BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 26 hits of ki data for polymerid = 50000643   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133948
PNG
((S)-2-[(3aS,6S,6aR)-4-(6-Hydroxymethyl-benzothiazo...)
Show SMILES CC(C)c1ccc(NC(=O)N2CCC[C@H]2C(=O)N2CC[C@H]3[C@H]2[C@H](C)C(=O)N3c2nc3ccc(CO)cc3s2)cc1
Show InChI InChI=1S/C30H35N5O4S/c1-17(2)20-7-9-21(10-8-20)31-29(39)33-13-4-5-24(33)28(38)34-14-12-23-26(34)18(3)27(37)35(23)30-32-22-11-6-19(16-36)15-25(22)40-30/h6-11,15,17-18,23-24,26,36H,4-5,12-14,16H2,1-3H3,(H,31,39)/t18-,23-,24-,26+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
0.310n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133962
PNG
((3S,3aR,6aS)-4-({(2S)-1-[(5-Chloro-3-methyl-1-benz...)
Show SMILES C[C@H]1[C@@H]2[C@H](CCN2C(=O)[C@@H]2CCCN2C(=O)c2sc3ccc(Cl)cc3c2C)N(C(=O)C2CC2)C1=O
Show InChI InChI=1S/C26H28ClN3O4S/c1-13-17-12-16(27)7-8-20(17)35-22(13)26(34)28-10-3-4-19(28)25(33)29-11-9-18-21(29)14(2)23(31)30(18)24(32)15-5-6-15/h7-8,12,14-15,18-19,21H,3-6,9-11H2,1-2H3/t14-,18-,19-,21+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
2n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133960
PNG
((S)-2-((3aS,6S,6aR)-4-Cyclopropanecarbonyl-6-methy...)
Show SMILES CC(C)c1ccc(NC(=O)N2CCC[C@H]2C(=O)N2CC[C@H]3[C@H]2[C@H](C)C(=O)N3C(=O)C2CC2)cc1
Show InChI InChI=1S/C26H34N4O4/c1-15(2)17-8-10-19(11-9-17)27-26(34)28-13-4-5-21(28)25(33)29-14-12-20-22(29)16(3)23(31)30(20)24(32)18-6-7-18/h8-11,15-16,18,20-22H,4-7,12-14H2,1-3H3,(H,27,34)/t16-,20-,21-,22+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
2n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133951
PNG
(2-{(3S,3aR,6aS)-4-[(S)-1-(4-Isopropyl-phenylcarbam...)
Show SMILES CCOC(=O)c1ccc2nc(sc2c1)N1[C@H]2CCN([C@@H]2[C@H](C)C1=O)C(=O)[C@@H]1CCCN1C(=O)Nc1ccc(cc1)C(C)C
Show InChI InChI=1S/C32H37N5O5S/c1-5-42-30(40)21-10-13-23-26(17-21)43-32(34-23)37-24-14-16-36(27(24)19(4)28(37)38)29(39)25-7-6-15-35(25)31(41)33-22-11-8-20(9-12-22)18(2)3/h8-13,17-19,24-25,27H,5-7,14-16H2,1-4H3,(H,33,41)/t19-,24-,25-,27+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
7.40n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133989
PNG
((S)-2-((3aS,6S,6aR)-4-Cyclopropanecarbonyl-6-methy...)
Show SMILES CCCOc1ccc(cc1)-c1ccc(NC(=O)N2CCC[C@H]2C(=O)N2CC[C@H]3[C@H]2[C@H](C)C(=O)N3C(=O)C2CC2)cc1
Show InChI InChI=1S/C32H38N4O5/c1-3-19-41-25-14-10-22(11-15-25)21-8-12-24(13-9-21)33-32(40)34-17-4-5-27(34)31(39)35-18-16-26-28(35)20(2)29(37)36(26)30(38)23-6-7-23/h8-15,20,23,26-28H,3-7,16-19H2,1-2H3,(H,33,40)/t20-,26-,27-,28+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
9n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133981
PNG
((2S)-2-{[(3aS,6S,6aR)-4-(Cyclopropylcarbonyl)-6-me...)
Show SMILES CCCOc1ccc(NC(=O)N2CCC[C@H]2C(=O)N2CC[C@H]3[C@H]2[C@H](C)C(=O)N3C(=O)C2CC2)cc1
Show InChI InChI=1S/C26H34N4O5/c1-3-15-35-19-10-8-18(9-11-19)27-26(34)28-13-4-5-21(28)25(33)29-14-12-20-22(29)16(2)23(31)30(20)24(32)17-6-7-17/h8-11,16-17,20-22H,3-7,12-15H2,1-2H3,(H,27,34)/t16-,20-,21-,22+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
9n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133952
PNG
((S)-2-((3aS,6S,6aR)-4-Benzothiazol-2-yl-6-methyl-5...)
Show SMILES CC(C)c1ccc(NC(=O)N2CCC[C@H]2C(=O)N2CC[C@H]3[C@H]2[C@H](C)C(=O)N3c2nc3ccccc3s2)cc1
Show InChI InChI=1S/C29H33N5O3S/c1-17(2)19-10-12-20(13-11-19)30-28(37)32-15-6-8-23(32)27(36)33-16-14-22-25(33)18(3)26(35)34(22)29-31-21-7-4-5-9-24(21)38-29/h4-5,7,9-13,17-18,22-23,25H,6,8,14-16H2,1-3H3,(H,30,37)/t18-,22-,23-,25+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
10n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133969
PNG
((S)-2-((3aS,6S,6aR)-4-Cyclopropanecarbonyl-6-methy...)
Show SMILES C[C@H]1[C@@H]2[C@H](CCN2C(=O)[C@@H]2CCCN2C(=O)Nc2ccc(cc2)C(F)(F)F)N(C(=O)C2CC2)C1=O
Show InChI InChI=1S/C24H27F3N4O4/c1-13-19-17(31(20(13)32)21(33)14-4-5-14)10-12-30(19)22(34)18-3-2-11-29(18)23(35)28-16-8-6-15(7-9-16)24(25,26)27/h6-9,13-14,17-19H,2-5,10-12H2,1H3,(H,28,35)/t13-,17-,18-,19+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
15n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133957
PNG
((S)-2-[(3aS,6S,6aR)-6-Methyl-4-((2R,3S)-2-(S)-meth...)
Show SMILES CC(C)c1ccc(NC(=O)N2CCC[C@H]2C(=O)N2CC[C@H]3[C@H]2[C@H](C)C(=O)N3C(=O)[C@H]2[C@@H](C)[C@H]2C)cc1
Show InChI InChI=1S/C28H38N4O4/c1-15(2)19-8-10-20(11-9-19)29-28(36)30-13-6-7-22(30)26(34)31-14-12-21-24(31)18(5)25(33)32(21)27(35)23-16(3)17(23)4/h8-11,15-18,21-24H,6-7,12-14H2,1-5H3,(H,29,36)/t16-,17+,18-,21-,22-,23-,24+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
16n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133980
PNG
((2S)-2-{[(3aS,6S,6aR)-4-(Cyclopropylcarbonyl)-6-me...)
Show SMILES CC(C)Oc1ccc(NC(=O)N2CCC[C@H]2C(=O)N2CC[C@H]3[C@H]2[C@H](C)C(=O)N3C(=O)C2CC2)cc1
Show InChI InChI=1S/C26H34N4O5/c1-15(2)35-19-10-8-18(9-11-19)27-26(34)28-13-4-5-21(28)25(33)29-14-12-20-22(29)16(3)23(31)30(20)24(32)17-6-7-17/h8-11,15-17,20-22H,4-7,12-14H2,1-3H3,(H,27,34)/t16-,20-,21-,22+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
18n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133950
PNG
((S)-2-[(3aS,6S,6aR)-6-Methyl-5-oxo-4-(6-trifluorom...)
