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Compile Data Set for Download or QSAR

Found 33 hits for UniProtKB: P01589    Zinc 0: unavailable per Zinc DB. Zinc 1: purchasable, 2 weeks to supply. Zinc 2: made on demand. Zinc 4: potentially available
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL429852
PNG
(5-[2,3-DICHLORO-4-(5-{1-[2-(2-GUANIDINO-4-METHYL-P...)
Show SMILES CC(C)CC([NH+]=C(N)N)C(=O)NCC(=O)N1CCC(CC1)c1cc(nn1C)-c1ccc(OCc2ccc(o2)C([O-])=O)c(Cl)c1Cl
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
ChEBI
CHEMBL
PC cid
PC sid
PDB
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a 60.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL182704
PNG
(5-[2,3-Dichloro-4-(1-methyl-5-{1-[3-(N-methyl-guan...)
Show SMILES CN(CCCNS(=O)(=O)N1CCC(CC1)c1cc(nn1C)-c1ccc(OCc2ccc(o2)C(O)=O)c(Cl)c1Cl)C(N)=N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a 600.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL419362
PNG
((S)-2-[2-((R)-1-Carbamimidoyl-piperidin-3-yl)-acet...)
Show SMILES COC(=O)[C@H](Cc1ccc(cc1)C#Cc1ccccc1)NC(=O)C[C@H]1CCCN(C1)C(N)=N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
MMDB
PC cid
PC sid
PDB
ZINC 0

Patents

AffyNet 
Article
PubMed
n/an/a 3000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL106187
PNG
((R)-2-Cyclohexyl-N-(2-{4-[5-(2,3-dichloro-phenyl)-...)
Show SMILES NC(N)=N[C@H](C1CCCCC1)C(=O)NCC(=O)N1CCC(CC1)c1cc(n[nH]1)-c1cccc(Cl)c1Cl
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
ZINC 0

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 6000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL181294
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES CN(C)C(=O)[C@H](CCNC(=O)N1CCC(CC1)c1cc(nn1C)-c1cccc(Cl)c1Cl)N=C(N)N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a 7000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL362041
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES CCN(CC)C(=O)[C@H](CCNC(=O)N1CCC(CC1)c1cc(nn1C)-c1cccc(Cl)c1Cl)N=C(N)N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 11000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL179083
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES CN(CCCNS(=O)(=O)N1CCC(CC1)c1cc(nn1C)-c1cccc(Cl)c1Cl)C(N)=N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a 14000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL181692
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES CN(CCCNC(=O)N1CCC(CC1)c1cc(nn1C)-c1cccc(Cl)c1Cl)C(N)=N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a 16000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL181983
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES Cn1nc(cc1C1CCN(CC1)C(=O)NCC[C@H](N=C(N)N)C(=O)N1CCCC1)-c1cccc(Cl)c1Cl
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a 20000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL180014
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES CC(C)C[C@H](CCNC(=O)N1CCC(CC1)c1cc(nn1C)-c1cccc(Cl)c1Cl)N=C(N)N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a 23000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL180601
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES Cn1nc(cc1C1CCN(CC1)S(=O)(=O)NCCCNC(N)=N)-c1cccc(Cl)c1Cl
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 23000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL180756
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES Cn1nc(cc1C1CCN(CC1)C(=O)NCCCNC(N)=N)-c1cccc(Cl)c1Cl
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 29000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL361550
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES CC(C)C[C@H](CCNS(=O)(=O)N1CCC(CC1)c1cc(nn1C)-c1cccc(Cl)c1Cl)N=C(N)N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a 30000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL178800
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES CCCN(CCCNS(=O)(=O)N1CCC(CC1)c1cc(nn1C)-c1cccc(Cl)c1Cl)C(N)=N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a 32000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL182098
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES CC(C)N(CCCNS(=O)(=O)N1CCC(CC1)c1cc(nn1C)-c1cccc(Cl)c1Cl)C(N)=N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a 48000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL427132
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES CC(C)[C@H](CCNC(=O)N1CCC(CC1)c1cc(nn1C)-c1cccc(Cl)c1Cl)N=C(N)N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a 55000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL181558
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES C[C@H](CCNC(=O)N1CCC(CC1)c1cc(nn1C)-c1cccc(Cl)c1Cl)NC(N)=N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a 57000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL369721
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES CCN(CC1CC1)C(=O)[C@H](CCNC(=O)N1CCC(CC1)c1cc(nn1C)-c1cccc(Cl)c1Cl)N=C(N)N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a 60000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL181841
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES CC(=O)N1CCN(CC1)C(=O)[C@H](CCNC(=O)N1CCC(CC1)c1cc(nn1C)-c1cccc(Cl)c1Cl)N=C(N)N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a 60000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL181987
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES CC(C)[C@H](CCNS(=O)(=O)N1CCC(CC1)c1cc(nn1C)-c1cccc(Cl)c1Cl)N=C(N)N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a 76000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL179076
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES C[C@H](CCNS(=O)(=O)N1CCC(CC1)c1cc(nn1C)-c1cccc(Cl)c1Cl)NC(N)=N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a 90000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL179116
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES Cn1nc(cc1C1CCN(CC1)C(=O)NCCNC(N)=N)-c1cccc(Cl)c1Cl
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Patents


