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Compile Data Set for Download or QSAR

Found 16 hits of ic50 data for polymerid = 50000392   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Growth factor receptor-bound protein 2


(Mus musculus)
BDBM50089524
PNG
(Actinomycin D analogue | CHEMBL2369548)
Show SMILES CC(C)[C@@H]1NC(=O)CN(C)C(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@@H](NC(=O)CN(C)C(=O)[C@@H]6CCCN6C(=O)[C@@H](Cc6ccc(O)cc6)NC5=O)C(C)C)c4nc23)[C@@H](C)OC1=O
Show InChI InChI=1S/C68H82N12O18/c1-31(2)50-67(94)96-35(7)52(61(88)70-42(27-37-16-20-39(81)21-17-37)63(90)79-25-11-13-44(79)65(92)77(9)29-46(83)72-50)75-59(86)41-24-15-33(5)57-54(41)74-55-48(49(69)56(85)34(6)58(55)98-57)60(87)76-53-36(8)97-68(95)51(32(3)4)73-47(84)30-78(10)66(93)45-14-12-26-80(45)64(91)43(71-62(53)89)28-38-18-22-40(82)23-19-38/h15-24,31-32,35-36,42-45,50-53,81-82H,11-14,25-30,69H2,1-10H3,(H,70,88)(H,71,89)(H,72,83)(H,73,84)(H,75,86)(H,76,87)/t35-,36-,42-,43-,44+,45+,50+,51+,52+,53+/m1/s1
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Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determined


Bioorg Med Chem Lett 10: 1455-7 (2000)

More data for this
Ligand-Target Pair
Growth factor receptor-bound protein 2


(Mus musculus)
BDBM50089529
PNG
(Actinomycin D analogue | CHEMBL2369549)
Show SMILES CC(C)[C@H]1NC(=O)[C@@H](NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@H](Cc6ccc(O)cc6)NC(=O)CN(C)C(=O)[C@@H]6CCCN6C(=O)[C@H](NC5=O)C(C)C)c4nc23)[C@@H](C)OC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CN(C)C(=O)[C@@H]2CCCN2C1=O
Show InChI InChI=1S/C68H82N12O18/c1-31(2)50-65(92)79-25-11-13-44(79)63(90)77(9)29-46(83)70-42(27-37-16-20-39(81)21-17-37)67(94)96-35(7)52(61(88)73-50)75-59(86)41-24-15-33(5)57-54(41)72-55-48(49(69)56(85)34(6)58(55)98-57)60(87)76-53-36(8)97-68(95)43(28-38-18-22-40(82)23-19-38)71-47(84)30-78(10)64(91)45-14-12-26-80(45)66(93)51(32(3)4)74-62(53)89/h15-24,31-32,35-36,42-45,50-53,81-82H,11-14,25-30,69H2,1-10H3,(H,70,83)(H,71,84)(H,73,88)(H,74,89)(H,75,86)(H,76,87)/t35-,36-,42+,43+,44+,45+,50-,51-,52+,53+/m1/s1
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n/an/a 800n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determined


Bioorg Med Chem Lett 10: 1455-7 (2000)

More data for this
Ligand-Target Pair
Growth factor receptor-bound protein 2


(Mus musculus)
BDBM50089533
PNG
(Actinomycin D analogue | CHEMBL2369547)
Show SMILES CC(C)[C@H]1NC(=O)[C@@H](NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@@H](Cc6ccc(O)cc6)NC(=O)CN(C)C(=O)[C@@H]6CCCN6C(=O)[C@H](NC5=O)C(C)C)c4nc23)[C@@H](C)OC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)CN(C)C(=O)[C@@H]2CCCN2C1=O
Show InChI InChI=1S/C68H82N12O18/c1-31(2)50-65(92)79-25-11-13-44(79)63(90)77(9)29-46(83)70-42(27-37-16-20-39(81)21-17-37)67(94)96-35(7)52(61(88)73-50)75-59(86)41-24-15-33(5)57-54(41)72-55-48(49(69)56(85)34(6)58(55)98-57)60(87)76-53-36(8)97-68(95)43(28-38-18-22-40(82)23-19-38)71-47(84)30-78(10)64(91)45-14-12-26-80(45)66(93)51(32(3)4)74-62(53)89/h15-24,31-32,35-36,42-45,50-53,81-82H,11-14,25-30,69H2,1-10H3,(H,70,83)(H,71,84)(H,73,88)(H,74,89)(H,75,86)(H,76,87)/t35-,36-,42-,43-,44+,45+,50-,51-,52+,53+/m1/s1
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n/an/a 800n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determined