Show SMILES CC(C)c1ccc(NC(=O)N2CCC[C@H]2C(=O)N2CC[C@H]3[C@H]2[C@H](C)C(=O)N3c2nc3ccc(OC(F)(F)F)cc3s2)cc1
Show InChI InChI=1S/C30H32F3N5O4S/c1-16(2)18-6-8-19(9-7-18)34-28(41)36-13-4-5-23(36)27(40)37-14-12-22-25(37)17(3)26(39)38(22)29-35-21-11-10-20(15-24(21)43-29)42-30(31,32)33/h6-11,15-17,22-23,25H,4-5,12-14H2,1-3H3,(H,34,41)/t17-,22-,23-,25+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
20n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50107904
PNG
((3S,3aR,6aS)-1-Cyclopropanecarbonyl-4-[(S)-1-(5-di...)
Show SMILES C[C@H]1[C@@H]2[C@H](CCN2C(=O)[C@@H]2CCCN2S(=O)(=O)c2cccc3c(cccc23)N(C)C)N(C(=O)C2CC2)C1=O
Show InChI InChI=1S/C28H34N4O5S/c1-17-25-22(32(26(17)33)27(34)18-12-13-18)14-16-30(25)28(35)23-10-6-15-31(23)38(36,37)24-11-5-7-19-20(24)8-4-9-21(19)29(2)3/h4-5,7-9,11,17-18,22-23,25H,6,10,12-16H2,1-3H3/t17-,22-,23-,25+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
20n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133992
PNG
((3S,3aR,6aS)-4-[(S)-1-(Biphenyl-4-carbonyl)-pyrrol...)
Show SMILES C[C@H]1[C@@H]2[C@H](CCN2C(=O)[C@@H]2CCCN2C(=O)c2ccc(cc2)-c2ccccc2)N(C(=O)C2CC2)C1=O
Show InChI InChI=1S/C29H31N3O4/c1-18-25-23(32(26(18)33)28(35)22-13-14-22)15-17-31(25)29(36)24-8-5-16-30(24)27(34)21-11-9-20(10-12-21)19-6-3-2-4-7-19/h2-4,6-7,9-12,18,22-25H,5,8,13-17H2,1H3/t18-,23-,24-,25+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
21n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133953
PNG
((S)-2-((3aS,6S,6aR)-6-Methyl-5-oxo-4-thiazolo[5,4-...)
Show SMILES CC(C)c1ccc(NC(=O)N2CCC[C@H]2C(=O)N2CC[C@H]3[C@H]2[C@H](C)C(=O)N3c2nc3cccnc3s2)cc1
Show InChI InChI=1S/C28H32N6O3S/c1-16(2)18-8-10-19(11-9-18)30-27(37)32-14-5-7-22(32)26(36)33-15-12-21-23(33)17(3)25(35)34(21)28-31-20-6-4-13-29-24(20)38-28/h4,6,8-11,13,16-17,21-23H,5,7,12,14-15H2,1-3H3,(H,30,37)/t17-,21-,22-,23+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
21n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133975
PNG
((S)-2-[(3aS,6S,6aR)-6-Methyl-4-(6-nitro-benzothiaz...)
Show SMILES CC(C)c1ccc(NC(=O)N2CCC[C@H]2C(=O)N2CC[C@H]3[C@H]2[C@H](C)C(=O)N3c2nc3ccc(cc3s2)[N+]([O-])=O)cc1
Show InChI InChI=1S/C29H32N6O5S/c1-16(2)18-6-8-19(9-7-18)30-28(38)32-13-4-5-23(32)27(37)33-14-12-22-25(33)17(3)26(36)34(22)29-31-21-11-10-20(35(39)40)15-24(21)41-29/h6-11,15-17,22-23,25H,4-5,12-14H2,1-3H3,(H,30,38)/t17-,22-,23-,25+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
25n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133978
PNG
((3S,3aR,6aS)-1-Cyclopropanecarbonyl-3-methyl-4-[(S...)
