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Compile Data Set for Download or QSAR

Found 1461 hits of affinity data for UniProtKB/TrEMBL: P21397    Zinc 0: unavailable per Zinc DB. Zinc 1: purchasable, 2 weeks to supply. Zinc 2: made on demand. Zinc 4: potentially available
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL293004
PNG
(1-[3-(4-Hydroxy-phenyl)-5-(2-methoxy-phenyl)-4,5-d...)
Show SMILES COc1ccccc1C1CC(=NN1C(C)=O)c1ccc(O)cc1
PDB
MMDB

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ZINC 0

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Article
PubMed
2.0n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Roma La Sapienza

Curated by ChEMBL


Assay Description
Binding affinity was evaluated against human monoamino oxidase A


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1645547
PNG
(7-(4,4,4-Trifluorobutoxy)-1-methyl-beta-carboline)
Show SMILES Cc1nccc2c3ccc(OCCCC(F)(F)F)cc3[nH]c12
PDB
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3.6n/an/an/an/an/an/an/an/a



Facult£s Universitaires Notre-Dame de la Paix

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1645545
PNG
(7-(Isobutyloxy)-1-methyl-beta-carboline)
Show SMILES CC(C)COc1ccc2c(c1)[nH]c1c(C)nccc21
PDB
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3.9n/an/an/an/an/an/an/an/a



Facult£s Universitaires Notre-Dame de la Paix

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL303112
PNG
(1-[3-(2,4-Dihydroxy-phenyl)-5-(2-methoxy-phenyl)-4...)
Show SMILES COc1ccccc1C1CC(=NN1C(C)=O)c1ccc(O)cc1O
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4.0n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Roma La Sapienza

Curated by ChEMBL


Assay Description
Binding affinity was evaluated against human monoamino oxidase A


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1645548
PNG
(7-(Cyclohexylmethoxy)-1-methyl-beta-carboline)
Show SMILES Cc1nccc2c3ccc(OCC4CCCCC4)cc3[nH]c12
PDB
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4.3n/an/an/an/an/an/an/an/a



Facult£s Universitaires Notre-Dame de la Paix

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1645550
PNG
(7-(Phenethoxy)-1-methyl-beta-carboline)
Show SMILES Cc1nccc2c3ccc(OCCc4ccccc4)cc3[nH]c12
PDB
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5.0n/an/an/an/an/an/an/an/a



Facult£s Universitaires Notre-Dame de la Paix

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1645544
PNG
(7-(Allyloxy)-1-methyl-beta-carboline)
Show SMILES Cc1nccc2c3ccc(OCC=C)cc3[nH]c12
PDB
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5.0n/an/an/an/an/an/an/an/a



Facult£s Universitaires Notre-Dame de la Paix

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
Moclobemide
PNG
(4-chloro-N-(2-morpholin-4-ylethyl)benzamide | 4-c...)
Show SMILES Clc1ccc(cc1)C(=O)NCCN1CCOCC1
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5.0n/an/an/an/an/an/an/an/a



Birla Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of human MAO-A expressed in BTI insect cells using p-tyramine as substrate after 60 mins


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
HARMINE
PNG
(11h | 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE | 7-Met...)
Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21
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5.0n/an/an/an/an/an/an/an/a



University of Cambridge

Curated by ChEMBL


Assay Description
Inhibition of human MAOA


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL293004
PNG
(1-[3-(4-Hydroxy-phenyl)-5-(2-methoxy-phenyl)-4,5-d...)
Show SMILES COc1ccccc1C1CC(=NN1C(C)=O)c1ccc(O)cc1
PDB
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6.0n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Roma La Sapienza

Curated by ChEMBL


Assay Description
Binding affinity was evaluated against human monoamino oxidase A


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL303112
PNG
(1-[3-(2,4-Dihydroxy-phenyl)-5-(2-methoxy-phenyl)-4...)
Show SMILES COc1ccccc1C1CC(=NN1C(C)=O)c1ccc(O)cc1O
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7.0n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Roma La Sapienza

Curated by ChEMBL


Assay Description
Binding affinity was evaluated against human monoamino oxidase A


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL303112
PNG
(1-[3-(2,4-Dihydroxy-phenyl)-5-(2-methoxy-phenyl)-4...)
Show SMILES COc1ccccc1C1CC(=NN1C(C)=O)c1ccc(O)cc1O
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8.0n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Roma La Sapienza

Curated by ChEMBL


Assay Description
Binding affinity was evaluated against human monoamino oxidase A


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL293004
PNG
(1-[3-(4-Hydroxy-phenyl)-5-(2-methoxy-phenyl)-4,5-d...)
Show SMILES COc1ccccc1C1CC(=NN1C(C)=O)c1ccc(O)cc1
PDB
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9.0n/an/an/an/an/an/an/an/a



Universit£ degli Studi di Roma La Sapienza

Curated by ChEMBL


Assay Description
Binding affinity was evaluated against human monoamino oxidase A


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL66225
PNG
(1-Ethyl-phenoxathiine 10,10-dioxide)
Show SMILES CCc1cccc2Oc3ccccc3S(=O)(=O)c12
PDB
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10.0n/an/an/an/an/an/an/an/a



Burroughs Wellcome Co.

Curated by ChEMBL


Assay Description
In vitro binding affinity of the compound towards Monoamine Oxidase A in human


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1645549
PNG
(7-(Benzyloxy)-1-methyl-beta-carboline)
Show SMILES Cc1nccc2c3ccc(OCc4ccccc4)cc3[nH]c12
PDB
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12.6n/an/an/an/an/an/an/an/a



Facult£s Universitaires Notre-Dame de la Paix

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
HARMINE
PNG
(11h | 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE | 7-Met...)
Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21
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16.9n/an/an/an/an/an/an/an/a



Facult£s Universitaires Notre-Dame de la Paix

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
HARMINE
PNG
(11h | 7-METHOXY-1-METHYL-9H-BETA-CARBOLINE | 7-Met...)
Show SMILES COc1ccc2c(c1)[nH]c1c(C)nccc21
PDB
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17.0n/an/an/an/an/an/an/an/a



University of Namur

Curated by ChEMBL


Assay Description
Inhibition of MAO-A


Citation and Details
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1760713
PNG
(3-(anthracen-9-yl)-5-(4-nitrophenyl)-4,5-dihydro-1...)
Show SMILES [O-][N+](=O)c1ccc(cc1)C1CC(=NN1)c1c2ccccc2cc2ccccc12
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17.08n/an/an/an/an/an/an/an/a



Birla Institute of Technology

Curated by ChEMBL


Assay Description
Competitive inhibition of human recombinant MAO-A after 60 mins using p-tyramine as substrate by spectrophotometry


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL387778
PNG
((S)-2-amino-1-(4-butylthiophenyl)-propane)
Show SMILES CCCCSc1ccc(C[C@H](C)N)cc1
PDB
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22.0n/an/an/an/an/an/an/an/a



University of Santiago de Chile

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAOA expressed in Pichia pastoris


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL602464
PNG
(8-(3-Bromobenzyloxy)caffeine)
Show SMILES Cn1c(OCc2cccc(Br)c2)nc2n(C)c(=O)n(C)c(=O)c12
PDB
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23.0n/an/an/an/an/an/an/an/a



North-West University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAOA assessed as 4-hydroxyquinoline formation by fluorometry


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1645552
PNG
(7-(Pyridin-3-ylmethoxy)-1-methyl-beta-carboline)
Show SMILES Cc1nccc2c3ccc(OCc4cccnc4)cc3[nH]c12
PDB
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24.9n/an/an/an/an/an/an/an/a



Facult£s Universitaires Notre-Dame de la Paix

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL14355
PNG
(2-(1-Methyl-9H-beta-carbolin-7-yloxy)-ethanol | 7-...)
Show SMILES Cc1nccc2c3ccc(OCCO)cc3[nH]c12
PDB
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28.4n/an/an/an/an/an/an/an/a



Facult£s Universitaires Notre-Dame de la Paix

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1645546
PNG
(7-(2-Methoxyethoxy)-1-methyl-beta-carboline)
Show SMILES COCCOc1ccc2c(c1)[nH]c1c(C)nccc21
PDB
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29.5n/an/an/an/an/an/an/an/a



Facult£s Universitaires Notre-Dame de la Paix

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL229472
PNG
((S)-2-amino-1-(4-propylthiophenyl)-propane)
Show SMILES CCCSc1ccc(C[C@H](C)N)cc1
PDB
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30.0n/an/an/an/an/an/an/an/a



University of Santiago de Chile

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAOA expressed in Pichia pastoris


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1760721
PNG
(3-(anthracen-9-yl)-5-(3-nitrophenyl)-4,5-dihydro-1...)
Show SMILES [O-][N+](=O)c1cccc(c1)C1CC(=NN1)c1c2ccccc2cc2ccccc12
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32.16n/an/an/an/an/an/an/an/a



Birla Institute of Technology

Curated by ChEMBL


Assay Description
Competitive inhibition of human recombinant MAO-A after 60 mins using p-tyramine as substrate by spectrophotometry


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1645553
PNG
(7-(Pyridin-4-ylmethoxy)-1-methyl-beta-carboline)
Show SMILES Cc1nccc2c3ccc(OCc4ccncc4)cc3[nH]c12
PDB
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35.4n/an/an/an/an/an/an/an/a



Facult£s Universitaires Notre-Dame de la Paix

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL602260
PNG
(8-(3-Chlorobenzyloxy)caffeine)
Show SMILES Cn1c(OCc2cccc(Cl)c2)nc2n(C)c(=O)n(C)c(=O)c12
PDB
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36.0n/an/an/an/an/an/an/an/a



North-West University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAOA assessed as 4-hydroxyquinoline formation by fluorometry


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL602466
PNG
(8-[(3-Trifluoromethyl)benzyloxy]caffeine)
Show SMILES Cn1c(OCc2cccc(c2)C(F)(F)F)nc2n(C)c(=O)n(C)c(=O)c12
PDB
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51.0n/an/an/an/an/an/an/an/a



North-West University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAOA assessed as 4-hydroxyquinoline formation by fluorometry


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1813523
PNG
Show SMILES Brc1ccc(COc2ccc3C(=O)NC(=O)c3c2)cc1
PDB
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58.0n/an/an/an/an/an/an/an/a



North-West University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAOA expressed in insect cells using kynuramine substrate using Cheng and Prusoff equation by fluorescence spectrosco...


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL466872
PNG
((E)-5-Styrylisatin)
Show SMILES O=C1Nc2ccc(\C=C\c3ccccc3)cc2C1=O
PDB
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61.0n/an/an/an/an/an/an/an/a



North-West University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAOA expressed in insect cells by fluorescence assay


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1760718
PNG
(2-(3-(anthracen-9-yl)-4,5-dihydro-1H-pyrazol-5-yl)...)
Show SMILES Oc1ccccc1C1CC(=NN1)c1c2ccccc2cc2ccccc12
PDB
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69.91n/an/an/an/an/an/an/an/a



Birla Institute of Technology

Curated by ChEMBL


Assay Description
Competitive inhibition of human recombinant MAO-A after 60 mins using p-tyramine as substrate by spectrophotometry


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL387777
PNG
((S)-2-amino-1-(4-ethylthiophenyl)-propane)
Show SMILES CCSc1ccc(C[C@H](C)N)cc1
PDB
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75.0n/an/an/an/an/an/an/an/a



University of Santiago de Chile

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAOA expressed in Pichia pastoris


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1760719
PNG
(4-(3-(anthracen-9-yl)-4,5-dihydro-1H-pyrazol-5-yl)...)
Show SMILES Oc1ccc(C2CC(=NN2)c2c3ccccc3cc3ccccc23)c(O)c1
PDB
MMDB

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81.54n/an/an/an/an/an/an/an/a



Birla Institute of Technology

Curated by ChEMBL


Assay Description
Competitive inhibition of human recombinant MAO-A after 60 mins using p-tyramine as substrate by spectrophotometry


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1796449
PNG
Show SMILES COc1ccc(NC(=S)N2N=C(CC2c2ccc(O)cc2)c2ccccc2)cc1
PDB
MMDB

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90.0n/an/an/an/an/an/an/an/a



Birla Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of human MAO-A expressed in BTI insect cells using p-tyramine as substrate after 60 mins


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1645554
PNG
(7-(Naphthalen-2-ylmethoxy)-1-methyl-beta-carboline)
Show SMILES Cc1nccc2c3ccc(OCc4ccc5ccccc5c4)cc3[nH]c12
PDB
MMDB

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100.0n/an/an/an/an/an/an/an/a



Facult£s Universitaires Notre-Dame de la Paix

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1796445
PNG
Show SMILES COc1cccc(NC(=S)N2N=C(CC2c2ccccc2O)c2ccccc2)c1
PDB
MMDB

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100.0n/an/an/an/an/an/an/an/a



Birla Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of human MAO-A expressed in BTI insect cells using p-tyramine as substrate after 60 mins


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1796451
PNG
Show SMILES Cc1cccc(NC(=S)N2N=C(CC2c2ccc(O)cc2)c2ccccc2)c1
PDB
MMDB

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130.0n/an/an/an/an/an/an/an/a



Birla Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of human MAO-A expressed in BTI insect cells using p-tyramine as substrate after 60 mins


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL439193
PNG
((S)-2-amino-1-(4-methylthiophenyl)-propane)
Show SMILES CSc1ccc(C[C@H](C)N)cc1
PDB
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133.0n/an/an/an/an/an/an/an/a



University of Santiago de Chile

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAOA expressed in Pichia pastoris


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1642676
PNG
(5-Phenylisatin)
Show SMILES O=C1Nc2ccc(cc2C1=O)-c1ccccc1
PDB
MMDB

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148.0n/an/an/an/an/an/an/an/a



North-West University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAOA expressed in insect cells by fluorescence assay


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1796461
PNG
Show SMILES NC(=N)N1N=C(CC1c1ccc(Cl)cc1)c1ccccc1
PDB
MMDB

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150.0n/an/an/an/an/an/an/an/a



Birla Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of human MAO-A expressed in BTI insect cells using p-tyramine as substrate after 60 mins


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1796443
PNG
Show SMILES COc1ccc(NC(=S)N2N=C(CC2c2ccccc2O)c2ccccc2)cc1
PDB
MMDB

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170.0n/an/an/an/an/an/an/an/a



Birla Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of human MAO-A expressed in BTI insect cells using p-tyramine as substrate after 60 mins


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL589765
PNG
(8-(3-Methylbenzyloxy)caffeine)
Show SMILES Cc1cccc(COc2nc3n(C)c(=O)n(C)c(=O)c3n2C)c1
PDB
MMDB

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180.0n/an/an/an/an/an/an/an/a



North-West University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAOA assessed as 4-hydroxyquinoline formation by fluorometry


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL602465
PNG
(8-(3-Fluorobenzyloxy)caffeine)
Show SMILES Cn1c(OCc2cccc(F)c2)nc2n(C)c(=O)n(C)c(=O)c12
PDB
MMDB

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180.0n/an/an/an/an/an/an/an/a



North-West University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAOA assessed as 4-hydroxyquinoline formation by fluorometry


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1813522
PNG
Show SMILES O=C1NC(=O)c2cc(Oc3ccc4ccccc4c3)ccc12
PDB
MMDB

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200.0n/an/an/an/an/an/an/an/a



North-West University

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAOA expressed in insect cells using kynuramine substrate using Cheng and Prusoff equation by fluorescence spectrosco...


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1760720
PNG
(2-(3-(anthracen-9-yl)-4,5-dihydro-1H-pyrazol-5-yl)...)
Show SMILES C1C(NN=C1c1c2ccccc2cc2ccccc12)c1ccccn1
PDB
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205.45n/an/an/an/an/an/an/an/a



Birla Institute of Technology

Curated by ChEMBL


Assay Description
Competitive inhibition of human recombinant MAO-A after 60 mins using p-tyramine as substrate by spectrophotometry


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1760714
PNG
(4-(3-(anthracen-9-yl)-4,5-dihydro-1H-pyrazol-5-yl)...)
Show SMILES Oc1ccc(cc1)C1CC(=NN1)c1c2ccccc2cc2ccccc12
PDB
MMDB

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225.13n/an/an/an/an/an/an/an/a



Birla Institute of Technology

Curated by ChEMBL


Assay Description
Competitive inhibition of human recombinant MAO-A after 60 mins using p-tyramine as substrate by spectrophotometry


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1796448
PNG
Show SMILES Cc1ccccc1NC(=S)N1N=C(CC1c1ccccc1O)c1ccccc1
PDB
MMDB

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250.0n/an/an/an/an/an/an/an/a



Birla Institute of Technology

Curated by ChEMBL


Assay Description
Inhibition of human MAO-A expressed in BTI insect cells using p-tyramine as substrate after 60 mins


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1760716
PNG
(3-(anthracen-9-yl)-5-p-tolyl-4,5-dihydro-1H-pyrazo...)
Show SMILES Cc1ccc(cc1)C1CC(=NN1)c1c2ccccc2cc2ccccc12
PDB
MMDB

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250.27n/an/an/an/an/an/an/an/a



Birla Institute of Technology

Curated by ChEMBL


Assay Description
Competitive inhibition of human recombinant MAO-A after 60 mins using p-tyramine as substrate by spectrophotometry


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1645557
PNG
(7-(Ethyloxymorpholine)-1-methyl-beta-carboline)
Show SMILES Cc1nccc2c3ccc(OCCN4CCOCC4)cc3[nH]c12
PDB
MMDB

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255.7n/an/an/an/an/an/an/an/a



Facult£s Universitaires Notre-Dame de la Paix

Curated by ChEMBL


Assay Description
Inhibition of human recombinant MAO-A expressed in baculovirus-infected Bacillus thuringiensis israelensis cells after 1 hr by two-step bioluminescen...


Citation and Details
More data for this
Ligand-Target Pair
Monoamine Oxidase Type A (MAO-A)


(Homo sapiens)
CHEMBL1760715
PNG
(3-(anthracen-9-yl)-5-(4-chlorophenyl)-4,5-dihydro-...)
Show SMILES Clc1ccc(cc1)C1CC(=NN1)c1c2ccccc2cc2ccccc12
PDB
MMDB

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281.19n/an/an/an/an/an/an/an/a



Birla Institute of Technology

Curated by ChEMBL


Assay Description
Competitive inhibition of human recombinant MAO-A after 60 mins using p-tyramine as substrate by spectrophotometry


Citation and Details
More data for this
Ligand-Target Pair
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