Bioorg Med Chem Lett 10: 1455-7 (2000)

More data for this
Ligand-Target Pair
Growth factor receptor-bound protein 2


(Mus musculus)
BDBM50089533
PNG
(Actinomycin D analogue | CHEMBL2369547)
Show SMILES CC(C)[C@H]1NC(=O)[C@@H](NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@@H](Cc6ccc(O)cc6)NC(=O)CN(C)C(=O)[C@@H]6CCCN6C(=O)[C@H](NC5=O)C(C)C)c4nc23)[C@@H](C)OC(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)CN(C)C(=O)[C@@H]2CCCN2C1=O
Show InChI InChI=1S/C68H82N12O18/c1-31(2)50-65(92)79-25-11-13-44(79)63(90)77(9)29-46(83)70-42(27-37-16-20-39(81)21-17-37)67(94)96-35(7)52(61(88)73-50)75-59(86)41-24-15-33(5)57-54(41)72-55-48(49(69)56(85)34(6)58(55)98-57)60(87)76-53-36(8)97-68(95)43(28-38-18-22-40(82)23-19-38)71-47(84)30-78(10)64(91)45-14-12-26-80(45)66(93)51(32(3)4)74-62(53)89/h15-24,31-32,35-36,42-45,50-53,81-82H,11-14,25-30,69H2,1-10H3,(H,70,83)(H,71,84)(H,73,88)(H,74,89)(H,75,86)(H,76,87)/t35-,36-,42-,43-,44+,45+,50-,51-,52+,53+/m1/s1
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n/an/a 800n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determined


Bioorg Med Chem Lett 10: 1455-7 (2000)

More data for this
Ligand-Target Pair
Growth factor receptor-bound protein 2


(Mus musculus)
BDBM50089529
PNG
(Actinomycin D analogue | CHEMBL2369549)
Show SMILES CC(C)[C@H]1NC(=O)[C@@H](NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@H](Cc6ccc(O)cc6)NC(=O)CN(C)C(=O)[C@@H]6CCCN6C(=O)[C@H](NC5=O)C(C)C)c4nc23)[C@@H](C)OC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CN(C)C(=O)[C@@H]2CCCN2C1=O
Show InChI InChI=1S/C68H82N12O18/c1-31(2)50-65(92)79-25-11-13-44(79)63(90)77(9)29-46(83)70-42(27-37-16-20-39(81)21-17-37)67(94)96-35(7)52(61(88)73-50)75-59(86)41-24-15-33(5)57-54(41)72-55-48(49(69)56(85)34(6)58(55)98-57)60(87)76-53-36(8)97-68(95)43(28-38-18-22-40(82)23-19-38)71-47(84)30-78(10)64(91)45-14-12-26-80(45)66(93)51(32(3)4)74-62(53)89/h15-24,31-32,35-36,42-45,50-53,81-82H,11-14,25-30,69H2,1-10H3,(H,70,83)(H,71,84)(H,73,88)(H,74,89)(H,75,86)(H,76,87)/t35-,36-,42+,43+,44+,45+,50-,51-,52+,53+/m1/s1
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n/an/a 800n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determined


Bioorg Med Chem Lett 10: 1455-7 (2000)

More data for this
Ligand-Target Pair
Growth factor receptor-bound protein 2


(Mus musculus)
BDBM50089527
PNG
(Actinomycin D analogue | CHEMBL2372240)
Show SMILES CC(C)[C@H]1NC(=O)[C@@H](NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@H](Cc6ccccc6)NC(=O)CN(C)C(=O)[C@@H]6CCCN6C(=O)[C@H](NC5=O)C(C)C)c4nc23)[C@@H](C)OC(=O)[C@H](Cc2ccccc2)NC(=O)CN(C)C(=O)[C@@H]2CCCN2C1=O
Show InChI InChI=1S/C68H82N12O16/c1-33(2)50-65(90)79-27-17-23-44(79)63(88)77(9)31-46(81)70-42(29-39-19-13-11-14-20-39)67(92)94-37(7)52(61(86)73-50)75-59(84)41-26-25-35(5)57-54(41)72-55-48(49(69)56(83)36(6)58(55)96-57)60(85)76-53-38(8)95-68(93)43(30-40-21-15-12-16-22-40)71-47(82)32-78(10)64(89)45-24-18-28-80(45)66(91)51(34(3)4)74-62(53)87/h11-16,19-22,25-26,33-34,37-38,42-45,50-53H,17-18,23-24,27-32,69H2,1-10H3,(H,70,81)(H,71,82)(H,73,86)(H,74,87)(H,75,84)(H,76,85)/t37-,38-,42+,43+,44+,45+,50-,51-,52+,53+/m1/s1
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Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determined


Bioorg Med Chem Lett 10: 1455-7 (2000)

More data for this
Ligand-Target Pair
Growth factor receptor-bound protein 2


(Mus musculus)
BDBM50089520
PNG
(Actinomycin D analogue | CHEMBL2372235)
Show SMILES CC(C)[C@H]1NC(=O)CN(C)C(=O)[C@@H]2CCCN2C(=O)[C@H](NC(=O)[C@@H](NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@H](NC(=O)CN(C)C(=O)[C@@H]6CCCN6C(=O)[C@H](NC5=O)C(C)C)C(C)C)c4nc23)[C@@H](C)OC1=O)C(C)C
Show InChI InChI=1S/C60H82N12O16/c1-25(2)40-57(82)71-21-15-17-34(71)55(80)69(13)23-36(73)62-42(27(5)6)59(84)86-31(11)44(53(78)65-40)67-51(76)33-20-19-29(9)49-46(33)64-47-38(39(61)48(75)30(10)50(47)88-49)52(77)68-45-32(12)87-60(85)43(28(7)8)63-37(74)24-70(14)56(81)35-18-16-22-72(35)58(83)41(26(3)4)66-54(45)79/h19-20,25-28,31-32,34-35,40-45H,15-18,21-24,61H2,1-14H3,(H,62,73)(H,63,74)(H,65,78)(H,66,79)(H,67,76)(H,68,77)/t31-,32-,34+,35+,40-,41-,42-,43-,44+,45+/m1/s1
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n/an/a 1.00E+3n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determined


Bioorg Med Chem Lett 10: 1455-7 (2000)

More data for this
Ligand-Target Pair
Growth factor receptor-bound protein 2


(Mus musculus)
BDBM50089525
PNG
(Actinomycin D analogue | CHEMBL2372236)
Show SMILES CC(C)[C@@H]1NC(=O)CN(C)C(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@@H](NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@@H](NC(=O)CN(C)C(=O)[C@@H]6CCCN6C(=O)[C@@H](Cc6ccccc6)NC5=O)C(C)C)c4nc23)[C@@H](C)OC1=O
Show InChI InChI=1S/C68H82N12O16/c1-33(2)50-67(92)94-37(7)52(61(86)70-42(29-39-19-13-11-14-20-39)63(88)79-27-17-23-44(79)65(90)77(9)31-46(81)72-50)75-59(84)41-26-25-35(5)57-54(41)74-55-48(49(69)56(83)36(6)58(55)96-57)60(85)76-53-38(8)95-68(93)51(34(3)4)73-47(82)32-78(10)66(91)45-24-18-28-80(45)64(89)43(71-62(53)87)30-40-21-15-12-16-22-40/h11-16,19-22,25-26,33-34,37-38,42-45,50-53H,17-18,23-24,27-32,69H2,1-10H3,(H,70,86)(H,71,87)(H,72,81)(H,73,82)(H,75,84)(H,76,85)/t37-,38-,42-,43-,44+,45+,50+,51+,52+,53+/m1/s1
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n/an/a 1.20E+3n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determined


Bioorg Med Chem Lett 10: 1455-7 (2000)

