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Found 7 of ec50 for UniProtKB: P09810
TargetTryptophan 5-hydroxylase 1(Rattus norvegicus)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243618((2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(2...)
Affinity DataEC50:  48nMAssay Description:Inhibition of TPH1 in RBL cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 5-hydroxylase 1(Rattus norvegicus)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243617((S)-2-Amino-3-(4-{2-amino-6-[2,2,2-trifluoro-1-(3'...)
Affinity DataEC50:  56nMAssay Description:Inhibition of TPH1 in RBL cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 5-hydroxylase 1(Rattus norvegicus)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243655((2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(3...)
Affinity DataEC50:  63nMAssay Description:Inhibition of TPH1 in RBL cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 5-hydroxylase 1(Rattus norvegicus)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243619((S) -2-amino-3-[4-(2-amino-6-[2,2,2-trifluoro-1-(2...)
Affinity DataEC50:  70nMAssay Description:Inhibition of TPH1 in RBL cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 5-hydroxylase 1(Rattus norvegicus)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243024((2S)-2-amino-3-(4-(2-amino-6-(2,2,2-trifluoro-1-(n...)
Affinity DataEC50:  510nMAssay Description:Inhibition of TPH1 in RBL cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 5-hydroxylase 1(Rattus norvegicus)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243022((S)-2-amino-3-(4-(2-amino-6-((R)-1-(naphthalen-2-y...)
Affinity DataEC50:  1.70E+3nMAssay Description:Inhibition of TPH1 in RBL cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTryptophan 5-hydroxylase 1(Rattus norvegicus)
Lexicon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50243023((S)-2-amino-3-(4-(2-amino-6-((R)-1-(naphthalen-2-y...)
Affinity DataEC50:  1.10E+4nMAssay Description:Inhibition of TPH1 in RBL cells assessed as inhibition of serotonin biosynthesisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed