Compile Data Set for Download or QSAR
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Found 7 of ic50 for UniProtKB: P00546
TargetCyclin-dependent kinase 1(Saccharomyces cerevisiae)
University Of California

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50:  80nMAssay Description:Inhibition of Saccharomyces cerevisiae cdc28More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Saccharomyces cerevisiae)
University Of California

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of Saccharomyces cerevisiae cdc28More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Saccharomyces cerevisiae)
University Of California

Curated by ChEMBL
LigandPNGBDBM7377(4-{7-butyl-5H-pyrrolo[2,3-b]pyrazin-6-yl}phenol | ...)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of hemagglutinin-tagged Saccharomyces cerevisiae MNY629 Cdc28/Clb2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Saccharomyces cerevisiae)
University Of California

Curated by ChEMBL
LigandPNGBDBM50113707(2,6,9-Trisubstitute purine, 2 | 2-(2-hydroxyethyla...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of yeast W303 cdc28 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Saccharomyces cerevisiae)
University Of California

Curated by ChEMBL
LigandPNGBDBM50129555((1R,2R)-2-((4E,6Z)-(2S,8R,9S,11R,13S,15S,16S)-7-cy...)
Affinity DataIC50:  2.40E+4nMAssay Description:Inhibition of cyclin-dependent kinase activity of Cdc28p/CDK2p in S. cerevisiaeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Saccharomyces cerevisiae)
University Of California

Curated by ChEMBL
LigandPNGBDBM50295351(CHEMBL560452 | N-methyl-aloisine A)
Affinity DataIC50: >3.30E+4nMAssay Description:Inhibition of hemagglutinin-tagged Saccharomyces cerevisiae MNY629 Cdc28/Clb2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Saccharomyces cerevisiae)
University Of California

Curated by ChEMBL
LigandPNGBDBM50267719(2-(6-((3-chlorophenyl)(methyl)amino)-9-isopropyl-9...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of yeast W303 cdc28 phosphorylation assessed as [32P] incorporation in histone H1 from [gamma32P]ATP by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed