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Compile Data Set for Download or QSAR

Found 458 hits Enz. Inhib. hit(s) with BLAST sequence identity > 85%    Zinc 0: unavailable per Zinc DB. Zinc 1: purchasable, 2 weeks to supply. Zinc 2: made on demand. Zinc 4: potentially available
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Retinoic acid receptor alpha


(Homo sapiens)
[3H]Retinoic acid
PNG
([3H]RA | [3H]Vitamin A acid | [3H]tretinoin)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
PDB
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PDB
0.1n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity towards human Retinoic acid receptor alpha


Bioorg Med Chem Lett 7: 2313-2318 (1997)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL89241
PNG
((2E,4E,6E)-7-(3,5-Di-tert-butyl-phenyl)-3-methyl-o...)
Show SMILES C\C(\C=C\C=C(/C)c1cc(cc(c1)C(C)(C)C)C(C)(C)C)=C/C(O)=O
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1.1n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR alpha


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL74331
PNG
((2E,4E)-3-Methyl-5-{2-[(E)-2-(3,3,6,6-tetramethyl-...)
Show SMILES C\C(\C=C\C1CC1\C=C\C1=CC(C)(C)CCC1(C)C)=C/C(O)=O
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3.1n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Binding affinity towards human Retinoic acid receptor alpha


Bioorg Med Chem Lett 7: 2313-2318 (1997)

More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
AT-RA
PNG
(CHEMBL38 | Vitamin A acid | all-trans retinoic aci...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
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Article
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3.3n/an/an/an/an/an/an/an/a



University of Tokyo

Curated by ChEMBL


Assay Description
Agonistic activity of the compound towards retinoic acid receptor-alpha


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL36768
PNG
(4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-anthrace...)
Show SMILES CC1(C)CCC(C)(C)c2cc3cc(ccc3cc12)-c1ccc(cc1)C(O)=O
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5.3n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL25202
PNG
(4-[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthal...)
Show SMILES CC1(C)CCC(C)(C)c2cc(NC(=O)c3ccc(cc3)C(O)=O)ccc12
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6.5n/an/an/an/an/an/an/an/a



University of Tokyo

Curated by ChEMBL


Assay Description
Agonistic activity of the compound towards retinoic acid receptor-alpha


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
[3H]Retinoic acid
PNG
([3H]RA | [3H]Vitamin A acid | [3H]tretinoin)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
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16.0n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligand


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL275311
PNG
((E)-4-(2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydrona...)
Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc2c(c1)C(C)(C)CCC2(C)C
PDB
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21.0n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligand


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Retinoic acid receptor alpha


(Homo sapiens)
9C-RA
PNG
(9-cis retinoic acid | CHEMBL705 | Panretin | alitr...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C\C=C\C(\C)=C\C(O)=O
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22.3n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR alpha


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL42314
PNG
((2E,4E,6Z)-7-[3,5-Di-tert-butyl-2-(2,2-difluoro-et...)
Show SMILES C\C(\C=C\C=C(\C)c1cc(cc(c1OCC(F)F)C(C)(C)C)C(C)(C)C)=C/C(O)=O
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54.0n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against RAR alpha receptor using [3H]-ATRA as radioligand in CV-1 cells


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL89241
PNG
((2E,4E,6E)-7-(3,5-Di-tert-butyl-phenyl)-3-methyl-o...)
Show SMILES C\C(\C=C\C=C(/C)c1cc(cc(c1)C(C)(C)C)C(C)(C)C)=C/C(O)=O
PDB
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63.5n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR alpha


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL62047
PNG
((E)-3-[5-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)-c1ccc(\C=C\C(O)=O)o1
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93.0n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acid


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL74826
PNG
(4-[(E)-2-(3-tert-Butyl-4-methoxy-phenyl)-propenyl]...)
Show SMILES COc1ccc(cc1C(C)(C)C)C(\C)=C\c1ccc(cc1)C(O)=O
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130.0n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
BEXAROTENE
PNG
(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Show SMILES Cc1cc2c(cc1C(=C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C
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180.0n/an/an/an/an/an/an/an/a



University of Tokyo

Curated by ChEMBL


Assay Description
Selective activity of the compound towards retinoic acid receptor-alpha


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
AT-RA
PNG
(CHEMBL38 | Vitamin A acid | all-trans retinoic aci...)
Show SMILES C\C(\C=C\C1=C(C)CCCC1(C)C)=C/C=C/C(/C)=C/C(O)=O
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187.0n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR alpha


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL111589
PNG
((2E,4E,6Z)-7-(3-Methoxy-5,5,8,8-tetramethyl-5,6,7,...)
Show SMILES COc1cc2c(cc1\C(C)=C/C=C/C(/C)=C/C(O)=O)C(C)(C)CCC2(C)C
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306.0n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to Retinoic acid receptor RAR alpha


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL356326
PNG
(4-{(E)-2-[4-Methoxy-3-(1-methyl-cyclohexyl)-phenyl...)
Show SMILES COc1ccc(cc1C1(C)CCCCC1)C(\C)=C\c1ccc(cc1)C(O)=O
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420.0n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL146449
PNG
(4-[(E)-2-(3-Adamantan-1-yl-4-methoxy-phenyl)-prope...)
Show SMILES COc1ccc(cc1C12CC3CC(CC(C3)C1)C2)C(\C)=C\c1ccc(cc1)C(O)=O
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460.0n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL75848
PNG
(3-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthal...)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C1=Cc2ccc(cc2OC1)C(O)=O
PDB
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487.0n/an/an/an/an/an/an/an/a


TBA

Assay Description
Binding affinity towards Retinoic acid receptor alpha


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL25361
PNG
(5',5',8',8'-Tetramethyl-5',6',7',8'-tetrahydro-[2,...)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)-c1ccc2cc(ccc2c1)C(O)=O
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580.0n/an/an/an/an/an/an/an/a


TBA

Assay Description
Binding affinity towards Retinoic acid receptor alpha


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL25361
PNG
(5',5',8',8'-Tetramethyl-5',6',7',8'-tetrahydro-[2,...)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)-c1ccc2cc(ccc2c1)C(O)=O
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580.0n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL146646
PNG
(4-[(E)-2-(3-Adamantan-1-yl-4-hydroxy-phenyl)-vinyl...)
Show SMILES OC(=O)c1ccc(\C=C\c2ccc(O)c(c2)C23CC4CC(CC(C4)C2)C3)cc1
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610.0n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL357917
PNG
(6-[3-Adamantan-1-yl-4-(3-hydroxy-propyl)-phenyl]-n...)
Show SMILES OCCCc1ccc(cc1C12CC3CC(CC(C3)C1)C2)-c1ccc2cc(ccc2c1)C(O)=O
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695.0n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL75732
PNG
(3-(3-Adamantan-1-yl-4-methoxy-phenyl)-2H-chromene-...)
Show SMILES COc1ccc(cc1C12C[C@H]3C[C@H](C[C@H](C3)C1)C2)C1=Cc2ccc(cc2OC1)C(O)=O
PDB
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764.0n/an/an/an/an/an/an/an/a


TBA

Assay Description
Binding affinity towards Retinoic acid receptor alpha


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL75048
PNG
(3-(3-Adamantan-1-yl-4-hydroxy-phenyl)-2H-chromene-...)
Show SMILES OC(=O)c1ccc2C=C(COc2c1)c1ccc(O)c(c1)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2
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821.0n/an/an/an/an/an/an/an/a


TBA

Assay Description
Binding affinity towards Retinoic acid receptor alpha


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL348449
PNG
(4-[(E)-2-(3-tert-Butyl-4-hydroxy-phenyl)-propenyl]...)
Show SMILES C\C(=C/c1ccc(cc1)C(O)=O)c1ccc(O)c(c1)C(C)(C)C
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834.0n/an/an/an/an/an/an/an/a



CIRD GALDERMA

Curated by ChEMBL


Assay Description
Binding affinity to retinoic acid receptor alpha using [3H]-CD 367 as radioligand


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL337859
PNG
(4-(7,7,10,10-Tetramethyl-7,8,9,10-tetrahydro-5-thi...)
Show SMILES CC1(C)CCC(C)(C)c2cc3c(Sc4ccccc4N=C3c3ccc(cc3)C(O)=O)cc12
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900.0n/an/an/an/an/an/an/an/a



University of Tokyo

Curated by ChEMBL


Assay Description
Synergistic activity of the compound towards retinoic acid receptor-alpha


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL96184
PNG
(4-[1-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-napht...)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C(=C)c1ccc(cc1)C(O)=O
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944.0n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to RAR alpha receptor


Bioorg Med Chem Lett 7: 2747-2752 (1997)

More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL334534
PNG
(4-(7,7,10,10-Tetramethyl-7,8,9,10-tetrahydro-5-oxa...)
Show SMILES CC1(C)CCC(C)(C)c2cc3c(Oc4ccccc4N=C3c3ccc(cc3)C(O)=O)cc12
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980.0n/an/an/an/an/an/an/an/a



University of Tokyo

Curated by ChEMBL


Assay Description
Synergistic activity of the compound towards retinoic acid receptor-alpha


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL62537
PNG
((E)-3-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C1CCCc2sc(\C=C\C(O)=O)cc12
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>1000.0n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acid


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL305115
PNG
(5-[1-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-na...)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C1CCCc2oc(\C=C3\SC(=O)NC3=O)cc12
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>1000.0n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acid


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL60089
PNG
(4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-naphthal...)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C1CCCc2oc(cc12)C(O)=O
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>1000.0n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acid


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL64222
PNG
((E)-3-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Show SMILES CC1(C)CCC(C)(C)c2cc(ccc12)C1CCCc2oc(\C=C\C(O)=O)nc12
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>1000.0n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acid


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL63048
PNG
((E)-3-[4-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydro-n...)
Show SMILES CC1(C)CCC(C)(C)c2cc(Cc3coc(\C=C\C(O)=O)c3)ccc12
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>1000.0n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acid


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL432140
PNG
((E)-3-[4-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro...)
Show SMILES Cc1cc2c(cc1C1CCCc3oc(\C=C\C(O)=O)cc13)C(C)(C)CCC2(C)C
PDB
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>1000.0n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Binding affinity for retinoic acid receptor alpha (RARalpha), using 9-cis-[3H]-retinoic acid


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL42314
PNG
((2E,4E,6Z)-7-[3,5-Di-tert-butyl-2-(2,2-difluoro-et...)
Show SMILES C\C(\C=C\C=C(\C)c1cc(cc(c1OCC(F)F)C(C)(C)C)C(C)(C)C)=C/C(O)=O
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>1000.0n/an/an/an/an/an/an/an/a



Ligand Pharmaceuticals Inc

Curated by ChEMBL


Assay Description
Binding affinity against retinoic acid receptor alpha by [3H]-ATRA displacement.


Citation and Details
More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
BEXAROTENE
PNG
(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Show SMILES Cc1cc2c(cc1C(=C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C
PDB
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>1000.0n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to RAR alpha receptor


Bioorg Med Chem Lett 7: 2747-2752 (1997)

More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL93518
PNG
((2E,4E)-3-Methyl-5-[1-(5,5,8,8-tetramethyl-5,6,7,8...)
Show SMILES C\C(\C=C\C1(CC1)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
PDB
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>1000.0n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to RAR alpha receptor


Bioorg Med Chem Lett 7: 2747-2752 (1997)

More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL92394
PNG
((2E,4E)-3-Methyl-5-[1-(3,5,5,8,8-pentamethyl-5,6,7...)
Show SMILES C\C(\C=C\C1(CCCC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O
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>1000.0n/an/an/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to RAR alpha receptor


Bioorg Med Chem Lett 7: 2747-2752 (1997)

More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL93848
PNG
((2E,4E)-3-Methyl-5-[1-(5,5,8,8-tetramethyl-5,6,7,8...)
Show SMILES C\C(\C=C\C1(CCCC1)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
PDB
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TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to RAR alpha receptor


Bioorg Med Chem Lett 7: 2747-2752 (1997)

More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL92284
PNG
((2E,4E)-3-Methyl-5-[1-(3,5,5,8,8-pentamethyl-5,6,7...)
Show SMILES C\C(\C=C\C1(CC1)c1cc2c(cc1C)C(C)(C)CCC2(C)C)=C/C(O)=O
PDB
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TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to RAR alpha receptor


Bioorg Med Chem Lett 7: 2747-2752 (1997)

More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL75814
PNG
((2E,4E)-3-Methyl-5-[(1S,2R)-1-methyl-2-(5,5,8,8-te...)
Show SMILES C\C(\C=C\[C@]1(C)CCC[C@@H]1c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
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TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to retinoic acid receptor RAR alpha


Bioorg Med Chem Lett 7: 2393-2398 (1997)

More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL80424
PNG
((2E,4E)-3-Methyl-5-[(1S,2S)-4-methylene-2-(5,5,8,8...)
Show SMILES C\C(\C=C\[C@@H]1CC(=C)C[C@@H]1c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
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TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to retinoic acid receptor RAR alpha


Bioorg Med Chem Lett 7: 2393-2398 (1997)

More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL79234
PNG
(3-Methyl-5-[2-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Show SMILES C\C(\C=C\C1=C(CCC1)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
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TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to retinoic acid receptor RAR alpha


Bioorg Med Chem Lett 7: 2393-2398 (1997)

More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL311113
PNG
((2E,4E)-3-Methyl-5-[(1S,2S)-2-(5,5,8,8-tetramethyl...)
Show SMILES C\C(\C=C\[C@@H]1CCC[C@@H]1c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
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TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to retinoic acid receptor RAR alpha


Bioorg Med Chem Lett 7: 2393-2398 (1997)

More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL312395
PNG
((2E,4E)-3-Methyl-5-[(1R,2R)-1-methyl-2-(5,5,8,8-te...)
Show SMILES C\C(\C=C\[C@@]1(C)CCC[C@@H]1c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
PDB
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TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to retinoic acid receptor RAR alpha


Bioorg Med Chem Lett 7: 2393-2398 (1997)

More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
BEXAROTENE
PNG
(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Show SMILES Cc1cc2c(cc1C(=C)c1ccc(cc1)C(O)=O)C(C)(C)CCC2(C)C
PDB
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TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to retinoic acid receptor RAR alpha


Bioorg Med Chem Lett 7: 2393-2398 (1997)

More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL80236
PNG
((2E,4E)-3-Methyl-5-[(1R,2S)-2-(5,5,8,8-tetramethyl...)
Show SMILES C\C(\C=C\[C@H]1CCC[C@@H]1c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
PDB
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TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to retinoic acid receptor RAR alpha


Bioorg Med Chem Lett 7: 2393-2398 (1997)

More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL310047
PNG
(3-Methyl-5-[5-(5,5,8,8-tetramethyl-5,6,7,8-tetrahy...)
Show SMILES C\C(\C=C\[C@]12CC1(CCC2)c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
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TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to retinoic acid receptor RAR alpha


Bioorg Med Chem Lett 7: 2393-2398 (1997)

More data for this
Ligand-Target Pair
Retinoic acid receptor alpha


(Homo sapiens)
CHEMBL312233
PNG
((2E,4E)-3-Methyl-5-[(1R,2S)-4-methylene-2-(5,5,8,8...)
Show SMILES C\C(\C=C\[C@H]1CC(=C)C[C@@H]1c1ccc2c(c1)C(C)(C)CCC2(C)C)=C/C(O)=O
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TBA

Curated by ChEMBL


Assay Description
Inhibition of [3H]-ATRA binding to retinoic acid receptor RAR alpha


Bioorg Med Chem Lett 7: 2393-2398 (1997)

More data for this
Ligand-Target Pair
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