Compile Data Set for Download or QSAR
maximum 50k data
Found 258 of ic50 for UniProtKB: P02550
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50070103((E)-1-(2',5'-Dimethoxyphenyl)-3-(4''-N,N-Dimethyla...)
Affinity DataIC50:  12nMAssay Description:Tested for inhibition of polymerization of tubulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50112256(3,4,5-Trimethoxy-benzaldehyde O-(8-hydroxy-5-methy...)
Affinity DataIC50:  170nMAssay Description:Ability to inhibit the GTP/glutamate-induced polymerization of tubulinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50139772(22-oxovincaleukoblastine | leurocristine | vincris...)
Affinity DataIC50:  220nMAssay Description:The compound was evaluated in vitro for the mammalian brain tubulin polymerization using standard assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50280140(CHEMBL418565 | [6-(3,4,5-Trimethoxy-benzyloxy)-imi...)
Affinity DataIC50:  310nMAssay Description:In vitro mammalian brain tubulin polymerization using standard assay.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50037463(2-(3-Methoxy-phenyl)-6-morpholin-4-yl-1H-quinolin-...)
Affinity DataIC50:  363nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50037454(6-(3-Chloro-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin...)
Affinity DataIC50:  372nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50037448(6-Dimethylamino-2-(3-methoxy-phenyl)-1H-quinolin-4...)
Affinity DataIC50:  380nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50037450(2-(3-Methoxy-phenyl)-6-pyrrolidin-1-yl-1H-quinolin...)
Affinity DataIC50:  437nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50409014(CHEMBL50139)
Affinity DataIC50:  447nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50106309(2-(2'-fluorophenyl)-6-pyrolinyl-4-(1H)-quinolone |...)
Affinity DataIC50:  457nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50035218(CHEMBL61 | PODOFILOX | Podophyllinic acid lactone ...)
Affinity DataIC50:  460nMAssay Description:Inhibition of tubulin polymerization.(ITP)More data for this Ligand-Target Pair
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50037462(6-(3-Hydroxy-phenyl)-5H-[1,3]dioxolo[4,5-g]quinoli...)
Affinity DataIC50:  468nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50070107((E)-3-(3''-Hydroxy-4''-methoxyphenyl)-2-methyl-1-(...)
Affinity DataIC50:  500nMAssay Description:Concentration that cause a 50% inhibition in tubulin assembly as measured by an increase inturbidity using microtubule assembly assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50037457(6-(3-Fluoro-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin...)
Affinity DataIC50:  525nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50059968(2-(3-Fluoro-phenyl)-7-methyl-1H-[1,8]naphthyridin-...)
Affinity DataIC50:  525nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  530nMAssay Description:Inhibition of tubulin polymerization(ITP)More data for this Ligand-Target Pair
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50059964(6-Methyl-2-naphthalen-1-yl-1H-[1,8]naphthyridin-4-...)
Affinity DataIC50:  550nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50056948(CHEMBL49847 | Isonicotinic acid (S)-1,2,3-trimetho...)
Affinity DataIC50:  562nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50037444(6-(3-Methoxy-phenyl)-5H-[1,3]dioxolo[4,5-g]quinoli...)
Affinity DataIC50:  575nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A/beta chain(Sus scrofa (Pig))
The University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50095321(2-Methoxy-5-(3,4,5-trimethoxy-benzyloxy)-benzaldeh...)
Affinity DataIC50:  600nMAssay Description:Effect on tubulin binding and the concentration required to cause 50% decrease in tubulin assembly at 350 nm.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50409024(CHEMBL48525)
Affinity DataIC50:  617nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50059971(2-(3-Fluoro-phenyl)-6-methyl-1H-[1,8]naphthyridin-...)
Affinity DataIC50:  631nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding siteMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50009568((Thiocolchicine)N-(1,2,3-Trimethoxy-10-methylsulfa...)
Affinity DataIC50:  646nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50037459(6-(3-Methylamino-phenyl)-5H-[1,3]dioxolo[4,5-g]qui...)
