Compile Data Set for Download or QSAR
maximum 50k data
Found 150 of ic50 for UniProtKB: P29276
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004566(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinaz...)
Affinity DataIC50:  2.80nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004566(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinaz...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50023492(5-Amino-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quinazo...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009535((CGS 22,989) 2-[6-Amino-2-(2-cyclohex-1-enyl-ethyl...)
Affinity DataIC50:  13nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataIC50:  15nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataIC50:  17nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009543(2-{6-Amino-2-[2-(5,6,7,8-tetrahydro-naphthalen-2-y...)
Affinity DataIC50:  17nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50023505(2-Furan-2-yl-9-methoxy-[1,2,4]triazolo[1,5-c]quina...)
Affinity DataIC50:  19nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50004571(8-Chloro-1-phenyl-[1,2,4]triazolo[4,3-a]quinoxalin...)
Affinity DataIC50:  21nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009509((CGS 22,492) 2-[6-Amino-2-(2-cyclohexyl-ethylamino...)
Affinity DataIC50:  22nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009546(2-{6-Amino-2-[2-(4-methoxy-phenyl)-ethylamino]-pur...)
Affinity DataIC50:  23nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015779(7,8-Dichloro-1-ethyl-[1,2,4]triazolo[4,3-a]quinoxa...)
Affinity DataIC50:  23nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009515(2-[6-Amino-2-(2-hydroxy-2-phenyl-propylamino)-puri...)
Affinity DataIC50:  24nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM21220((2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-N-ethyl-3,...)
Affinity DataIC50:  25nMAssay Description:Displacement of [3H]-NECA from adenosine A2 receptor of rat striatal membraneMore data for this Ligand-Target Pair
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009513(2-[2-(2-Adamantan-1-yl-ethylamino)-6-amino-purin-9...)
Affinity DataIC50:  27nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50023496(2-Furan-2-yl-[1,2,4]triazolo[1,5-c]quinazolin-5-yl...)
Affinity DataIC50:  27nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015765(8-Chloro-1-ethyl-[1,2,4]triazolo[4,3-a]quinoxalin-...)
Affinity DataIC50:  28nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015810(7-Chloro-1-ethyl-[1,2,4]triazolo[4,3-a]quinoxalin-...)
Affinity DataIC50:  29nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50453087(CHEMBL2374394)
Affinity DataIC50:  30nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015829(8-Chloro-1-(4-chloro-phenyl)-[1,2,4]triazolo[4,3-a...)
Affinity DataIC50:  33nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009541(2-[6-Amino-2-(2-naphthalen-2-yl-ethylamino)-purin-...)
Affinity DataIC50:  35nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015784(1-Ethyl-7-methoxy-[1,2,4]triazolo[4,3-a]quinoxalin...)
Affinity DataIC50:  36nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50453086(CHEMBL2374393)
Affinity DataIC50:  42nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009527(2-[6-Amino-2-(2-bicyclo[2.2.1]hept-2-yl-ethylamino...)
Affinity DataIC50:  42nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015798(8-Chloro-1-trifluoromethyl-[1,2,4]triazolo[4,3-a]q...)
Affinity DataIC50:  44nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009519(3-(4-{2-[6-Amino-9-(3,4-dihydroxy-5-hydroxymethyl-...)
Affinity DataIC50:  44nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009511(4-{2-[6-Amino-9-(3,4-dihydroxy-5-hydroxymethyl-tet...)
Affinity DataIC50:  49nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009545(2-{6-Amino-2-[2-(1H-indol-3-yl)-ethylamino]-purin-...)
Affinity DataIC50:  51nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50023495(2-(9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]qui...)
Affinity DataIC50:  56nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50023499((9-Chloro-2-furan-2-yl-[1,2,4]triazolo[1,5-c]quina...)
Affinity DataIC50:  61nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009516((4-{2-[6-Amino-9-(3,4-dihydroxy-5-hydroxymethyl-te...)
Affinity DataIC50:  62nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015771(1-Ethyl-[1,2,4]triazolo[4,3-a]quinoxalin-4-ylamine...)
Affinity DataIC50:  62nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009531(2-[6-Amino-2-(2-phenyl-propylamino)-purin-9-yl]-5-...)
Affinity DataIC50:  68nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009508(2-{6-Amino-2-[2-(4-bromo-thiophen-2-yl)-ethylamino...)
Affinity DataIC50:  68nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009530(3-(4-{2-[6-Amino-9-(3,4-dihydroxy-5-hydroxymethyl-...)
Affinity DataIC50:  74nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009548(2-[6-Amino-2-(4-phenyl-butylamino)-purin-9-yl]-5-h...)
Affinity DataIC50:  78nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50453083(CHEMBL2374398)
Affinity DataIC50:  87nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50453082(CHEMBL2374416)
Affinity DataIC50:  89nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50453085(CHEMBL2374396)
Affinity DataIC50:  93nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015748(8-Fluoro-1-trifluoromethyl-[1,2,4]triazolo[4,3-a]q...)
Affinity DataIC50:  100nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50015788(7-Methoxy-[1,2,4]triazolo[4,3-a]quinoxalin-4-ylami...)
Affinity DataIC50:  100nMAssay Description:Evaluated for the binding affinity towards the Adenosine A2 receptor in corpora striata of rats using [3H]NECA as radioligand.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009528(CHEMBL2374415 | [2-(4-{2-[6-Amino-9-(3,4-dihydroxy...)
Affinity DataIC50:  112nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50023503(9-Chloro-2-thiophen-2-yl-[1,2,4]triazolo[1,5-c]qui...)
Affinity DataIC50:  116nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009529(2-(6-Amino-2-{2-[4-(2-cyclohexyl-ethyl)-phenyl]-et...)
Affinity DataIC50:  120nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009540((3-{2-[6-Amino-9-(3,4-dihydroxy-5-hydroxymethyl-te...)
Affinity DataIC50:  132nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50453081(CHEMBL2374397)
Affinity DataIC50:  132nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009542(2-[6-Amino-2-(4-cyclohexyl-butylamino)-purin-9-yl]...)
Affinity DataIC50:  138nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50023506(9-Chloro-2-furan-3-yl-[1,2,4]triazolo[1,5-c]quinaz...)
Affinity DataIC50:  145nMAssay Description:Inhibition of binding to Adenosine-2 receptor using [3H]NECA in rat striatumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009520(2-[6-Amino-2-(methyl-phenethyl-amino)-purin-9-yl]-...)
Affinity DataIC50:  145nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A2a/A2b(Rattus norvegicus)
Pfizer

Curated by ChEMBL
LigandPNGBDBM82022(2-(Phenylamino)ado (CV-1808) | 2-[6-Amino-2-(3-cyc...)
Affinity DataIC50:  145nMAssay Description:Concentration required for 50% inhibition of [3H]NECA binding on rat brain adenosine A2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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