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Found 6 of ic50 for UniProtKB: P18298
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
Laboratoire De Chimie Bioorganique

LigandPNGBDBM85447(Epoxy analogue, I(a))
Affinity DataKi:  7.00E+3nM ΔG°:  -7.31kcal/mole IC50:  5.00E+4nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
Laboratoire De Chimie Bioorganique

LigandPNGBDBM85448(Epoxy analogue, I(b))
Affinity DataKi:  6.10E+4nM ΔG°:  -5.98kcal/mole IC50:  1.00E+5nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
Laboratoire De Chimie Bioorganique

LigandPNGBDBM85449(Epoxy analogue, I(c))
Affinity DataKi:  1.05E+5nM ΔG°:  -5.64kcal/mole IC50:  1.10E+5nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
Laboratoire De Chimie Bioorganique

LigandPNGBDBM85450(Epithioamino acid analogue, II(a))
Affinity DataKi:  1.00E+5nM ΔG°:  -5.67kcal/mole IC50:  1.40E+5nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
Laboratoire De Chimie Bioorganique

LigandPNGBDBM85451(Epithioamino acid analogue, II(b))
Affinity DataKi:  1.40E+5nM ΔG°:  -5.47kcal/mole IC50:  3.00E+5nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
Laboratoire De Chimie Bioorganique

LigandPNGBDBM85452(Epithioamino acid analogue, II(c))
Affinity DataKi:  1.40E+5nM ΔG°:  -5.47kcal/mole IC50:  4.00E+5nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed