BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 41 hits of ki data for polymerid = 50000486,50000878,50004956   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aminopeptidase B


(Mus musculus)
BDBM50078120
PNG
((R)-1-{[(S)-2-((S)-1-Carboxy-1-methyl-2-phenyl-eth...)
Show SMILES C[C@H]([NH3+])P(O)(=O)C[C@@H](Cc1ccccc1)C(=O)N[C@@](C)(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C22H29N2O5P/c1-16(23)30(28,29)15-19(13-17-9-5-3-6-10-17)20(25)24-22(2,21(26)27)14-18-11-7-4-8-12-18/h3-12,16,19H,13-15,23H2,1-2H3,(H,24,25)(H,26,27)(H,28,29)/p+1/t16-,19-,22+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PubMed
>0.0000100n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on Aminopeptidase B using Arg p.NA as substrate


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Mus musculus)
BDBM50078122
PNG
((R)-1-{[(S)-2-((S)-1-Carboxy-1-methyl-2-phenyl-eth...)
Show SMILES C[C@@](Cc1ccccc1)(NC(=O)[C@H](Cc1ccccc1)CP(O)(=O)[C@@H]([NH3+])Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C28H33N2O5P/c1-28(27(32)33,19-23-15-9-4-10-16-23)30-26(31)24(17-21-11-5-2-6-12-21)20-36(34,35)25(29)18-22-13-7-3-8-14-22/h2-16,24-25H,17-20,29H2,1H3,(H,30,31)(H,32,33)(H,34,35)/p+1/t24-,25-,28+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

PubMed
>0.0000100n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on Aminopeptidase B using Arg p.NA as substrate


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50017480
PNG
(5-Amino-8-guanidino-2-(4-hydroxy-benzyl)-4-oxo-oct...)
Show SMILES N[C@@H](CCCNC(N)=N)C(=O)C[C@@H](Cc1ccc(O)cc1)C(O)=O
Show InChI InChI=1S/C16H24N4O4/c17-13(2-1-7-20-16(18)19)14(22)9-11(15(23)24)8-10-3-5-12(21)6-4-10/h3-6,11,13,21H,1-2,7-9,17H2,(H,23,24)(H4,18,19,20)/t11-,13+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
0.840n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Homo sapiens)
BDBM50036831
PNG
(6-Amino-2-mercapto-hexanoic acid | CHEMBL432852)
Show SMILES NCCCCC(S)C(O)=O
Show InChI InChI=1S/C6H13NO2S/c7-4-2-1-3-5(10)6(8)9/h5,10H,1-4,7H2,(H,8,9)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
0.900n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of arginylaminopeptidase (aminopeptidase B)


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50022743
PNG
(2,6-Diamino-hexane-1-thiol | CHEMBL68509)
Show SMILES NCCCC[C@@H](N)CS
Show InChI InChI=1S/C6H16N2S/c7-4-2-1-3-6(8)5-9/h6,9H,1-5,7-8H2/t6-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
0.910n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50017482
PNG
(5-Amino-2-benzyl-8-guanidino-4-oxo-octanoic acid |...)
Show SMILES N[C@@H](CCCNC(N)=N)C(=O)C[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N4O3/c17-13(7-4-8-20-16(18)19)14(21)10-12(15(22)23)9-11-5-2-1-3-6-11/h1-3,5-6,12-13H,4,7-10,17H2,(H,22,23)(H4,18,19,20)/t12-,13+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
2.5n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50017476
PNG
(5,9-Diamino-2-benzyl-4-oxo-nonanoic acid | CHEMBL2...)
Show SMILES NCCCC[C@H](N)C(=O)CC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O3/c17-9-5-4-8-14(18)15(19)11-13(16(20)21)10-12-6-2-1-3-7-12/h1-3,6-7,13-14H,4-5,8-11,17-18H2,(H,20,21)/t13?,14-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
4n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver; Ki value reporting the slope effect(Kis)


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50022751
PNG
(2-(3-Amino-2-mercapto-4-phenyl-butyrylamino)-4-met...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](S)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O3S/c1-10(2)8-13(16(20)21)18-15(19)14(22)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,22H,8-9,17H2,1-2H3,(H,18,19)(H,20,21)/t12-,13+,14+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
4.60n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50022751
PNG
(2-(3-Amino-2-mercapto-4-phenyl-butyrylamino)-4-met...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](S)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O3S/c1-10(2)8-13(16(20)21)18-15(19)14(22)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,22H,8-9,17H2,1-2H3,(H,18,19)(H,20,21)/t12-,13+,14+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
6.40n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Homo sapiens)
BDBM50036829
PNG
(2-Mercapto-4-methylsulfanyl-butyric acid | CHEMBL2...)
Show SMILES CSCCC(S)C(O)=O
Show InChI InChI=1S/C5H10O2S2/c1-9-3-2-4(8)5(6)7/h4,8H,2-3H2,1H3,(H,6,7)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
11n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of arginylaminopeptidase (aminopeptidase B)


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM23971
PNG
((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

PubMed
14n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Homo sapiens)
BDBM50036814
PNG
(2-Mercapto-4-methyl-pentanoic acid | CHEMBL27010)
Show SMILES CC(C)CC(S)C(O)=O
Show InChI InChI=1S/C6H12O2S/c1-4(2)3-5(9)6(7)8/h4-5,9H,3H2,1-2H3,(H,7,8)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
51n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of arginylaminopeptidase (aminopeptidase B)


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM23971
PNG
((2S)-2-[(2S,3R)-3-amino-2-hydroxy-4-phenylbutanami...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O4/c1-10(2)8-13(16(21)22)18-15(20)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,20)(H,21,22)/t12-,13+,14+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

PubMed
60n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50022748
PNG
(2-Amino-4-methyl-pentane-1-thiol | CHEMBL69349)
Show SMILES CC(C)C[C@@H](N)CS
Show InChI InChI=1S/C6H15NS/c1-5(2)3-6(7)4-8/h5-6,8H,3-4,7H2,1-2H3/t6-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
130n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50008434
PNG
(5-Amino-2-benzyl-7-methyl-4-oxo-octanoic acid | CH...)
Show SMILES CC(C)C[C@H](N)C(=O)CC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H23NO3/c1-11(2)8-14(17)15(18)10-13(16(19)20)9-12-6-4-3-5-7-12/h3-7,11,13-14H,8-10,17H2,1-2H3,(H,19,20)/t13?,14-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
170n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver; Ki value reporting the slope effect(Kis)


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Homo sapiens)
BDBM50008434
PNG
(5-Amino-2-benzyl-7-methyl-4-oxo-octanoic acid | CH...)
Show SMILES CC(C)C[C@H](N)C(=O)CC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H23NO3/c1-11(2)8-14(17)15(18)10-13(16(19)20)9-12-6-4-3-5-7-12/h3-7,11,13-14H,8-10,17H2,1-2H3,(H,19,20)/t13?,14-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
170n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Compound was tested for binding affinity towards arginyl aminopeptidase


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50405948
PNG
(CHEMBL2114365)
Show SMILES CC(C)C[C@@H](N)C(=O)CC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H23NO3/c1-11(2)8-14(17)15(18)10-13(16(19)20)9-12-6-4-3-5-7-12/h3-7,11,13-14H,8-10,17H2,1-2H3,(H,19,20)/t13?,14-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
770n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver; Ki value reporting the slope effect(Kis)


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Homo sapiens)
BDBM50008430
PNG
(3-Amino-N-(3-methyl-butyl)-2-oxo-4-phenyl-butyrami...)
Show SMILES CC(C)CCNC(=O)C(=O)C(N)Cc1ccccc1
Show InChI InChI=1S/C15H22N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13H,8-10,16H2,1-2H3,(H,17,19)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
1.50E+3n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Compound was tested for binding affinity towards arginyl aminopeptidase


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50017479
PNG
(2-(5,9-Diamino-2-methyl-4-oxo-nonanoylamino)-3-phe...)
Show SMILES CC(CC(=O)[C@@H](N)CCCCN)C(=O)NC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C19H29N3O4/c1-13(11-17(23)15(21)9-5-6-10-20)18(24)22-16(19(25)26)12-14-7-3-2-4-8-14/h2-4,7-8,13,15-16H,5-6,9-12,20-21H2,1H3,(H,22,24)(H,25,26)/t13?,15-,16?/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
2.00E+3n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Non-competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver; Ki value reporting the intercept effect(Kii)


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50017484
PNG
(5,9-Diamino-2-methyl-4-oxo-nonanoic acid | CHEMBL2...)
Show SMILES CC(CC(=O)[C@@H](N)CCCCN)C(O)=O
Show InChI InChI=1S/C10H20N2O3/c1-7(10(14)15)6-9(13)8(12)4-2-3-5-11/h7-8H,2-6,11-12H2,1H3,(H,14,15)/t7?,8-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
2.00E+3n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver; Ki value reporting the slope effect(Kis)


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50022747
PNG
(2-(3-Amino-2-hydroxy-4-phenyl-thiobutyrylamino)-4-...)
Show SMILES CC(C)C[C@H](NC(=S)[C@@H](O)[C@H](N)Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H24N2O3S/c1-10(2)8-13(16(20)21)18-15(22)14(19)12(17)9-11-6-4-3-5-7-11/h3-7,10,12-14,19H,8-9,17H2,1-2H3,(H,18,22)(H,20,21)/t12-,13+,14+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
2.40E+3n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50017479
PNG
(2-(5,9-Diamino-2-methyl-4-oxo-nonanoylamino)-3-phe...)
Show SMILES CC(CC(=O)[C@@H](N)CCCCN)C(=O)NC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C19H29N3O4/c1-13(11-17(23)15(21)9-5-6-10-20)18(24)22-16(19(25)26)12-14-7-3-2-4-8-14/h2-4,7-8,13,15-16H,5-6,9-12,20-21H2,1H3,(H,22,24)(H,25,26)/t13?,15-,16?/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
2.80E+3n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Non-competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver; Ki value reporting the Kid


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Homo sapiens)
BDBM50008433
PNG
(3-Amino-5-methyl-2-oxo-hexanoic acid (3-methyl-but...)
Show SMILES CC(C)CCNC(=O)C(=O)[C@@H](N)CC(C)C
Show InChI InChI=1S/C12H24N2O2/c1-8(2)5-6-14-12(16)11(15)10(13)7-9(3)4/h8-10H,5-7,13H2,1-4H3,(H,14,16)/t10-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
3.20E+3n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Compound was tested for binding affinity towards arginyl aminopeptidase


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50022744
PNG
(3-Amino-2-mercapto-N-(3-methyl-butyl)-4-phenyl-but...)
Show SMILES CC(C)CCNC(=O)[C@@H](S)[C@H](N)Cc1ccccc1
Show InChI InChI=1S/C15H24N2OS/c1-11(2)8-9-17-15(18)14(19)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,19H,8-10,16H2,1-2H3,(H,17,18)/t13-,14+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
4.00E+3n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Homo sapiens)
BDBM50008432
PNG
(3-Amino-5-methyl-2-oxo-hexanoic acid (3-methyl-but...)
Show SMILES CC(C)CCNC(=O)C(=O)[C@H](N)CC(C)C
Show InChI InChI=1S/C12H24N2O2/c1-8(2)5-6-14-12(16)11(15)10(13)7-9(3)4/h8-10H,5-7,13H2,1-4H3,(H,14,16)/t10-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
6.50E+3n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Compound was tested for binding affinity towards arginyl aminopeptidase