More data for this
Ligand-Target Pair
Growth factor receptor-bound protein 2


(Mus musculus)
BDBM50089532
PNG
(Actinomycin D analogue | CHEMBL2372231)
Show SMILES COc1ccc(C[C@H]2NC(=O)[C@@H](NC(=O)c3ccc(C)c4oc5c(C)c(=O)c(N)c(C(=O)N[C@H]6[C@@H](C)OC(=O)[C@@H](NC(=O)CN(C)C(=O)[C@@H]7CCCN7C(=O)[C@@H](Cc7ccc(OC)cc7)NC6=O)C(C)C)c5nc34)[C@@H](C)OC(=O)[C@@H](NC(=O)CN(C)C(=O)[C@@H]3CCCN3C2=O)C(C)C)cc1
Show InChI InChI=1S/C70H86N12O18/c1-33(2)52-69(94)98-37(7)54(63(88)72-44(29-39-18-22-41(96-11)23-19-39)65(90)81-27-13-15-46(81)67(92)79(9)31-48(83)74-52)77-61(86)43-26-17-35(5)59-56(43)76-57-50(51(71)58(85)36(6)60(57)100-59)62(87)78-55-38(8)99-70(95)53(34(3)4)75-49(84)32-80(10)68(93)47-16-14-28-82(47)66(91)45(73-64(55)89)30-40-20-24-42(97-12)25-21-40/h17-26,33-34,37-38,44-47,52-55H,13-16,27-32,71H2,1-12H3,(H,72,88)(H,73,89)(H,74,83)(H,75,84)(H,77,86)(H,78,87)/t37-,38-,44-,45-,46+,47+,52+,53+,54+,55+/m1/s1
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n/an/a 1.50E+3n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determined


Bioorg Med Chem Lett 10: 1455-7 (2000)

More data for this
Ligand-Target Pair
Growth factor receptor-bound protein 2


(Mus musculus)
BDBM50089522
PNG
(Actinomycin D analogue | CHEMBL2372234)
Show SMILES CC(C)[C@H]1NC(=O)[C@@H](NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@@H](Cc6ccccc6)NC(=O)CN(C)C(=O)[C@@H]6CCCN6C(=O)[C@H](NC5=O)C(C)C)c4nc23)[C@@H](C)OC(=O)[C@@H](Cc2ccccc2)NC(=O)CN(C)C(=O)[C@@H]2CCCN2C1=O
Show InChI InChI=1S/C68H82N12O16/c1-33(2)50-65(90)79-27-17-23-44(79)63(88)77(9)31-46(81)70-42(29-39-19-13-11-14-20-39)67(92)94-37(7)52(61(86)73-50)75-59(84)41-26-25-35(5)57-54(41)72-55-48(49(69)56(83)36(6)58(55)96-57)60(85)76-53-38(8)95-68(93)43(30-40-21-15-12-16-22-40)71-47(82)32-78(10)64(89)45-24-18-28-80(45)66(91)51(34(3)4)74-62(53)87/h11-16,19-22,25-26,33-34,37-38,42-45,50-53H,17-18,23-24,27-32,69H2,1-10H3,(H,70,81)(H,71,82)(H,73,86)(H,74,87)(H,75,84)(H,76,85)/t37-,38-,42-,43-,44+,45+,50-,51-,52+,53+/m1/s1
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n/an/a 1.80E+3n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determined


Bioorg Med Chem Lett 10: 1455-7 (2000)

More data for this
Ligand-Target Pair
Growth factor receptor-bound protein 2


(Mus musculus)
BDBM50089530
PNG
(Actinomycin D analogue | CHEMBL2372239)
Show SMILES COc1ccc(C[C@@H]2NC(=O)CN(C)C(=O)[C@@H]3CCCN3C(=O)[C@H](NC(=O)[C@@H](NC(=O)c3ccc(C)c4oc5c(C)c(=O)c(N)c(C(=O)N[C@H]6[C@@H](C)OC(=O)[C@H](Cc7ccc(OC)cc7)NC(=O)CN(C)C(=O)[C@@H]7CCCN7C(=O)[C@H](NC6=O)C(C)C)c5nc34)[C@@H](C)OC2=O)C(C)C)cc1
Show InChI InChI=1S/C70H86N12O18/c1-33(2)52-67(92)81-27-13-15-46(81)65(90)79(9)31-48(83)72-44(29-39-18-22-41(96-11)23-19-39)69(94)98-37(7)54(63(88)75-52)77-61(86)43-26-17-35(5)59-56(43)74-57-50(51(71)58(85)36(6)60(57)100-59)62(87)78-55-38(8)99-70(95)45(30-40-20-24-42(97-12)25-21-40)73-49(84)32-80(10)66(91)47-16-14-28-82(47)68(93)53(34(3)4)76-64(55)89/h17-26,33-34,37-38,44-47,52-55H,13-16,27-32,71H2,1-12H3,(H,72,83)(H,73,84)(H,75,88)(H,76,89)(H,77,86)(H,78,87)/t37-,38-,44+,45+,46+,47+,52-,53-,54+,55+/m1/s1
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n/an/a 2.00E+3n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determined