Show SMILES CCCOc1ccc(cc1)-c1ccc(cc1)S(=O)(=O)N1CCC[C@H]1C(=O)N1CC[C@H]2[C@H]1[C@H](C)C(=O)N2C(=O)C1CC1
Show InChI InChI=1S/C31H37N3O6S/c1-3-19-40-24-12-8-21(9-13-24)22-10-14-25(15-11-22)41(38,39)33-17-4-5-27(33)31(37)32-18-16-26-28(32)20(2)29(35)34(26)30(36)23-6-7-23/h8-15,20,23,26-28H,3-7,16-19H2,1-2H3/t20-,26-,27-,28+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
33n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133964
PNG
((3S,3aR,6aS)-1-Cyclopropanecarbonyl-3-methyl-4-[(S...)
Show SMILES CCCOc1ccc(cc1)S(=O)(=O)N1CCC[C@H]1C(=O)N1CC[C@H]2[C@H]1[C@H](C)C(=O)N2C(=O)C1CC1
Show InChI InChI=1S/C25H33N3O6S/c1-3-15-34-18-8-10-19(11-9-18)35(32,33)27-13-4-5-21(27)25(31)26-14-12-20-22(26)16(2)23(29)28(20)24(30)17-6-7-17/h8-11,16-17,20-22H,3-7,12-15H2,1-2H3/t16-,20-,21-,22+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
33n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133977
PNG
((2S)-2-{[(3aS,6S,6aR)-4-(Cyclopropylcarbonyl)-6-me...)
Show SMILES C[C@H]1[C@@H]2[C@H](CCN2C(=O)[C@@H]2CCCN2C(=O)Nc2ccc(Cl)cc2)N(C(=O)C2CC2)C1=O
Show InChI InChI=1S/C23H27ClN4O4/c1-13-19-17(28(20(13)29)21(30)14-4-5-14)10-12-27(19)22(31)18-3-2-11-26(18)23(32)25-16-8-6-15(24)7-9-16/h6-9,13-14,17-19H,2-5,10-12H2,1H3,(H,25,32)/t13-,17-,18-,19+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
38n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133979
PNG
((3S,3aR,6aS)-1-Cyclopropanecarbonyl-4-[(S)-1-(4-is...)
Show SMILES CC(C)Oc1ccc(cc1)S(=O)(=O)N1CCC[C@H]1C(=O)N1CC[C@H]2[C@H]1[C@H](C)C(=O)N2C(=O)C1CC1
Show InChI InChI=1S/C25H33N3O6S/c1-15(2)34-18-8-10-19(11-9-18)35(32,33)27-13-4-5-21(27)25(31)26-14-12-20-22(26)16(3)23(29)28(20)24(30)17-6-7-17/h8-11,15-17,20-22H,4-7,12-14H2,1-3H3/t16-,20-,21-,22+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
39n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133988
PNG
((3S,3aR,6aS)-1-(Cyclopropylcarbonyl)-3-methyl-4-{[...)
Show SMILES C[C@H]1[C@@H]2[C@H](CCN2C(=O)[C@@H]2CCCN2S(=O)(=O)c2ccc3ccccc3c2)N(C(=O)C2CC2)C1=O
Show InChI InChI=1S/C26H29N3O5S/c1-16-23-21(29(24(16)30)25(31)18-8-9-18)12-14-27(23)26(32)22-7-4-13-28(22)35(33,34)20-11-10-17-5-2-3-6-19(17)15-20/h2-3,5-6,10-11,15-16,18,21-23H,4,7-9,12-14H2,1H3/t16-,21-,22-,23+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
40n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133985
PNG
((S)-2-[(3aS,6S,6aR)-4-(6-Methoxy-benzothiazol-2-yl...)
Show SMILES COc1ccc2nc(sc2c1)N1[C@H]2CCN([C@@H]2[C@H](C)C1=O)C(=O)[C@@H]1CCCN1C(=O)Nc1ccc(cc1)C(C)C
Show InChI InChI=1S/C30H35N5O4S/c1-17(2)19-7-9-20(10-8-19)31-29(38)33-14-5-6-24(33)28(37)34-15-13-23-26(34)18(3)27(36)35(23)30-32-22-12-11-21(39-4)16-25(22)40-30/h7-12,16-18,23-24,26H,5-6,13-15H2,1-4H3,(H,31,38)/t18-,23-,24-,26+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
43n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133949
PNG
((3S,3aR,6aS)-1-Cyclopropanecarbonyl-3-methyl-4-[(S...)
