BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 8 hits of ic50 data for polymerid = 4999   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin N-acetyltransferase (AANAT)


(Homo sapiens (Human))
BDBM85592
PNG
(AANAT Inhibitor, 12d)
Show SMILES Oc1ccc2scc(CCNC(=O)CBr)c2c1
Show InChI InChI=1S/C12H12BrNO2S/c13-6-12(16)14-4-3-8-7-17-11-2-1-9(15)5-10(8)11/h1-2,5,7,15H,3-4,6H2,(H,14,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 180n/an/an/an/a6.837



Université de Lille



Assay Description
The compounds were evaluated in a human serotonin N-acetyltransferase assay.


J Enzyme Inhib Med Chem 17: 409-14 (2002)

More data for this
Ligand-Target Pair
Serotonin N-acetyltransferase (AANAT)


(Homo sapiens (Human))
BDBM85590
PNG
(AANAT Inhibitor, 8h)
Show SMILES Fc1ccc2scc(CCNC(=O)CBr)c2c1
Show InChI InChI=1S/C12H11BrFNOS/c13-6-12(16)15-4-3-8-7-17-11-2-1-9(14)5-10(8)11/h1-2,5,7H,3-4,6H2,(H,15,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 390n/an/an/an/a6.837



Université de Lille



Assay Description
The compounds were evaluated in a human serotonin N-acetyltransferase assay.


J Enzyme Inhib Med Chem 17: 409-14 (2002)

More data for this
Ligand-Target Pair
Serotonin N-acetyltransferase (AANAT)


(Homo sapiens (Human))
BDBM85587
PNG
(AANAT Inhibitor, 8d)
Show SMILES COc1ccc2scc(CCNC(=O)CBr)c2c1
Show InChI InChI=1S/C13H14BrNO2S/c1-17-10-2-3-12-11(6-10)9(8-18-12)4-5-15-13(16)7-14/h2-3,6,8H,4-5,7H2,1H3,(H,15,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 610n/an/an/an/a6.837



Université de Lille



Assay Description
The compounds were evaluated in a human serotonin N-acetyltransferase assay.


J Enzyme Inhib Med Chem 17: 409-14 (2002)

More data for this
Ligand-Target Pair
Serotonin N-acetyltransferase (AANAT)


(Homo sapiens (Human))
BDBM85588
PNG
(AANAT Inhibitor, 8e)
Show SMILES BrCC(=O)NCCc1csc2ccccc12
Show InChI InChI=1S/C12H12BrNOS/c13-7-12(15)14-6-5-9-8-16-11-4-2-1-3-10(9)11/h1-4,8H,5-7H2,(H,14,15)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 680n/an/an/an/a6.837



Université de Lille



Assay Description
The compounds were evaluated in a human serotonin N-acetyltransferase assay.


J Enzyme Inhib Med Chem 17: 409-14 (2002)

More data for this
Ligand-Target Pair
Serotonin N-acetyltransferase (AANAT)


(Homo sapiens (Human))
BDBM85591
PNG
(AANAT Inhibitor, 8i)
Show SMILES CCc1ccc2scc(CCNC(=O)CBr)c2c1
Show InChI InChI=1S/C14H16BrNOS/c1-2-10-3-4-13-12(7-10)11(9-18-13)5-6-16-14(17)8-15/h3-4,7,9H,2,5-6,8H2,1H3,(H,16,17)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 700n/an/an/an/a6.837



Université de Lille



Assay Description
The compounds were evaluated in a human serotonin N-acetyltransferase assay.


J Enzyme Inhib Med Chem 17: 409-14 (2002)

More data for this
Ligand-Target Pair
Serotonin N-acetyltransferase (AANAT)


(Homo sapiens (Human))
BDBM50282747
PNG
(2-Bromo-N-[2-(1H-indol-3-yl)-ethyl]-acetamide | AA...)
Show SMILES BrCC(=O)NCCc1c[nH]c2ccccc12
Show InChI InChI=1S/C12H13BrN2O/c13-7-12(16)14-6-5-9-8-15-11-4-2-1-3-10(9)11/h1-4,8,15H,5-7H2,(H,14,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.43E+3n/an/an/an/a6.837



Université de Lille



Assay Description
The compounds were evaluated in a human serotonin N-acetyltransferase assay.


J Enzyme Inhib Med Chem 17: 409-14 (2002)

More data for this
Ligand-Target Pair
Serotonin N-acetyltransferase (AANAT)


(Homo sapiens (Human))
BDBM85589
PNG
(AANAT Inhibitor, 8g)
Show SMILES BrCC(=O)NCCc1csc2ccc(Br)cc12
Show InChI InChI=1S/C12H11Br2NOS/c13-6-12(16)15-4-3-8-7-17-11-2-1-9(14)5-10(8)11/h1-2,5,7H,3-4,6H2,(H,15,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 3.78E+3n/an/an/an/a6.837



Université de Lille



Assay Description
The compounds were evaluated in a human serotonin N-acetyltransferase assay.


J Enzyme Inhib Med Chem 17: 409-14 (2002)

More data for this
Ligand-Target Pair
Serotonin N-acetyltransferase (AANAT)


(Homo sapiens (Human))
BDBM85586
PNG
(AANAT Inhibitor, 8c)
Show SMILES COc1ccc2occ(CCNC(=O)CBr)c2c1
Show InChI InChI=1S/C13H14BrNO3/c1-17-10-2-3-12-11(6-10)9(8-18-12)4-5-15-13(16)7-14/h2-3,6,8H,4-5,7H2,1H3,(H,15,16)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 4.00E+4n/an/an/an/a6.837



Université de Lille



Assay Description
The compounds were evaluated in a human serotonin N-acetyltransferase assay.


J Enzyme Inhib Med Chem 17: 409-14 (2002)

More data for this
Ligand-Target Pair