Affinity DataIC50:  646nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50059966(7-Methyl-2-naphthalen-1-yl-1H-[1,8]naphthyridin-4-...)
Affinity DataIC50:  661nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50041119(2-(2-fluorophenyl)-6,7-methylenedioxyquinolin-4-on...)
Affinity DataIC50:  680nMAssay Description:Inhibition of tubulin polymerization(ITP)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50063845((S)-6-(3-Methoxy-phenyl)-6,7-dihydro-5H-[1,3]dioxo...)
Affinity DataIC50:  692nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50409011(CHEMBL45711)
Affinity DataIC50:  724nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50037453(6-(3-Amino-phenyl)-5H-[1,3]dioxolo[4,5-g]quinolin-...)
Affinity DataIC50:  724nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50059961(2-(3-Chloro-phenyl)-6-methyl-1H-[1,8]naphthyridin-...)
Affinity DataIC50:  724nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50059975(2-(3-Fluoro-phenyl)-5,7-dimethyl-1H-[1,8]naphthyri...)
Affinity DataIC50:  741nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50059117(2-(3-Methoxy-phenyl)-7-methyl-1H-[1,8]naphthyridin...)
Affinity DataIC50:  759nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50056949(CHEMBL49518 | Nicotinic acid (S)-1,2,3-trimethoxy-...)
Affinity DataIC50:  759nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50059976(2-(3-Chloro-phenyl)-5,7-dimethyl-1H-[1,8]naphthyri...)
Affinity DataIC50:  776nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50059978(5,7-Dimethyl-2-naphthalen-1-yl-1H-[1,8]naphthyridi...)
Affinity DataIC50:  776nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50059111(2-(3-Methoxy-phenyl)-6-methyl-1H-[1,8]naphthyridin...)
Affinity DataIC50:  794nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50014846((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of tubulin polymerization(ITP)More data for this Ligand-Target Pair
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50037447(6-(3-Trifluoromethyl-phenyl)-5H-[1,3]dioxolo[4,5-g...)
Affinity DataIC50:  813nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50090045((2,3-Dihydroxy-4-methoxy-phenyl)-(3,4,5-trimethoxy...)
Affinity DataIC50:  820nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50020475(CHEMBL341192 | [7-Methyl-5-(thiophene-2-carbonyl)-...)
Affinity DataIC50:  860nMAssay Description:Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50059103(2-(3-Methoxy-phenyl)-5,7-dimethyl-1H-[1,8]naphthyr...)
Affinity DataIC50:  871nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50020464(CHEMBL135161 | [5-(2-Methoxycarbonylamino-1H-benzo...)
Affinity DataIC50:  880nMAssay Description:Displacement of 5.8 uM [3H]-oncodazole from homogeneous tubulin.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50059960(2-(3-Chloro-phenyl)-7-methyl-1H-[1,8]naphthyridin-...)
Affinity DataIC50:  891nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50059972(5-Methyl-2-naphthalen-1-yl-1H-[1,8]naphthyridin-4-...)
Affinity DataIC50:  933nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50059122(2-(3-Methoxy-phenyl)-1H-[1,8]naphthyridin-4-one | ...)
Affinity DataIC50:  955nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50409007(CHEMBL49419)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50103820(CHEMBL309058 | [2-(3-Hydroxy-4-methoxy-phenyl)-thi...)
Affinity DataIC50:  1.00E+3nMAssay Description:Compound was evaluated for inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50005480((-)-combretastatin | (Z)-3'-hydroxy-3,4,4',5-tetra...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50059969(2-Naphthalen-1-yl-1H-[1,8]naphthyridin-4-one | CHE...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of tubulin polymerization interacting at the colchicine binding site.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTubulin alpha-1A chain(Sus scrofa (Pig))
University Of Manchester Institute Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50090044((Z)-2',3'-dihydroxy-3,4,4',5-tetramethoxystilbene ...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of tubulin polymerizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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