Show SMILES C[C@H]1[C@@H]2[C@H](CCN2C(=O)[C@@H]2CCCN2S(=O)(=O)c2cccc3ccccc23)N(C(=O)C2CC2)C1=O
Show InChI InChI=1S/C26H29N3O5S/c1-16-23-20(29(24(16)30)25(31)18-11-12-18)13-15-27(23)26(32)21-9-5-14-28(21)35(33,34)22-10-4-7-17-6-2-3-8-19(17)22/h2-4,6-8,10,16,18,20-21,23H,5,9,11-15H2,1H3/t16-,20-,21-,23+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
60n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133991
PNG
((3S,3aR,6aS)-1-Cyclopropanecarbonyl-3-methyl-4-[(S...)
Show SMILES CCCOc1ccc(cc1)-c1ccc(cc1)C(=O)N1CCC[C@H]1C(=O)N1CC[C@H]2[C@H]1[C@H](C)C(=O)N2C(=O)C1CC1
Show InChI InChI=1S/C32H37N3O5/c1-3-19-40-25-14-12-22(13-15-25)21-6-8-23(9-7-21)30(37)33-17-4-5-27(33)32(39)34-18-16-26-28(34)20(2)29(36)35(26)31(38)24-10-11-24/h6-9,12-15,20,24,26-28H,3-5,10-11,16-19H2,1-2H3/t20-,26-,27-,28+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
79n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133954
PNG
((3S,3aR,6aS)-1-Cyclopropanecarbonyl-3-methyl-4-[(S...)
Show SMILES CCCOc1ccc(cc1)C(=O)N1CCC[C@H]1C(=O)N1CC[C@H]2[C@H]1[C@H](C)C(=O)N2C(=O)C1CC1
Show InChI InChI=1S/C26H33N3O5/c1-3-15-34-19-10-8-17(9-11-19)24(31)27-13-4-5-21(27)26(33)28-14-12-20-22(28)16(2)23(30)29(20)25(32)18-6-7-18/h8-11,16,18,20-22H,3-7,12-15H2,1-2H3/t16-,20-,21-,22+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
79n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133987
PNG
((3S,3aR,6aS)-1-Cyclopropanecarbonyl-4-[(S)-1-(4-is...)
Show SMILES CC(C)c1ccc(cc1)S(=O)(=O)N1CCC[C@H]1C(=O)N1CC[C@H]2[C@H]1[C@H](C)C(=O)N2C(=O)C1CC1
Show InChI InChI=1S/C25H33N3O5S/c1-15(2)17-8-10-19(11-9-17)34(32,33)27-13-4-5-21(27)25(31)26-14-12-20-22(26)16(3)23(29)28(20)24(30)18-6-7-18/h8-11,15-16,18,20-22H,4-7,12-14H2,1-3H3/t16-,20-,21-,22+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
99n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair
Human herpes virus 5 capsid protein P40


(Human cytomegalovirus (strain AD169) (HHV-5) (Huma...)
BDBM50133967
PNG
((S)-2-((3aS,6S,6aR)-6-Methyl-5-oxo-4-thiazol-2-yl-...)
Show SMILES CC(C)c1ccc(NC(=O)N2CCC[C@H]2C(=O)N2CC[C@H]3[C@H]2[C@H](C)C(=O)N3c2nccs2)cc1
Show InChI InChI=1S/C25H31N5O3S/c1-15(2)17-6-8-18(9-7-17)27-24(33)28-12-4-5-20(28)23(32)29-13-10-19-21(29)16(3)22(31)30(19)25-26-11-14-34-25/h6-9,11,14-16,19-21H,4-5,10,12-13H2,1-3H3,(H,27,33)/t16-,19-,20-,21+/m0/s1
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
446n/an/an/an/an/an/an/an/a



GlaxoSmithKline Research and Development

Curated by ChEMBL


Assay Description
Potency against human cytomegalovirus protease in HCMV pNA assay


J Med Chem 46: 4428-49 (2003)

More data for this
Ligand-Target Pair