Compile Data Set for Download or QSAR
maximum 50k data
Found 107 of ki for UniProtKB: P18298
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50228186(CHEMBL3706404)
Affinity DataKi:  110nMAssay Description:Compound was tested for inhibition constant with kidney form of M-2 variants of Rat methionine adenosyltransferase when ATP was the variable substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50227269(CHEMBL3706402)
Affinity DataKi:  130nMAssay Description:Inhibition constant of ATP varied compound was measured on M-2 variate Methionine adenosyltransferase in rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50226974(CHEMBL603986)
Affinity DataKi:  130nMAssay Description:Inhibition constants of M-2 Forms of rat methionine adenosyltransferase using ATP as the variable substrate; Inhibition is competitive typeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50227269(CHEMBL3706402)
Affinity DataKi:  130nMAssay Description:Compound was tested for inhibition constant with kidney form of M-2 variants of Rat methionine adenosyltransferase when ATP was the variable substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50228186(CHEMBL3706404)
Affinity DataKi:  160nMAssay Description:Compound was tested for inhibition constant with kidney form of M-T variants of Rat methionine adenosyltransferase when ATP was the variable substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50227269(CHEMBL3706402)
Affinity DataKi:  210nMAssay Description:Compound was tested for inhibition constant with kidney form of M-T variants of Rat methionine adenosyltransferase when ATP was the variable substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50226974(CHEMBL603986)
Affinity DataKi:  210nMAssay Description:Inhibition constants of MT Forms of rat Novikoff Ascitic Hepatomae using ATP as the variable substrate; Inhibition is competitive typeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50227269(CHEMBL3706402)
Affinity DataKi:  210nMAssay Description:Inhibition constant of ATP varied compound was measured on MT variant methionine adenosyltransferase in rat ascitic hepatoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50226770(CHEMBL609078)
Affinity DataKi:  270nMAssay Description:Inhibition constant of compound with Novikoff ascitic hepatoma (M-T) form of rat methionine adenosyltransferase when ATP was used as variable substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50228185(CHEMBL3706405)
Affinity DataKi:  270nMAssay Description:Compound was tested for inhibition constant with kidney form of M-2 variants of Rat methionine adenosyltransferase when ATP was the variable substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50226972(CHEMBL606493)
Affinity DataKi:  270nMAssay Description:Inhibition constants of MT Forms of rat Novikoff Ascitic Hepatomae using ATP as the variable substrate; Inhibition is competitive typeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50226768(CHEMBL1791426)
Affinity DataKi:  270nMAssay Description:Inhibition constant of ATP varied compound was measured on MT variant methionine adenosyltransferase in rat ascitic hepatoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50226972(CHEMBL606493)
Affinity DataKi:  360nMAssay Description:Inhibition constants of M-2 Forms of rat methionine adenosyltransferase using ATP as the variable substrate; Inhibition is competitive typeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50226770(CHEMBL609078)
Affinity DataKi:  360nMAssay Description:Inhibition constant of compound with kidney (M-2) form of rat methionine adenosyltransferase when ATP was used as variable substrate;Competitive type...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50226768(CHEMBL1791426)
Affinity DataKi:  360nMAssay Description:Inhibition constant of ATP varied compound was measured on M-2 variate methionine adenosyltransferase in rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50227270(CHEMBL3706403)
Affinity DataKi:  390nMAssay Description:Inhibition constant of ATP varied compound was measured on M-2 variate methionine adenosyltransferase in rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50228185(CHEMBL3706405)
Affinity DataKi:  410nMAssay Description:Compound was tested for inhibition constant with kidney form of M-T variants of Rat methionine adenosyltransferase when ATP was the variable substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50227271(CHEMBL1791425)
Affinity DataKi:  440nMAssay Description:Inhibition constant of ATP varied compound was measured on M-2 variate methionine adenosyltransferase in rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50227270(CHEMBL3706403)
Affinity DataKi:  630nMAssay Description:Inhibition constant of ATP varied compound was measured on MT variant methionine adenosyltransferase in rat ascitic hepatoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50227269(CHEMBL3706402)
Affinity DataKi:  650nMAssay Description:Inhibition constant of Met varied compound was measured on M-2 variant Methionine adenosyltransferase in rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50227269(CHEMBL3706402)
Affinity DataKi:  650nMAssay Description:Compound was tested for inhibition constant with kidney form of M-2 variants of Rat methionine adenosyltransferase when Methionine was the variable s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50226974(CHEMBL603986)
Affinity DataKi:  650nMAssay Description:Inhibition constants of M-2 Forms of rat methionine adenosyltransferase using Methionine as the variable substrate; Inhibition is non competitive typ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50227269(CHEMBL3706402)
Affinity DataKi:  670nMAssay Description:Inhibition constant of Met varied compound was measured on MT variant methionine adenosyltransferase in rat ascitic hepatoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50227269(CHEMBL3706402)
Affinity DataKi:  670nMAssay Description:Compound was tested for inhibition constant with kidney form of M-T variants of Rat methionine adenosyltransferase when Methionine was the variable s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50226974(CHEMBL603986)
Affinity DataKi:  670nMAssay Description:Inhibition constants of MT Forms of rat Novikoff Ascitic Hepatomae using Methionine as the variable substrate; Inhibition is non competitive typeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50227271(CHEMBL1791425)
Affinity DataKi:  810nMAssay Description:Inhibition constant of ATP varied compound was measured on MT variant methionine adenosyltransferase in rat ascitic hepatoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50228186(CHEMBL3706404)
Affinity DataKi:  1.10E+3nMAssay Description:Compound was tested for inhibition constant with kidney form of M-T variants of Rat methionine adenosyltransferase when Methionine was the variable s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50227271(CHEMBL1791425)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition constant of Met varied compound was measured on MT variant methionine adenosyltransferase in rat ascitic hepatoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50227271(CHEMBL1791425)
Affinity DataKi:  2.10E+3nMAssay Description:Inhibition constant of Met varied compound was measured on M-2 variant methionine adenosyltransferase in rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50228186(CHEMBL3706404)
Affinity DataKi:  2.10E+3nMAssay Description:Compound was tested for inhibition constant with kidney form of M-2 variants of Rat methionine adenosyltransferase when Methionine was the variable s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50227270(CHEMBL3706403)
Affinity DataKi:  2.20E+3nMAssay Description:Inhibition constant of Met varied compound was measured on M-2 variant methionine adenosyltransferase in rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50226768(CHEMBL1791426)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition constant of Met varied compound was measured on MT variant methionine adenosyltransferase in rat ascitic hepatoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50226770(CHEMBL609078)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition constant of compound with Novikoff ascitic hepatoma (M-T) form of rat methionine adenosyltransferase when methionine was used as variable ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50226972(CHEMBL606493)
Affinity DataKi:  2.30E+3nMAssay Description:Inhibition constants of MT Forms of rat Novikoff Ascitic Hepatomae using Methionine as the variable substrate; Inhibition is non competitive typeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50227270(CHEMBL3706403)
Affinity DataKi:  2.70E+3nMAssay Description:Inhibition constant of Met varied compound was measured on MT variant methionine adenosyltransferase in rat ascitic hepatoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50228185(CHEMBL3706405)
Affinity DataKi:  2.70E+3nMAssay Description:Compound was tested for inhibition constant with kidney form of M-T variants of Rat methionine adenosyltransferase when Methionine was the variable s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50226770(CHEMBL609078)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition constant of compound with kidney (M-2) form of rat methionine adenosyltransferase when methionine was used as variable substrate;Simple no...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50226972(CHEMBL606493)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition constants of M-2 Forms of rat methionine adenosyltransferase using Methionine as the variable substrate; Inhibition is non competitive typ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50226768(CHEMBL1791426)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition constant of Met varied compound was measured on M-2 variant methionine adenosyltransferase in rat kidneyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM18134(({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-...)
Affinity DataKi:  4.00E+3nMAssay Description:Inhibitory constant against rat Methionine adenosyltransferase was reportedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50228185(CHEMBL3706405)
Affinity DataKi:  5.40E+3nMAssay Description:Compound was tested for inhibition constant with kidney form of M-2 variants of Rat methionine adenosyltransferase when Methionine was the variable s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM18134(({[({[(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-...)
Affinity DataKi:  5.50E+3nMAssay Description:Inhibitory constant against rat kidney Methionine adenosyltransferase IIMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM85447(Epoxy analogue, I(a))
Affinity DataKi:  7.00E+3nM ΔG°:  -7.31kcal/mole IC50:  5.00E+4nMpH: 7.5 T: 2°CAssay Description:AdoMet synthetase activity was measured by a radioactive assay using (14C-methyl)-L-methionine as described by Sullivan and Hoffman with minor modifi...More data for this Ligand-Target Pair
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50367328(CHEMBL1791415)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition constant was evaluated on novikoff hepatoma (MAT-T) form of rat methionine adenosyltransferase, when ATP was the variable substrate (60 uM...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50226973(CHEMBL1791411)
Affinity DataKi:  1.10E+4nMAssay Description:Inhibition constants of MT Forms of rat Novikoff Ascitic Hepatomae using ATP as the variable substrate; Inhibition is competitive typeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50226769(CHEMBL607665)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition constant of compound with kidney (M-2) form of rat methionine adenosyltransferase when ATP was used as variable substrate;Competitive type...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50226973(CHEMBL1791411)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition constants of M-2 Forms of rat methionine adenosyltransferase using ATP as the variable substrate; Inhibition is competitive typeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-2(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50367328(CHEMBL1791415)
Affinity DataKi:  1.60E+4nMAssay Description:Inhibition constant was evaluated with kidney Methionine adenosyltransferase II form of rat methionine adenosyltransferase, when ATP was the variable...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50226768(CHEMBL1791426)
Affinity DataKi:  2.00E+4nMAssay Description:Inhibition constant of compound with Novikoff ascitic hepatoma (M-T) form of rat methionine adenosyltransferase when ATP was used as variable substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetS-adenosylmethionine synthase isoform type-1/type-2(Rattus norvegicus)
Fox Chase Cancer Center

Curated by ChEMBL
LigandPNGBDBM50226973(CHEMBL1791411)
Affinity DataKi:  2.60E+4nMAssay Description:Inhibition constants of M-2 Forms of rat methionine adenosyltransferase using Methionine as the variable substrate; Inhibition is competitive typeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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