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Found 587 of ic50 for UniProtKB: P04054
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053109(CHEMBL331755 | [1-Aminooxalyl-3-(2-benzyl-benzyl)-...)
Affinity DataIC50:  1.30nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053136((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-methyl-indo...)
Affinity DataIC50:  1.40nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053106(CHEMBL120112 | [1-Aminooxalyl-2-ethyl-3-(3-trifluo...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053108((1-Aminooxalyl-3-benzyl-2-methyl-indolizin-8-yloxy...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053102(CHEMBL121245 | [1-Aminooxalyl-3-(3-chloro-benzyl)-...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053137((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-ethyl-indol...)
Affinity DataIC50:  3nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053114((1-Aminooxalyl-3-biphenyl-3-ylmethyl-2-ethyl-indol...)
Affinity DataIC50:  4.20nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053123((1-Aminooxalyl-2-ethyl-3-naphthalen-1-ylmethyl-ind...)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053096(CHEMBL123774 | [1-Aminooxalyl-3-(4-butyl-benzyl)-2...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053133((1-Aminooxalyl-3-benzyl-2-ethyl-indolizin-8-yloxy)...)
Affinity DataIC50:  5nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053137((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-ethyl-indol...)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053147((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-cyclopropyl...)
Affinity DataIC50:  6nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053109(CHEMBL331755 | [1-Aminooxalyl-3-(2-benzyl-benzyl)-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053102(CHEMBL121245 | [1-Aminooxalyl-3-(3-chloro-benzyl)-...)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053095((1-Aminooxalyl-2-ethyl-3-naphthalen-2-ylmethyl-ind...)
Affinity DataIC50:  7.30nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053108((1-Aminooxalyl-3-benzyl-2-methyl-indolizin-8-yloxy...)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053133((1-Aminooxalyl-3-benzyl-2-ethyl-indolizin-8-yloxy)...)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053136((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-methyl-indo...)
Affinity DataIC50:  8nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053106(CHEMBL120112 | [1-Aminooxalyl-2-ethyl-3-(3-trifluo...)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053114((1-Aminooxalyl-3-biphenyl-3-ylmethyl-2-ethyl-indol...)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053147((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-cyclopropyl...)
Affinity DataIC50:  9nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053140((1-Aminooxalyl-3-[2,2']bithiophenyl-4-ylmethyl-2-e...)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053116((1-Aminooxalyl-3-cyclohexylmethyl-2-methyl-indoliz...)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053140((1-Aminooxalyl-3-[2,2']bithiophenyl-4-ylmethyl-2-e...)
Affinity DataIC50:  11nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053096(CHEMBL123774 | [1-Aminooxalyl-3-(4-butyl-benzyl)-2...)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053112((1-Aminooxalyl-2-ethyl-3-thiophen-2-ylmethyl-indol...)
Affinity DataIC50:  11nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053155((1-Aminooxalyl-3-biphenyl-4-ylmethyl-2-ethyl-indol...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053112((1-Aminooxalyl-2-ethyl-3-thiophen-2-ylmethyl-indol...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053139((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-methoxy-ind...)
Affinity DataIC50:  13nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053113((3-Biphenyl-2-ylmethyl-1-carbamoylmethyl-2-cyclopr...)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053104((3-Benzyl-1-carbamoylmethyl-2-ethyl-indolizin-8-yl...)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053125((3-Biphenyl-2-ylmethyl-1-carbamoylmethyl-2-ethyl-i...)
Affinity DataIC50:  14nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053141((1-Aminooxalyl-3-cyclopentylmethyl-2-methyl-indoli...)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053125((3-Biphenyl-2-ylmethyl-1-carbamoylmethyl-2-ethyl-i...)
Affinity DataIC50:  14nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053139((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-methoxy-ind...)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053116((1-Aminooxalyl-3-cyclohexylmethyl-2-methyl-indoliz...)
Affinity DataIC50:  15nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053154(CHEMBL121199 | [1-Carbamoylmethyl-3-(3-chloro-benz...)
Affinity DataIC50:  15nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053110((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-methylsulfa...)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053120((1-Aminooxalyl-3-biphenyl-2-ylmethyl-2-ethyl-indol...)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053095((1-Aminooxalyl-2-ethyl-3-naphthalen-2-ylmethyl-ind...)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053143(CHEMBL123394 | [1-Aminooxalyl-2-ethyl-3-(2-methyl-...)
Affinity DataIC50:  17nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053155((1-Aminooxalyl-3-biphenyl-4-ylmethyl-2-ethyl-indol...)
Affinity DataIC50:  18nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM82341(hnpsPLA2-IIa Inhibitor, 2l)
Affinity DataIC50:  19nMAssay Description:Compounds 2a-q were evaluated as inhibitors by using an in vitro colorimetric enzyme assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053132((1-Aminooxalyl-3-cyclopentylmethyl-2-ethyl-indoliz...)
Affinity DataIC50:  19nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053132((1-Aminooxalyl-3-cyclopentylmethyl-2-ethyl-indoliz...)
Affinity DataIC50:  19nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053146(CHEMBL331184 | [1-Aminooxalyl-2-ethyl-3-((S)-3-pen...)
Affinity DataIC50:  20nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053153(CHEMBL120553 | [1-Aminooxalyl-2-ethyl-3-(3-methoxy...)
Affinity DataIC50:  21nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053098((1-Aminooxalyl-3-cyclohexylmethyl-2-ethyl-indolizi...)
Affinity DataIC50:  21nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053141((1-Aminooxalyl-3-cyclopentylmethyl-2-methyl-indoli...)
Affinity DataIC50:  22nMAssay Description:Inhibitory activity against recombinant human secretory phospholipase A2 (s-PLA2) by phosphatidylcholine/deoxycholate assay (PC/DOC).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2(Homo sapiens (Human))
Shionogi

Curated by ChEMBL
LigandPNGBDBM50053165((1-Aminooxalyl-2-cyclopropyl-3-naphthalen-1-ylmeth...)
Affinity DataIC50:  23nMAssay Description:Inhibition of recombinant human secretory phospholipase A2 (sPLA2), chromogenic screening assay.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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