BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 145 hits of affinity data for UniProtKB/TrEMBL: P67828    Zinc 0: unavailable per Zinc DB. Zinc 1: purchasable, 2 weeks to supply. Zinc 2: made on demand. Zinc 4: potentially available
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Casein Kinase I


(Homo sapiens)
CHEMBL248757
PNG
(7-chloro-3-oxo-8-[(thiazol-5-ylmethyl)-amino]-11,1...)
Show SMILES Clc1cc2NC(=O)Nc3cnc(C#N)c(OCCCCOc2cc1NCc1cncs1)n3
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
>6916.0n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Inhibition of CK1alpha1


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
H-89
PNG
(CHEMBL104264 | N-(2-{[(2E)-3-(4-bromophenyl)prop-2...)
Show SMILES Brc1ccc(\C=C\CNCCNS(=O)(=O)c2cccc3cnccc23)cc1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
ChEBI
DrugBank
IUPHAR‑DB
MMDB
PC cid
PC sid
PDB
ZINC 0

Patents


Similars

AffyNet 
PubMed
38300.0 -25.63n/an/an/an/an/an/a30



Nagoya University School of Medicine



Assay Description
Protein kinase C, cAMP dependent protein kinase, cGMP dependent protein kinase and myosin light chain kinase activity were measure under conditions d...


J Biol Chem 265: 5267-72 (1990)

More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
H-89
PNG
(CHEMBL104264 | N-(2-{[(2E)-3-(4-bromophenyl)prop-2...)
Show SMILES Brc1ccc(\C=C\CNCCNS(=O)(=O)c2cccc3cnccc23)cc1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
ChEBI
DrugBank
IUPHAR‑DB
MMDB
PC cid
PC sid
PDB
ZINC 0

Patents


Similars

AffyNet 
Article
PubMed
38300.0n/an/an/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of casein kinase 1


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
H-88
PNG
Show SMILES O=S(=O)(NCCNC\C=C\c1ccccc1)c1cccc2cnccc12
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
ZINC 0

Similars

AffyNet 
PubMed
60700.0 -24.47n/an/an/an/an/an/a30



Nagoya University School of Medicine



Assay Description
Protein kinase C, cAMP dependent protein kinase, cGMP dependent protein kinase and myosin light chain kinase activity were measure under conditions d...


J Biol Chem 265: 5267-72 (1990)

More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL219301
PNG
Show SMILES NCCNS(=O)(=O)c1cccc2c(Cl)cccc12
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0
AffyNet 
Article
PubMed
80000.0n/an/an/an/an/an/an/an/a



University of Oxford

Curated by ChEMBL


Assay Description
Inhibition of casein kinase 1


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2163772
PNG
Show SMILES Oc1ccc2oc3ncc(O)c(-c4ccccc4)c3c2c1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
>1000000.0n/an/an/an/an/an/an/an/a



Martin-Luther University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of Ck1alpha1


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL1290072
PNG
(N-(4-methoxybenzyl)benzofuro[2,3-b]pyridin-4-amine)
Show SMILES COc1ccc(CNc2ccnc3oc4ccccc4c23)cc1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
>1000000.0n/an/an/an/an/an/an/an/a



Martin Luther University Halle-Wittenberg

Curated by ChEMBL


Assay Description
Inhibition of human CK1-alpha1


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2203552
PNG
Show SMILES COc1cnc(nc1-c1cc2c(CCNC2=O)[nH]1)-c1cnc2ccccc2c1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
PDB
ZINC 0
AffyNet 
n/an/a 9.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1-alpha using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 8 uM ATP


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL215919
PNG
((R)-2-(1-Hydroxybut-2-ylamino)-6-[3-(2-pyridyl)phe...)
Show SMILES CC[C@H](CO)Nc1nc(Nc2cccc(c2)-c2ccccn2)c2ncn(C(C)C)c2n1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a 14.0n/an/an/an/an/an/a



Schering-Plough

Curated by ChEMBL


Assay Description
Inhibition of CK1


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL215919
PNG
((R)-2-(1-Hydroxybut-2-ylamino)-6-[3-(2-pyridyl)phe...)
Show SMILES CC[C@H](CO)Nc1nc(Nc2cccc(c2)-c2ccccn2)c2ncn(C(C)C)c2n1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
n/an/a 14.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counter


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2203555
PNG
Show SMILES COc1cnc(NCc2ccccc2)nc1-c1cc2c(CCNC2=O)[nH]1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
n/an/a 19.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1-alpha using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 8 uM ATP


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2203553
PNG
Show SMILES COc1cnc(\C=C\c2ccc(F)cc2)nc1-c1cc2c(CCNC2=O)[nH]1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
n/an/a 33.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1-alpha using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 8 uM ATP


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2010872
PNG
(CEP-11981)
Show SMILES CC(C)Cn1c2ccc(Nc3ncccn3)cc2c2c3CNC(=O)c3c3-c4cn(C)nc4CCc3c12
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a 48.0n/an/an/an/an/an/a



Cephalon, Inc.

Curated by ChEMBL


Assay Description
Inhibition of CK1 using ATP as substrate


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2203556
PNG
Show SMILES COc1cnc(Nc2ccccc2)nc1-c1cc2c(CCNC2=O)[nH]1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
n/an/a 54.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1-alpha using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 8 uM ATP


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2089212
PNG
Show SMILES Nc1n[nH]c2nc(Nc3cccc(NC(=O)Nc4ccc(F)c(Cl)c4)c3)ncc12
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
n/an/a 78.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counter


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2203557
PNG
Show SMILES COc1cnc(OCc2ccc(F)cc2)nc1-c1cc2c(CCNC2=O)[nH]1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
n/an/a 95.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1-alpha using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 8 uM ATP


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2089214
PNG
Show SMILES CC(C)(C)c1cc(NC(=O)Nc2cccc(Nc3ncc4c(N)n[nH]c4n3)c2)n[nH]1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0
AffyNet 
n/an/a 142.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counter


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2203559
PNG
Show SMILES COc1cnc(COc2ccc(F)cc2)nc1-c1cc2c(CCNC2=O)[nH]1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
n/an/a 146.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1-alpha using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 8 uM ATP


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2089036
PNG
Show SMILES Cl.CC(C)[C@H](N)C(=O)OC[C@H](O)CNc1nc(NCc2ccc(cc2)-c2ccccn2)c2ncn(C(C)C)c2n1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
n/an/a 150.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1 after 30 mins by liquid scintillation counter


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2203561
PNG
Show SMILES COc1cnc(COc2ccc(F)cc2)cc1-c1cc2c(CCNC2=O)[nH]1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
n/an/a 174.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1-alpha using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 8 uM ATP


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2089032
PNG
Show SMILES CC(C)n1cnc2c(NCc3ccc(cc3)-c3ccccn3)nc(NC[C@@H](O)CO)nc12
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
n/an/a 180.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1 after 30 mins by liquid scintillation counter


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2203562
PNG
Show SMILES COc1cnc(COc2ccc(F)cc2F)cc1-c1cc2c(CCNC2=O)[nH]1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
n/an/a 225.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1-alpha using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 8 uM ATP


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL466496
PNG
(3-((R)-1-Phenyl-ethylamino)-4-(pyridin-4-ylamino)-...)
Show SMILES C[C@@H](Nc1c(Nc2ccncc2)c(=O)c1=O)c1ccccc1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
ZINC 0

Patents


Similars

AffyNet 
n/an/a 250.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counter


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2203563
PNG
Show SMILES COc1cnc(COc2ccc(F)c(F)c2)cc1-c1cc2c(CCNC2=O)[nH]1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
MMDB
PC cid
PC sid
PDB
ZINC 0

Similars

AffyNet 
n/an/a 251.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1-alpha using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 8 uM ATP


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL410456
PNG
(4-(4-(2,3-Dihydrobenzo[1,4]dioxin-6-yl)-5-pyridin-...)
Show SMILES NC(=O)c1ccc(cc1)-c1nc(c([nH]1)-c1ccccn1)-c1ccc2OCCOc2c1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
IUPHAR‑DB
PC cid
PC sid
ZINC 0

Patents


Similars

AffyNet 
n/an/a 300.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counter


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL1945559
PNG
Show SMILES Cn1c2c(C(C#N)C3(CCNCC3)NC2=O)c2ccc(Cl)c(Cl)c12
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0
AffyNet 
Article
PubMed
n/an/a 330.0n/an/an/an/an/an/a



Ludwig-Maximilians University of Munich

Curated by ChEMBL


Assay Description
Inhibition of CK1alpha using ATP as substrate


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2203565
PNG
Show SMILES COc1cnc(COc2cc(F)c(F)cc2C)cc1-c1cc2c(CCNC2=O)[nH]1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
n/an/a 383.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1-alpha using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 8 uM ATP


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2089034
PNG
Show SMILES CC(C)n1cnc2c(NCc3ccc(cc3)-c3ccccn3)nc(nc12)N1C[C@H](O)C[C@H]1CO
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
n/an/a 390.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1 after 30 mins by liquid scintillation counter


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2203564
PNG
Show SMILES COc1cnc(COc2ccc(F)cc2C)cc1-c1cc2c(CCNC2=O)[nH]1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
n/an/a 442.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1-alpha using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 8 uM ATP


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens (human))
BI-D1870
PNG
(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)
Show SMILES CC(C)CCN1C(C)C(=O)N(C)c2cnc(Nc3cc(F)c(O)c(F)c3)nc12
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
ZINC 0
AffyNet 
Article
PubMed
n/an/a 450.0n/an/an/an/a7.522



University of Dundee



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] labe...


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
BI-D1870
PNG
(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)
Show SMILES CC(C)CCN1C(C)C(=O)N(C)c2cnc(Nc3cc(F)c(O)c(F)c3)nc12
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
ZINC 0
AffyNet 
n/an/a 450.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counter


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2203554
PNG
Show SMILES COc1cnc(CCc2ccc(F)cc2)nc1-c1cc2c(CCNC2=O)[nH]1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
n/an/a 568.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1-alpha using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 8 uM ATP


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2089033
PNG
Show SMILES CC(C)n1cnc2c(NCc3ccc(cc3)-c3ccccn3)nc(N[C@@H]3CCC[C@H](O)[C@@H]3O)nc12
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
n/an/a 600.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1 after 30 mins by liquid scintillation counter


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2089035
PNG
Show SMILES CC(C)n1cnc2c(NCc3ccc(cc3)-c3ccccn3)nc(NCC[C@H](O)CO)nc12
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
n/an/a 660.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1 after 30 mins by liquid scintillation counter


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2203560
PNG
Show SMILES COc1cnc(CCc2ccc(F)cc2)cc1-c1cc2c(CCNC2=O)[nH]1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
n/an/a 736.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1-alpha using biotin[long chain]-KKRRRAL{pS}VATLPGL substrate in presence of 8 uM ATP


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL489156
PNG
(3-(2,4,6-Trimethoxybenzylidene)indolin-2-one | 3-[...)
Show SMILES COc1cc(OC)c(\C=C2\C(=O)Nc3ccccc23)c(OC)c1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
ZINC 0

Patents


Similars

AffyNet 
n/an/a 1000.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counter


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL1234833
PNG
Show SMILES CC(C)c1cnn2c(NCc3ccccc3)cc(N[C@@H](CO)[C@H](O)CO)nc12
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
MMDB
PC cid
PC sid
PDB
ZINC 0

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 1040.0n/an/an/an/an/an/a



Imperial College London

Curated by ChEMBL


Assay Description
Inhibition of CK1


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL489344
PNG
(N-methyl-4-(2-(piperidin-4-yl)-5-(3-(trifluorometh...)
Show SMILES CNc1nccc(n1)-c1nc([nH]c1-c1cccc(c1)C(F)(F)F)C1CCNCC1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 1100.0n/an/an/an/an/an/a



Istituto di Ricerche di Biologia Molecolare "P. Angeletti

Curated by ChEMBL


Assay Description
Inhibition of human CKIalpha


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL489156
PNG
(3-(2,4,6-Trimethoxybenzylidene)indolin-2-one | 3-[...)
Show SMILES COc1cc(OC)c(\C=C2\C(=O)Nc3ccccc23)c(OC)c1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
DrugBank
MMDB
PC cid
PC sid
PDB
ZINC 0

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 1240.0n/an/an/an/an/an/a



Università di Padova

Curated by ChEMBL


Assay Description
Inhibition of CK1alpha (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL523938
PNG
(4-(4-(4-fluorophenyl)-2-(4-methylcyclohexyl)-1H-im...)
Show SMILES CC1CCC(CC1)c1nc(c([nH]1)-c1ccncc1)-c1ccc(F)cc1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a 1300.0n/an/an/an/an/an/a



Istituto di Ricerche di Biologia Molecolare "P. Angeletti

Curated by ChEMBL


Assay Description
Inhibition of human CKIalpha


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens (human))
CHEMBL3091536
PNG
Show SMILES Cn1c(nc(cc1=O)-c1ccncn1)N1CCO[C@H](C1)c1ccc(F)cc1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
AffyNet 
Article
PubMed
n/an/a 1500.0n/an/an/an/an/an/a



Mitsubishi Tanabe Pharma Corporation

Curated by ChEMBL


Assay Description
Inhibition of CK1 (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2089213
PNG
Show SMILES C[C@@H](NC(=O)Nc1cccc(Nc2ncc3c(N)n[nH]c3n2)c1)c1ccccc1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
n/an/a 2470.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1 using KRRRALS(p)VASLPGL as substrate after 40 mins by scintillation counter


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2071611
PNG
Show SMILES Cn1cc(cn1)-c1ccc(Nc2nc3ccc(cc3[nH]2)C#N)cc1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0
AffyNet 
Article
PubMed
n/an/a 3540.0n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of CK1alpha by Lance assay


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL86771
PNG
(1,4-diamino-9,10-anthraquinone | 1,4-diamino-anthr...)
Show SMILES Nc1ccc(N)c2C(=O)c3ccccc3C(=O)c12
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 4000.0n/an/an/an/an/an/a



Università di Padova

Curated by ChEMBL


Assay Description
Inhibition of CK1alpha (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
(R)-Roscovitine
PNG
((2R)-2-{[6-(benzylamino)-9-(propan-2-yl)-9H-purin-...)
Show SMILES CC[C@H](CO)Nc1nc(NCc2ccccc2)c2ncn(C(C)C)c2n1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
IUPHAR‑DB
MMDB
PC cid
PC sid
PDB
ZINC 0

Patents


Similars

AffyNet 
n/an/a 4000.0n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of CK1 after 30 mins by liquid scintillation counter


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL88326
PNG
(1-Amino-4-hydroxy-anthraquinone | 1-hydroxy-4-amin...)
Show SMILES Nc1ccc(O)c2C(=O)c3ccccc3C(=O)c12
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 4000.0n/an/an/an/an/an/a



Università di Padova

Curated by ChEMBL


Assay Description
Inhibition of CK1alpha (unknown origin)


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL162
PNG
((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...)
Show SMILES CN[C@@H]1CC2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
KEGG
PC cid
PC sid
PDB
ZINC 0

Patents


Similars

AffyNet 
Article
PubMed
n/an/a 4188.0n/an/an/an/an/an/a



Centre Universitaire

Curated by ChEMBL


Assay Description
Inhibition of CK1alpha1


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2071610
PNG
Show SMILES Fc1ncccc1-c1ccc(Nc2nc3ccc(cc3[nH]2)C#N)cc1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0
AffyNet 
Article
PubMed
n/an/a 4670.0n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of CK1alpha by Lance assay


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2071609
PNG
Show SMILES N#Cc1ccc2nc(Nc3ccc(cc3)-c3ccccc3)[nH]c2c1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a 5490.0n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of CK1alpha by Lance assay


Citation and Details
More data for this
Ligand-Target Pair
Casein Kinase I


(Homo sapiens)
CHEMBL2071612
PNG
Show SMILES CC(C)(C)c1ccc(Nc2nc3ccc(cc3[nH]2)C#N)cc1
NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
AffyNet 
CHEMBL
MMDB
PC cid
PC sid
PDB
ZINC 0

Similars

AffyNet 
Article
PubMed
n/an/a 7580.0n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Inhibition of CK1alpha by Lance assay


Citation and Details
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 145 total )  |  Next  |  Last  >>
Jump to: