Compile Data Set for Download or QSAR
maximum 50k data
Found 573 of ic50 data for polymerid = 50003485
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8509((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-4-(...)
Affinity DataIC50:  37nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8513((2R)-5-[(aminiumylmethanimidoyl)amino]-2-[(4-fluor...)
Affinity DataIC50:  40nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8501((2R)-2-cyclohexyl-2-[(4-fluoro-3-methylbenzene)sul...)
Affinity DataIC50:  42nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM50236202(CHEMBL4074171)
Affinity DataIC50:  43nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8512((2R)-3-(2-aminiumylethoxy)-2-[(4-fluoro-3-methylbe...)
Affinity DataIC50:  48nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8502((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  50nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8507((2R)-3-cyclopropyl-2-[(4-fluoro-3-methylbenzene)su...)
Affinity DataIC50:  51nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8503((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  54nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8511((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-4-(...)
Affinity DataIC50:  57nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8510((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-4-[...)
Affinity DataIC50:  59nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM50236194(CHEMBL4094675)
Affinity DataIC50:  61nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8500((2R)-2-cyclopentyl-2-[(4-fluoro-3-methylbenzene)su...)
Affinity DataIC50:  64nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8508((2R,3S)-3-cyclopropyl-2-[(4-fluoro-3-methylbenzene...)
Affinity DataIC50:  65nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8506((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  67nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8505((2R,3S)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-...)
Affinity DataIC50:  67nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8496((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  70nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8514(4-[(3R)-3-[(4-fluoro-3-methylbenzene)sulfonamido]-...)
Affinity DataIC50:  75nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM50236206(CHEMBL4070379)
Affinity DataIC50:  83nMAssay Description:Inhibitor constant was measured against Muscle phosphorylase a in rabbitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM50236208(CHEMBL4081011)
Affinity DataIC50:  92nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM50070942((-)-Epigallocatechin gallate | (-)-Epigallocatechi...)
Affinity DataIC50:  97nMAssay Description:Inhibition of Bacillus anthracis lethal factorMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM50236204(CHEMBL4091315)
Affinity DataIC50:  100nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8495((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  100nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8498((2R)-2-cyclopropyl-2-[(4-fluoro-3-methylbenzene)su...)
Affinity DataIC50:  120nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8504(2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-hydrox...)
Affinity DataIC50:  120nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM50236197(CHEMBL4099044)
Affinity DataIC50:  125nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8494((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  130nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8479((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  130nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8499((2R)-2-cyclobutyl-2-[(4-fluoro-3-methylbenzene)sul...)
Affinity DataIC50:  130nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8443(2-[(5Z)-5-({5-[2-chloro-5-(trifluoromethyl)phenyl]...)
Affinity DataIC50:  190nMAssay Description:The fluorescence peptide cleavage assay was performed in a 96-well plate in which each reaction mixture contained MAPKKide, LF (List Biological Labor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM50236205(CHEMBL4064688)
Affinity DataIC50:  197nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM50236199(CHEMBL4065687)
Affinity DataIC50:  205nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM50236193(CHEMBL4104995)
Affinity DataIC50:  221nMAssay Description:Inhibitor constant was measured against Muscle phosphorylase b in rabbitMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM50236202(CHEMBL4074171)
Affinity DataIC50:  250nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM50236204(CHEMBL4091315)
Affinity DataIC50:  250nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8442(2-[(5Z)-5-{[5-(3,4-dichlorophenyl)furan-2-yl]methy...)
Affinity DataIC50:  260nMAssay Description:The fluorescence peptide cleavage assay was performed in a 96-well plate in which each reaction mixture contained MAPKKide, LF (List Biological Labor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM50236209(CHEMBL4067395)
Affinity DataIC50:  262nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8442(2-[(5Z)-5-{[5-(3,4-dichlorophenyl)furan-2-yl]methy...)
Affinity DataIC50:  265nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8476((2R)-2-[(4-fluorobenzene)sulfonamido]-N-hydroxy-3-...)
Affinity DataIC50:  290nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8441(2-[(5Z)-5-{[5-(3-chloro-4-methoxyphenyl)furan-2-yl...)
Affinity DataIC50:  298nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM50328675(CHEMBL1255963)
Affinity DataIC50:  300nMAssay Description:Inhibition of Bacillus anthracis lethal factorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8497((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  300nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8447(2-[(5Z)-5-[(5-{[(5Z)-3-(carboxymethyl)-4-oxo-2-sul...)
Affinity DataIC50:  320nMAssay Description:The fluorescence peptide cleavage assay was performed in a 96-well plate in which each reaction mixture contained MAPKKide, LF (List Biological Labor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM50236198(CHEMBL4073105)
Affinity DataIC50:  390nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8478((2R)-N-hydroxy-3-methyl-2-[(3-methylbenzene)sulfon...)
Affinity DataIC50:  400nMpH: 7.0 T: 2°CAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM50453861(CHEMBL4207547)
Affinity DataIC50:  406nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease using substrate containing CyPet and YPet linked by RRKKVYPYPMEGTIA sequence preincubated for...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8488((2R)-2-[(4-fluoronaphthalene-1-)sulfonamido]-N-hyd...)
Affinity DataIC50:  460nMAssay Description:The assay was performed in a 96-well plate, each well contained substrate peptide, LF, and the test compound. The C-terminally fluorophore of substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8494((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50:  500nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 10 mins by mobility shift protease assay using 8 uM FITC as substrateMore data for this Ligand-Target Pair
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM8439(2-[(5Z)-5-{[5-(4-chloro-2-nitrophenyl)furan-2-yl]m...)
Affinity DataIC50:  500nMAssay Description:Fluorescence peptide cleavage assay was performed in a 96-well plate. Each reaction contained MAPKKide, LF, and the small-molecule inhibitor. The C-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM50328676(CHEMBL1255964)
Affinity DataIC50:  500nMAssay Description:Inhibition of Bacillus anthracis lethal factorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLethal factor(Bacillus anthracis)
Merck Research Laboratories

LigandPNGBDBM50236203(CHEMBL4091910)
Affinity DataIC50:  558nMAssay Description:Inhibition of Bacillus anthracis lethal factor protease preincubated for 30 mins prior to addition of substrate containing fluorescent proteins CyPet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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