Compile Data Set for Download or QSAR
maximum 50k data
Found 263 of ic50 for UniProtKB: P10586
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296375((3S)-6-[4-(2,2-Dimethyl-1,3-dithiolan-4-yl)butylca...)
Affinity DataIC50:  380nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296376((3S)-7-[4-(2,2-Dimethyl-1,3-dithiolan-4-yl)butylca...)
Affinity DataIC50:  382nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326165(CHEMBL1241315 | oxalylaminobenzoic acid)
Affinity DataIC50:  410nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50079855((R)-2-[2,6-Dibromo-4-(6-bromo-benzo[b]naphtho[2,3-...)
Affinity DataIC50:  420nMAssay Description:The compound was tested in vitro for the inhibitory activity against LAR (human Protein-tyrosine phosphatase F)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296374((3S)-7-[2-(2,2-Dimethyl-1,3-dithiolan-4-yl)ethylca...)
Affinity DataIC50:  458nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296373((3S)-6-[2-(2,2-Dimethyl-1,3-dithiolan-4-yl)ethylca...)
Affinity DataIC50:  493nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296372((3S)-7-[3-(2-Thienyl)propylcarboxamido]-isochroman...)
Affinity DataIC50:  625nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50177318(2-(4-(7-(4-tetradecylbenzoyl)cyclopenta[d][1,2]oxa...)
Affinity DataIC50:  690nMAssay Description:Inhibitory activity against LAR protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296371((3S)-6-[3-(2-Thienyl)propylcarboxamido]-isochroman...)
Affinity DataIC50:  765nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50262987(CHEMBL506661 | Illudalic acid)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human recombinant LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326151(8-(2-Methylthiazol-4-yl)dibenzo[b,d]furan-4-carbox...)
Affinity DataIC50:  1.32E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50079856(CHEMBL108721 | [2,6-Dibromo-4-(6-bromo-benzo[b]nap...)
Affinity DataIC50:  1.50E+3nMAssay Description:The compound was tested in vitro for the inhibitory activity against LAR (human Protein-tyrosine phosphatase F)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50263036(3-Hydroxy-6-methoxy-8,8-dimethyl-1-oxo-1,3,4,7,8,9...)
Affinity DataIC50:  1.53E+3nMAssay Description:Inhibition of human recombinant LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296382((3S)-7-{4-[(3R)-1,2-Dithiolan-3-yl]butylcarboxamid...)
Affinity DataIC50:  1.94E+3nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326163((E)-8-{2-[4-(2-Carboxyvinyl)phenyl]thiazol-4-yl}di...)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326164((E)-8-{2-[3-(2-Carboxyvinyl)phenyl]thiazol-4-yl}di...)
Affinity DataIC50:  2.07E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326156(8-{2-[4-(Piperidin-1-yl)phenyl]thiazol-4-yl}dibenz...)
Affinity DataIC50:  2.07E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50262987(CHEMBL506661 | Illudalic acid)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of LAR (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50262987(CHEMBL506661 | Illudalic acid)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of LAR (unknown origin) using DiFMUP as substrate incubated for 30 mins followed by substrate addition at pH 6.5 by standard phosphatase a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326162(8-[2-(3-Iodophenyl)thiazol-4-yl]dibenzo[b,d]furan-...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326158(8-{2-[4-(2,6-Dimethylmorpholino)phenyl]thiazol-4-y...)
Affinity DataIC50:  2.14E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296380((3S)-7-[4-(1,2-Dithiolan-3-yl)butylcarboxamido]-is...)
Affinity DataIC50:  2.38E+3nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296381((3S)-6-{4-[(3R)-1,2-Dithiolan-3-yl]butylcarboxamid...)
Affinity DataIC50:  2.39E+3nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50099778(4-Phenyl-[1,2]naphthoquinone | CHEMBL51447)
Affinity DataIC50:  2.49E+3nMAssay Description:In vitro inhibitory activity of the compound against recombinant human LAR using fluoreacein diphosphate (FDP) as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326161(8-[2-(4-Iodophenyl)thiazol-4-yl]dibenzo[b,d]furan-...)
Affinity DataIC50:  2.65E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326153(8-[2-(4-Aminophenyl)thiazol-4-yl]dibenzo[b,d]furan...)
Affinity DataIC50:  2.69E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296379((3S)-6-[4-(1,2-Dithiolan-3-yl)butylcarboxamido]-is...)
Affinity DataIC50:  2.85E+3nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326152(8-[2-(4-Nitrophenyl)thiazol-4-yl]dibenzo[b,d]furan...)
Affinity DataIC50:  2.87E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326157(8-[2-(4-Morpholinophenyl)thiazol-4-yl]dibenzo[b,d]...)
Affinity DataIC50:  2.94E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326155(8-{2-[4-(Pyrrolidin-1-yl)phenyl]thiazol-4-yl}diben...)
Affinity DataIC50:  2.99E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326159(8-[2-(4-Carboxyphenyl)thiazol-4-yl]dibenzo[b,d]fur...)
Affinity DataIC50:  3.25E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50409191(CHEMBL365490)
Affinity DataIC50:  3.25E+3nMAssay Description:in vitro inhibitory activity against LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296391((2S)-3-(4-{4-[(3R)-1,2-Dithiolan-3-yl]butylcarboxa...)
Affinity DataIC50:  3.29E+3nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326160(8-[2-(3,5-Dibromo-4-(1-carboxy-2-phenylethoxy)phen...)
Affinity DataIC50:  3.57E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50326154(8-{2-[4-(Dimethylamino)phenyl]thiazol-4-yl}dibenzo...)
Affinity DataIC50:  3.75E+3nMAssay Description:Inhibition of human recombinant LAR after 30 mins by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50148911((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of human recombinant LAR expressed in Escherichia coli TB1 using p-nitrophenyl phosphate as substrate after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296385((3S)-6-{4-[(4R)-1,3-Dithian-4-yl]butylcarboxamido}...)
Affinity DataIC50:  4.07E+3nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296386((3S)-7-{4-[(4R)-1,3-Dithian-4-yl]butylcarboxamido}...)
Affinity DataIC50:  4.37E+3nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296390((2S)-3-(4-{4-[(3R)-1,2-Dithiolan-3-yl]butylcarboxa...)
Affinity DataIC50:  4.66E+3nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296377((3S)-6-[2-(2,2-Diphenyl-1,3-dithiolan-4-yl)ethylca...)
Affinity DataIC50:  4.98E+3nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296378((3S)-7-[2-(2,2-Diphenyl-1,3-dithiolan-4-yl)ethylca...)
Affinity DataIC50:  5.06E+3nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50290909(CHEMBL4164960)
Affinity DataIC50:  5.36E+3nMAssay Description:Inhibition of human GST-tagged LAR D1 (1275 to 1613 residues) expressed in Escherichia coli BL21-CondenPlus (DE3) using pNNP as substrateMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296389((3S)-7-{4-[(3R)-1,2-Dithiolan-3-yl]butylcarboxamid...)
Affinity DataIC50:  5.86E+3nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296393((2S)-2-Butoxy-3-(4-{4-[(3R)-1,2-dithiolan-3-yl]but...)
Affinity DataIC50:  5.86E+3nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296370((3S)-7-[4-(2-Thienyl)butylcarboxamido]-isochroman-...)
Affinity DataIC50:  5.91E+3nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296392((2S)-3-(4-{4-[(3R)-1,2-Dithiolan-3-yl]butylcarboxa...)
Affinity DataIC50:  5.98E+3nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296384((3S)-7-{4-[(4S)-2-Oxoperhydrothieno-[3,4-d]imidazo...)
Affinity DataIC50:  6.47E+3nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50282483(CHEMBL4161709)
Affinity DataIC50:  6.95E+3nMAssay Description:Inhibition of human GST-tagged LAR D1 (1275 to 1613 residues) expressed in Escherichia coli BL21-CondenPlus (DE3) using pNNP as substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296388((3S)-7-{4-[(4R)-2,2-Diphenyl-1,3-dithian-4-yl]buty...)
Affinity DataIC50:  7.03E+3nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein phosphatase F(Homo sapiens (Human))
Glenmark Research Center

Curated by ChEMBL
LigandPNGBDBM50296369((3S)-6-[4-(2-Thienyl)-butylcarboxamido]-isochroman...)
Affinity DataIC50:  7.03E+3nMAssay Description:Inhibition of LARMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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