-opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Mu-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50554766(CHEMBL4795492)
Affinity DataEC50:  0.0316nMAssay Description:Agonist activity at MOR/DOR in wild-type C57BL6 mouse spinal cord membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 60 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Mu-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50554766(CHEMBL4795492)
Affinity DataEC50:  0.0320nMAssay Description:Agonist activity at MOR/DOR in wild-type C57BL6 mouse spinal cord membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 60 mins...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type/Mu-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50393258(CHEMBL2151734)
Affinity DataEC50:  0.287nMAssay Description:Agonist activity at MOR/DOR in in NMRI mouse spinal cord assessed as reduction in spinal cord network activity by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50009185(4-(2-{2-[2-Amino-3-(4-hydroxy-phenyl)-propionylami...)
Affinity DataEC50:  0.331nMAssay Description:Negative logarithm of the molar concentration of delta receptor was determined in mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50038424((S)-3-[(S)-2-((R)-2-Amino-propionylamino)-3-phenyl...)
Affinity DataEC50:  0.360nMAssay Description:Effective concentration was measured towards delta opioid receptor using mouse vas deferens(MVD, delta) bioassay in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50038425((S)-3-((S)-2-{(R)-2-[(2S,3S)-2-Amino-3-(4-hydroxy-...)
Affinity DataEC50:  0.660nMAssay Description:Effective concentration was measured towards delta opioid receptor using mouse vas deferens(MVD, delta) bioassay in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50528969(CHEMBL4458337)
Affinity DataEC50:  0.830nMAssay Description:Agonist activity at mouse delta opioid receptor-1 expressed in CHO cell membranes assessed as [35S]GTPgammaS binding incubated for 60 mins by scintil...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50182942((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-((S...)
Affinity DataEC50:  0.900nMAssay Description:Activity against delta opioid receptor by stimulation of [35S]GTPgammaS binding in CHO-hgamma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Mu-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50393257(CHEMBL2151735)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at MOR/DOR in in NMRI mouse spinal cord assessed as reduction in spinal cord network activity by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Mu-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50000507((R)-2-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-pheny...)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at MOR/DOR in wild-type C57BL6 mouse spinal cord membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 60 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Mu-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50000507((R)-2-[(S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-pheny...)
Affinity DataEC50:  1.80nMAssay Description:Agonist activity at MOR/DOR in wild-type C57BL6 mouse spinal cord membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 60 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50084127((4S,7S,13S)-13-[(2S,3R)-2-Amino-3-(4-hydroxy-2,6-d...)
Affinity DataEC50:  1.80nMAssay Description:Tested for electrically induced smooth muscle contractions from mouse vas deferens expressed in delta opioid receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50133257(CHEMBL334369 | [(2S,3R)-TMT1]DPDPE)
Affinity DataEC50:  1.80nMAssay Description:In vitro bioassay data to determine the effective concentration required for antagonistic activity against Opioid receptor delta 1 in functional assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50001683(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at mouse cloned delta opioid receptor expressed in CHO cells after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50142621(CHEMBL3759292)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at delta-opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Mu-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at MOR/DOR in wild-type C57BL6 mouse spinal cord membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 60 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Mu-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM21015((2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl...)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at MOR/DOR in wild-type C57BL6 mouse spinal cord membranes assessed as stimulation of [35S]-GTPgammaS binding measured after 60 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50182947(4-((S)-2-amino-3-oxo-3-((S)-3-(4-phenyl-1H-imidazo...)
Affinity DataEC50:  3nMAssay Description:Activity against delta opioid receptor by stimulation of [35S]GTPgammaS binding in CHO-hgamma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50142620(CHEMBL3758712)
Affinity DataEC50:  3nMAssay Description:Agonist activity at delta-opioid receptor in mouse vas deferensMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50001683(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataEC50:  4.10nMAssay Description:Effective concentration was measured towards delta opioid receptor using mouse vas deferens(MVD, delta) bioassay in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50001683(13-[2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-7...)
Affinity DataEC50:  4.10nMAssay Description:In vitro bioassay data to determine the effective concentration required for antagonistic activity against Opioid receptor delta 1 in functional assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM60212((4R,4aS,7aR,12bS)-3-(cyclopropylmethyl)-4a,9-bis(o...)
Affinity DataEC50:  4.40nMAssay Description:Agonist activity at mouse DOR expressed in CHO cells after 1.5 hrs by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type/Mu-type opioid receptor(MOUSE)
Vrije Universiteit Brussel

Curated by ChEMBL
LigandPNGBDBM50376593(CHEMBL409225 | SB-0304)
Affinity DataEC50:  6.70nMAssay Description:Agonist activity at MOR/DOR in in NMRI mouse spinal cord assessed as reduction in spinal cord network activity by electrophysiology assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50026762(CHEMBL3331510)
Affinity DataEC50:  7.10nMAssay Description:Agonist activity at mouse delta opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50026764(CHEMBL3331509)
Affinity DataEC50:  7.70nMAssay Description:Agonist activity at mouse delta opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50493749(CHEMBL2437063)
Affinity DataEC50:  9.10nMAssay Description:Agonist activity at mouse cloned delta opioid receptor expressed in CHO cells after 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM21008((4S,7S,13S)-13-[(2S)-2-amino-3-(4-hydroxyphenyl)pr...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at mouse delta opioid receptor-1 expressed in CHO cell membranes assessed as [35S]GTPgammaS binding incubated for 60 mins by scintil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50154036((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-3-(4-phenyl...)
Affinity DataEC50:  19nMAssay Description:Activity against delta opioid receptor by stimulation of [35S]GTPgammaS binding in CHO-hgamma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50182943(4-((S)-2-amino-3-oxo-3-((S)-3-(4-phenyl-1H-imidazo...)
Affinity DataEC50:  22nMAssay Description:Activity against delta opioid receptor by stimulation of [35S]GTPgammaS binding in CHO-hgamma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50066279(CHEMBL2419121)
Affinity DataEC50:  33nMAssay Description:Agonist activity at mouse DOR expressed in CHO cells after 1.5 hrs by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50562078(CHEMBL98593)
Affinity DataEC50:  35nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electric-field induced measured after 5 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50182939((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)-1-((S...)
Affinity DataEC50:  37nMAssay Description:Activity against delta opioid receptor by stimulation of [35S]GTPgammaS binding in CHO-hgamma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50001465((S)-2-[(S)-2-(2-{2-[(S)-2-Amino-3-(4-hydroxy-pheny...)
Affinity DataEC50:  74nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electric-field induced measured after 5 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM21014((2S)-2-amino-N-[(1R)-1-[({[(1S)-1-{N'-[(2S)-2-{2-[...)
Affinity DataEC50:  91nMAssay Description:Agonist activity at mouse delta opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50292919(17-Cyclopropylmethyl-3,14beta-dihydroxy-4,5r-epoxy...)
Affinity DataEC50:  99nMAssay Description:Agonist activity at mouse DOR expressed in CHO cells after 1.5 hrs by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50066348(CHEMBL3401554)
Affinity DataEC50:  108nMAssay Description:Agonist activity at mouse DOR expressed in CHO cells after 1.5 hrs by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM21008((4S,7S,13S)-13-[(2S)-2-amino-3-(4-hydroxyphenyl)pr...)
Affinity DataEC50:  126nMAssay Description:Agonist activity at DOR in CD1 mouse vas deferens assessed as inhibition of EFS-induced contractions incubated for 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50182946(4-((S)-2-amino-3-oxo-3-((S)-2-(4-phenyl-1H-imidazo...)
Affinity DataEC50:  135nMAssay Description:Activity against delta opioid receptor by stimulation of [35S]GTPgammaS binding in CHO-hgamma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50562077(CHEMBL4754992)
Affinity DataEC50:  140nMAssay Description:Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electric-field induced measured after 5 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50038422((4S,7S,13S)-13-[(2S,3S)-2-Amino-3-(4-hydroxy-2,6-d...)
Affinity DataEC50:  168nMAssay Description:Effective concentration was measured towards delta opioid receptor using mouse vas deferens(MVD, delta) bioassay in vitroMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50133264(CHEMBL133719 | [(2S,3S)-TMT1]DPDPE)
Affinity DataEC50:  170nMAssay Description:In vitro bioassay data to determine the effective concentration required for antagonistic activity against Opioid receptor delta 1 in functional assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50068136(3-[(4-Benzyl-piperazin-1-yl)-phenyl-methyl]-phenol...)
Affinity DataEC50:  174nMAssay Description:Tested for electrically induced smooth muscle contractions from mouse vas deferens expressed in delta opioid receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50068132(3-[(4-Benzyl-piperazin-1-yl)-(4-tert-butyl-phenyl)...)
Affinity DataEC50:  210nMAssay Description:Tested for electrically induced smooth muscle contractions from mouse vas deferens expressed in delta opioid receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50068132(3-[(4-Benzyl-piperazin-1-yl)-(4-tert-butyl-phenyl)...)
Affinity DataEC50:  210nMAssay Description:Tested for electrically induced smooth muscle contractions from mouse vas deferens expressed in delta opioid receptorsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50026763(CHEMBL3331511)
Affinity DataEC50:  360nMAssay Description:Agonist activity at mouse delta opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Catania

Curated by ChEMBL
LigandPNGBDBM50154041((S)-2-amino-3-(4-hydroxyphenyl)-1-((S)-2-(5-methyl...)
Affinity DataEC50:  500nMAssay Description:Activity against delta opioid receptor by stimulation of [35S]GTPgammaS binding in CHO-hgamma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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