Similars

AffyNet 
Article
PubMed
n/an/a>100000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL181513
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES CC(C)[C@@H](CCNS(=O)(=O)N1CCC(CC1)c1cc(nn1C)-c1cccc(Cl)c1Cl)N=C(N)N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a>100000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL360913
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES Cn1nc(cc1C1CCN(CC1)S(=O)(=O)NCCNC(N)=N)-c1cccc(Cl)c1Cl
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Patents


Similars

AffyNet 
Article
PubMed
n/an/a>100000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL181019
PNG
(4-({4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol...)
Show SMILES Cn1nc(cc1C1CCN(CC1)C(=O)NCC[C@H](N=C(N)N)C(O)=O)-c1cccc(Cl)c1Cl
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a>100000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL362026
PNG
(4-({4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol...)
Show SMILES COC(=O)[C@H](CCNC(=O)N1CCC(CC1)c1cc(nn1C)-c1cccc(Cl)c1Cl)N=C(N)N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a>100000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL360778
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES CC(C)[C@@H](CCNC(=O)N1CCC(CC1)c1cc(nn1C)-c1cccc(Cl)c1Cl)N=C(N)N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a>100000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL359895
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES Cn1nc(cc1C1CCN(CC1)C(=O)NCC[C@H](N=C(N)N)C(=O)N1CCC2CCCCC2C1)-c1cccc(Cl)c1Cl
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a>100000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL361641
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES CNC(=O)[C@H](CCNC(=O)N1CCC(CC1)c1cc(nn1C)-c1cccc(Cl)c1Cl)N=C(N)N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a>100000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL181189
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES CC(C)N(CCCNC(=O)N1CCC(CC1)c1cc(nn1C)-c1cccc(Cl)c1Cl)C(N)=N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a>100000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL180764
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES Cn1nc(cc1C1CCN(CC1)S(=O)(=O)NCCCCNC(N)=N)-c1cccc(Cl)c1Cl
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Patents


Similars

AffyNet 
Article
PubMed
n/an/a>100000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL178466
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES Cn1nc(cc1C1CCN(CC1)C(=O)NCCCCNC(N)=N)-c1cccc(Cl)c1Cl
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a>100000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair
Interleukin-2 receptor alpha chain


(Homo sapiens)
CHEMBL178414
PNG
(4-[5-(2,3-Dichloro-phenyl)-2-methyl-2H-pyrazol-3-y...)
Show SMILES CCCN(CCCNC(=O)N1CCC(CC1)c1cc(nn1C)-c1cccc(Cl)c1Cl)C(N)=N
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a>100000.0n/an/an/an/an/an/a



Sunesis Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Inhibitory concentration against interleukin-2 binding


Citation and Details
More data for this
Ligand-Target Pair