Bioorg Med Chem Lett 10: 1455-7 (2000)

More data for this
Ligand-Target Pair
Growth factor receptor-bound protein 2


(Mus musculus)
BDBM50089521
PNG
(Actinomycin D analogue | CHEMBL2372241)
Show SMILES COc1ccc(C[C@H]2NC(=O)CN(C)C(=O)[C@@H]3CCCN3C(=O)[C@H](NC(=O)[C@@H](NC(=O)c3ccc(C)c4oc5c(C)c(=O)c(N)c(C(=O)N[C@H]6[C@@H](C)OC(=O)[C@@H](Cc7ccc(OC)cc7)NC(=O)CN(C)C(=O)[C@@H]7CCCN7C(=O)[C@H](NC6=O)C(C)C)c5nc34)[C@@H](C)OC2=O)C(C)C)cc1
Show InChI InChI=1S/C70H86N12O18/c1-33(2)52-67(92)81-27-13-15-46(81)65(90)79(9)31-48(83)72-44(29-39-18-22-41(96-11)23-19-39)69(94)98-37(7)54(63(88)75-52)77-61(86)43-26-17-35(5)59-56(43)74-57-50(51(71)58(85)36(6)60(57)100-59)62(87)78-55-38(8)99-70(95)45(30-40-20-24-42(97-12)25-21-40)73-49(84)32-80(10)66(91)47-16-14-28-82(47)68(93)53(34(3)4)76-64(55)89/h17-26,33-34,37-38,44-47,52-55H,13-16,27-32,71H2,1-12H3,(H,72,83)(H,73,84)(H,75,88)(H,76,89)(H,77,86)(H,78,87)/t37-,38-,44-,45-,46+,47+,52-,53-,54+,55+/m1/s1
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n/an/a 2.00E+3n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determined


Bioorg Med Chem Lett 10: 1455-7 (2000)

More data for this
Ligand-Target Pair
Growth factor receptor-bound protein 2


(Mus musculus)
BDBM50089524
PNG
(Actinomycin D analogue | CHEMBL2369548)
Show SMILES CC(C)[C@@H]1NC(=O)CN(C)C(=O)[C@@H]2CCCN2C(=O)[C@@H](Cc2ccc(O)cc2)NC(=O)[C@@H](NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@@H](NC(=O)CN(C)C(=O)[C@@H]6CCCN6C(=O)[C@@H](Cc6ccc(O)cc6)NC5=O)C(C)C)c4nc23)[C@@H](C)OC1=O
Show InChI InChI=1S/C68H82N12O18/c1-31(2)50-67(94)96-35(7)52(61(88)70-42(27-37-16-20-39(81)21-17-37)63(90)79-25-11-13-44(79)65(92)77(9)29-46(83)72-50)75-59(86)41-24-15-33(5)57-54(41)74-55-48(49(69)56(85)34(6)58(55)98-57)60(87)76-53-36(8)97-68(95)51(32(3)4)73-47(84)30-78(10)66(93)45-14-12-26-80(45)64(91)43(71-62(53)89)28-38-18-22-40(82)23-19-38/h15-24,31-32,35-36,42-45,50-53,81-82H,11-14,25-30,69H2,1-10H3,(H,70,88)(H,71,89)(H,72,83)(H,73,84)(H,75,86)(H,76,87)/t35-,36-,42-,43-,44+,45+,50+,51+,52+,53+/m1/s1
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n/an/a 4.50E+3n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determined


Bioorg Med Chem Lett 10: 1455-7 (2000)

More data for this
Ligand-Target Pair
Growth factor receptor-bound protein 2


(Mus musculus)
BDBM50089528
PNG
(Actinomycin D | Actinomycin D analogue | Cosmegen ...)
Show SMILES CC(C)[C@H]1NC(=O)[C@@H](NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@@H]6CCCN6C(=O)[C@H](NC5=O)C(C)C)c4nc23)[C@@H](C)OC(=O)[C@H](C(C)C)N(C)C(=O)CN(C)C(=O)[C@@H]2CCCN2C1=O
Show InChI InChI=1S/C62H86N12O16/c1-27(2)42-59(84)73-23-17-19-36(73)57(82)69(13)25-38(75)71(15)48(29(5)6)61(86)88-33(11)44(55(80)65-42)67-53(78)35-22-21-31(9)51-46(35)64-47-40(41(63)50(77)32(10)52(47)90-51)54(79)68-45-34(12)89-62(87)49(30(7)8)72(16)39(76)26-70(14)58(83)37-20-18-24-74(37)60(85)43(28(3)4)66-56(45)81/h21-22,27-30,33-34,36-37,42-45,48-49H,17-20,23-26,63H2,1-16H3,(H,65,80)(H,66,81)(H,67,78)(H,68,79)/t33-,34-,36+,37+,42-,43-,44+,45+,48+,49+/m1/s1
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n/an/a 5.00E+3n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determined


Bioorg Med Chem Lett 10: 1455-7 (2000)

More data for this
Ligand-Target Pair
Growth factor receptor-bound protein 2


(Mus musculus)
BDBM50366641
PNG
(CHEMBL2369551)
Show SMILES CC[C@@H](C)[C@H]1NC(=O)[C@@H](NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@@H](NC(=O)CN(C)C(=O)[C@@H]6CCCN6C(=O)[C@H](NC5=O)[C@H](C)CC)C(C)C)c4nc23)[C@@H](C)OC(=O)[C@@H](NC(=O)CN(C)C(=O)[C@@H]2CCCN2C1=O)C(C)C
Show InChI InChI=1S/C62H86N12O16/c1-15-29(7)44-59(84)73-23-17-19-36(73)57(82)71(13)25-38(75)64-42(27(3)4)61(86)88-33(11)46(55(80)67-44)69-53(78)35-22-21-31(9)51-48(35)66-49-40(41(63)50(77)32(10)52(49)90-51)54(79)70-47-34(12)89-62(87)43(28(5)6)65-39(76)26-72(14)58(83)37-20-18-24-74(37)60(85)45(30(8)16-2)68-56(47)81/h21-22,27-30,33-34,36-37,42-47H,15-20,23-26,63H2,1-14H3,(H,64,75)(H,65,76)(H,67,80)(H,68,81)(H,69,78)(H,70,79)/t29-,30-,33-,34-,36+,37+,42+,43+,44-,45-,46+,47+/m1/s1
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n/an/a 5.90E+3n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determined


Bioorg Med Chem Lett 10: 1455-7 (2000)

More data for this
Ligand-Target Pair
Growth factor receptor-bound protein 2


(Mus musculus)
BDBM50366639
PNG
(CHEMBL2369550)
Show SMILES CC[C@@H](C)[C@H]1NC(=O)CN(C)C(=O)[C@@H]2CCCN2C(=O)[C@H](NC(=O)[C@@H](NC(=O)c2ccc(C)c3oc4c(C)c(=O)c(N)c(C(=O)N[C@H]5[C@@H](C)OC(=O)[C@H](NC(=O)CN(C)C(=O)[C@@H]6CCCN6C(=O)[C@H](NC5=O)[C@H](C)CC)[C@H](C)CC)c4nc23)[C@@H](C)OC1=O)[C@H](C)CC
Show InChI InChI=1S/C64H90N12O16/c1-15-29(5)44-61(86)75-25-19-21-38(75)59(84)73(13)27-40(77)66-46(31(7)17-3)63(88)90-35(11)48(57(82)69-44)71-55(80)37-24-23-33(9)53-50(37)68-51-42(43(65)52(79)34(10)54(51)92-53)56(81)72-49-36(12)91-64(89)47(32(8)18-4)67-41(78)28-74(14)60(85)39-22-20-26-76(39)62(87)45(30(6)16-2)70-58(49)83/h23-24,29-32,35-36,38-39,44-49H,15-22,25-28,65H2,1-14H3,(H,66,77)(H,67,78)(H,69,82)(H,70,83)(H,71,80)(H,72,81)/t29-,30-,31-,32-,35-,36-,38+,39+,44-,45-,46-,47-,48+,49+/m1/s1
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n/an/a 7.60E+3n/an/an/an/an/an/a



Korea Research Institute of Bioscience and Biotechnology

Curated by ChEMBL


Assay Description
In vitro binding assay of Shc-derived phosphopeptide to Growth factor receptor bound protein 2 SH2 in B104-1-1 cells was determined


Bioorg Med Chem Lett 10: 1455-7 (2000)

More data for this
Ligand-Target Pair