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50022745
PNG
(3-Amino-5-methyl-hexane-2-thiol | CHEMBL69814)
Show SMILES CC(C)C[C@H](N)C(C)S
Show InChI InChI=1S/C7H17NS/c1-5(2)4-7(8)6(3)9/h5-7,9H,4,8H2,1-3H3/t6?,7-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
7.00E+3n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50017479
PNG
(2-(5,9-Diamino-2-methyl-4-oxo-nonanoylamino)-3-phe...)
Show SMILES CC(CC(=O)[C@@H](N)CCCCN)C(=O)NC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C19H29N3O4/c1-13(11-17(23)15(21)9-5-6-10-20)18(24)22-16(19(25)26)12-14-7-3-2-4-8-14/h2-4,7-8,13,15-16H,5-6,9-12,20-21H2,1H3,(H,22,24)(H,25,26)/t13?,15-,16?/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
8.80E+3n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Non-competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver; Ki value reporting the slope effect(Kis)


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50022754
PNG
(3-Amino-2-mercapto-N-(3-methyl-butyl)-4-phenyl-but...)
Show SMILES CC(C)CCNC(=O)[C@H](S)[C@@H](N)Cc1ccccc1
Show InChI InChI=1S/C15H24N2OS/c1-11(2)8-9-17-15(18)14(19)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,19H,8-10,16H2,1-2H3,(H,17,18)/t13-,14+/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
3.57E+4n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50017483
PNG
(5-Amino-2-benzyl-7-methyl-4-oxo-octanoic acid [2-m...)
Show SMILES CC(C)CCNC(=O)[C@@H](NC(=O)[C@H](CC(=O)[C@@H](N)CC(C)C)Cc1ccccc1)C(C)C
Show InChI InChI=1S/C26H43N3O3/c1-17(2)12-13-28-26(32)24(19(5)6)29-25(31)21(15-20-10-8-7-9-11-20)16-23(30)22(27)14-18(3)4/h7-11,17-19,21-22,24H,12-16,27H2,1-6H3,(H,28,32)(H,29,31)/t21-,22-,24-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
3.60E+4n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver; Ki value reporting the slope effect(Kis)


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Homo sapiens)
BDBM50008431
PNG
(3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...)
Show SMILES CC(C)CCNC(=O)[C@@H](O)[C@H](N)Cc1ccccc1
Show InChI InChI=1S/C15H24N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,18H,8-10,16H2,1-2H3,(H,17,19)/t13-,14+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
3.90E+4n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Compound was tested for binding affinity towards arginyl aminopeptidase


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50008431
PNG
(3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-buty...)
Show SMILES CC(C)CCNC(=O)[C@@H](O)[C@H](N)Cc1ccccc1
Show InChI InChI=1S/C15H24N2O2/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,18H,8-10,16H2,1-2H3,(H,17,19)/t13-,14+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
3.90E+4n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50022746
PNG
(2,6-Diamino-hexan-1-ol | CHEMBL69146)
Show SMILES NCCCC[C@@H](N)CO
Show InChI InChI=1S/C6H16N2O/c7-4-2-1-3-6(8)5-9/h6,9H,1-5,7-8H2/t6-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
1.00E+5n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50017473
PNG
(5-Amino-2,7-dimethyl-4-oxo-octanoic acid | CHEMBL2...)
Show SMILES CC(C)CC(N)C(=O)CC(C)C(O)=O
Show InChI InChI=1S/C10H19NO3/c1-6(2)4-8(11)9(12)5-7(3)10(13)14/h6-8H,4-5,11H2,1-3H3,(H,13,14)
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
1.30E+5n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Competitive inhibition of aminopeptidase B or arginyl aminopeptidase purified from rat liver; Ki value reporting the slope effect(Kis)


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Homo sapiens)
BDBM50008427
PNG
(5-Amino-2,7-dimethyl-4-oxo-octanoic acid | CHEMBL3...)
Show SMILES CC(C)C[C@H](N)C(=O)CC(C)C(O)=O
Show InChI InChI=1S/C10H19NO3/c1-6(2)4-8(11)9(12)5-7(3)10(13)14/h6-8H,4-5,11H2,1-3H3,(H,13,14)/t7?,8-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
1.30E+5n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Compound was tested for binding affinity towards arginyl aminopeptidase


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50022752
PNG
((R)-3-Amino-2-mercapto-4-phenyl-butyric acid methy...)
Show SMILES COC(=O)C(S)[C@H](N)Cc1ccccc1
Show InChI InChI=1S/C11H15NO2S/c1-14-11(13)10(15)9(12)7-8-5-3-2-4-6-8/h2-6,9-10,15H,7,12H2,1H3/t9-,10?/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
1.59E+5n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50022753
PNG
(3-Amino-5-methyl-hexan-2-ol | CHEMBL68511)
Show SMILES CC(C)C[C@H](N)C(C)O
Show InChI InChI=1S/C7H17NO/c1-5(2)4-7(8)6(3)9/h5-7,9H,4,8H2,1-3H3/t6?,7-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
>2.00E+5n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Homo sapiens)
BDBM50008428
PNG
(3-Amino-2-hydroxy-5-methyl-hexanoic acid (3-methyl...)
Show SMILES CC(C)CCNC(=O)[C@@H](O)[C@H](N)CC(C)C
Show InChI InChI=1S/C12H26N2O2/c1-8(2)5-6-14-12(16)11(15)10(13)7-9(3)4/h8-11,15H,5-7,13H2,1-4H3,(H,14,16)/t10-,11+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
>3.00E+5n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Compound was tested for binding affinity towards arginyl aminopeptidase


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50022750
PNG
(3-Amino-2-hydroxy-4-phenyl-butyric acid methyl est...)
Show SMILES COC(=O)C(O)[C@H](N)Cc1ccccc1
Show InChI InChI=1S/C11H15NO3/c1-15-11(14)10(13)9(12)7-8-5-3-2-4-6-8/h2-6,9-10,13H,7,12H2,1H3/t9-,10?/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

PubMed
>1.00E+6n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50022749
PNG
(2-Amino-4-methyl-pentan-1-ol | CHEMBL71171 | D-Leu...)
Show SMILES CC(C)C[C@@H](N)CO
Show InChI InChI=1S/C6H15NO/c1-5(2)3-6(7)4-8/h5-6,8H,3-4,7H2,1-2H3/t6-/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
>1.00E+6n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Homo sapiens)
BDBM50008429
PNG
((3S)-3-amino-5-methylhexan-2-one | 3-Amino-5-methy...)
Show SMILES CC(C)C[C@H](N)C(C)=O
Show InChI InChI=1S/C7H15NO/c1-5(2)4-7(8)6(3)9/h5,7H,4,8H2,1-3H3/t7-/m0/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

PubMed
>1.00E+6n/an/an/an/an/an/an/an/a



University of Wisconsin-Madison

Curated by ChEMBL


Assay Description
Compound was tested for binding affinity towards arginyl aminopeptidase


Citation and Details
More data for this
Ligand-Target Pair
Aminopeptidase B


(Rattus norvegicus)
BDBM50022742
PNG
(3-Amino-2-hydroxy-N-(3-methyl-butyl)-4-phenyl-thio...)
Show SMILES CC(C)CCNC(=S)[C@@H](O)[C@H](N)Cc1ccccc1
Show InChI InChI=1S/C15H24N2OS/c1-11(2)8-9-17-15(19)14(18)13(16)10-12-6-4-3-5-7-12/h3-7,11,13-14,18H,8-10,16H2,1-2H3,(H,17,19)/t13-,14+/m1/s1
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
PubMed
>1.00E+6n/an/an/an/an/an/an/an/a



University of Wisconsin

Curated by ChEMBL


Assay Description
Inhibitory activity against aminopeptidase B


Citation and Details
More data for this
Ligand-Target Pair